You may choose to remove gluten from your diet in hopes that it will clear up some of your digestive complaints or even your neurological symptoms. Other people may choose to remove all grains from their diet to improve digestion during a complete detoxification. And yet others may be under medical orders to remove gluten indefinitely, because of a diagnosis of celiac disease. Regardless of why and how long gluten is removed, you may experience a range of symptoms---positive and negative. No collection and intensity of symptoms will be exactly the same. As with any major dietary changes, consult your health care provider first.


Consumption of gluten triggers production of exorphins, which are opiate chemicals with similar results as endorphins—promoting feelings of calm. Pamela Compart and Dana Laake explain how in some people, gluten and/or casein can mimic opiates, such as morphine and heroin. When these foods are removed, intense cravings and even drug withdrawal-like symptoms can result. 2

Weight Changes

Weight gain or loss may result from removing gluten. Consuming allergenic food can result in water weight gain or edema as the body utilizes fluid as a protective barrier to the allergen. However, in others gluten induces weight loss from malabsorption of nutrients as a result of damage to the villi of the intestine.

Toxic Release and Skin Conditions

The worsening or development of a skin condition, such as rashes, hives, and acne signal that toxins are coming out through the skin as part of detoxification. As the burden on the liver diminishes and digestive capabilities improve by removing food allergens/sensitivities, the body may start to release and eliminate other toxins.

Elimination of problematic foods may eliminate or improve the skin condition.

Muscle and Joint Pain

When gluten is consumed with an allergy or sensitivity present, immune complexes are formed that get deposited in the joints, which results in painful inflammation, achy joints or arthralgia, rheumatoid arthritis, and other forms of arthritis such as:

  • episodic
  • inflammatory polyarthropathy,
  • Behcet’s syndrome


Headaches are a common symptom from food sensitivities that commonly disappear with elimination of gluten. Brostoff and Gamlin report that 70 percent of patients with migraine headaches stop getting them with removal of allergenic foods. Once the trigger foods were removed, the migraines stopped. Consuming nonsteroidal anti-inflammatory drugs for the pain of headaches will result in the same cycle of pain, inflammation, and intestinal permeability as explained in the muscle and joint pain section.

Neurological Symptoms

According to Dr. Maios Hadjivassiliou, an internationally recognized gluten researcher, gluten intolerance is manifesting as neurological symptoms instead of digestive complaints in more and more patients. Just as with physical symptoms, these may clear up with removal of the suspect food/s.

Breastfed Infants

Bed-wetting and Incontinence

Consuming problematic foods induces smooth muscle contractions, including those on the wall of the bladder. Therefore, Brostoff and Gamlin contend that eliminating problematic foods may eliminate bed-wetting and incontinence.


Removing allergenic foods frees up the immune system to fight other attackers, such as unwanted bacteria, viruses, mold and parasites. Eliminating gluten may improve the body’s ability to deal with environmental allergens and get rid of or prevent colds.


Brostoff and Gamlin note that fatigue may be one of the most common and earliest symptoms to develop from food intolerances 1. Fatigue can be a result of an overextended immune system draining the adrenals.

Hot and Cold Flashes


According to Lipski, one-third of Americans experience “heartburn” frequently, but food allergies and sensitivities are rarely considered.