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Plavix & Fish Oil
Doctors prescribe the drug Plavix to prevent blood clots and decrease the risk of heart disease and stroke. Fish oil is a common health supplement used to decrease high blood cholesterol and can also prevent blood clot formation. Therefore, taking these two medications together can lead to excessive bleeding that may be life-threatening. It is important to consult your doctor before taking fish oil and other supplements while on Plavix.
If you are experiencing serious medical symptoms, seek emergency treatment immediately.
Plavix
Plavix is a brand name for the anticoagulant medication clopidogrel bisulfate, prescribed for individuals who have had a recent stroke or heart attack or who are at risk of cardiovascular disease. Drugs.com notes that this drug prevents blood clots by inhibiting the platelets, clotting cells in your blood, from sticking or clumping together 1. Plavix improves blood flow through the arteries for better cardiovascular health.
Blood Clot Risk
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Platelets are blood cells that are the main clotting factors in your body. When an injury occurs, these cells coagulate or stick together, forming a mesh-like clot that stops bleeding. However, blood clots can also form in the blood vessels due to damage, inflammation, hardening due to atherosclerosis, injury and the buildup of fat plaques. The clots and plaques can significantly narrow and harden the arteries, hindering blood flow. The clots can also break off and travel to other parts of the body causing a thrombus or blockage. Blood clots in the heart, lungs and brain can be fatal and require urgent treatment.
- Platelets are blood cells that are the main clotting factors in your body.
- The clots can also break off and travel to other parts of the body causing a thrombus or blockage.
Fish Oil
Fish oil is a natural remedy to decrease high cholesterol or triglyceride levels and reduce the risk of atherosclerosis and heart disease. MayoClinic.com warns that fish oil contains omega 3 fatty acids, linked to decreased platelet aggregation or clumping, a prolonged bleeding time and increased fibrinolysis or the breaking down of blood clots. Though higher doses of omega 3 fatty acids appear to have these effects, you should not take fish oil with Plavix and other anticoagulant or blood-thinning medications. Ingesting high doses of fish oil can increase your risk of a hemorrhagic or bleeding stroke, nosebleeds and other abnormal bleeding.
- Fish oil is a natural remedy to decrease high cholesterol or triglyceride levels and reduce the risk of atherosclerosis and heart disease.
- Though higher doses of omega 3 fatty acids appear to have these effects, you should not take fish oil with Plavix and other anticoagulant or blood-thinning medications.
Plavix Side Effects
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Plavix can also increase your risk for life-threatening bleeding. Drugs.com advises patients taking this medication to avoid activities that increase the chance of cuts and bruising to the body 1. Seek urgent medical attention if you notice that you are bleeding excessively from a normal cut or injury or have any signs of unusual bleeding. Other side effects you should report to your doctor include:
- nosebleeds
- blood in the urine or stools
- black
- tarry stools
- an itchy skin rash
- red or purple spots on the skin
- Plavix can also increase your risk for life-threatening bleeding.
- Drugs.com advises patients taking this medication to avoid activities that increase the chance of cuts and bruising to the body 1.
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References
- Drugs.com: Plavix
- EMedTV: Side Effects of Clopidogrel
- Bittl JA, Baber U, Bradley SM, Wijeysundera DN. Duration of Dual Antiplatelet Therapy: A Systematic Review for the 2016 ACC/AHA Guideline Focused Update on Duration of Dual Antiplatelet Therapy in Patients With Coronary Artery Disease. Journal of the American College of Cardiology. 2016;68(10):1116-1139. doi:10.1016/j.jacc.2016.03.512.
- Ford MK, Cohn JR. Clopidogrel Hypersensitivity: Pathogenesis, Presentation, and Diagnosis. Curr Vasc Pharmacol. doi:10.2174/1570161116666181031143628
- Hajizadeh R, Ghaffari S, Ziaee M, Shokouhi B, Separham A, Sarbakhsh P. In vitro inhibition of platelets aggregation with generic form of clopidogrel versus branded in patients with stable angina pectoris. J Cardiovasc Thorac Res. 2017;9(4):191-195. doi:10.15171/jcvtr.2017.33
- Nadrowski P, Syzdół M, Wańha W, et al. A single-centre, randomised study on platelet reactivity after abrupt or gradual discontinuation of long-term clopidogrel therapy in patients after percutaneous coronary intervention. Kardiol Pol. 2016;74(7):634-43. doi:10.5603/KP.a2016.0006
Writer Bio
Noreen Kassem is a hospital doctor and a medical writer. Her articles have been featured in "Women's Health," "Nutrition News," "Check Up" and "Alive Magazine." Kassem also covers travel, books, fitness, nutrition, cooking and green living.