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At Healthfully, we strive to deliver objective content that is accurate and up-to-date. Our team periodically reviews articles in order to ensure content quality. The sources cited below consist of evidence from peer-reviewed journals, prominent medical organizations, academic associations, and government data.
- International Journal of Sports Physiology and Performance; Time Course of Blood Bicarbonate and pH...; M.J. Prince and M. Singh; 2008
- International Journal of Sports Physiology and Performance; Time Course of Blood Bicarbonate and pH...; M.J. Prince and M. Singh; 2008
- Journal of the American Medical Association: The Effects of Bicarbonate on Blood Coagulation; D.W. Wong, et al; 1980
- Journal of the American Medical Association: The Effects of Bicarbonate on Blood Coagulation; D.W. Wong, et al; 1980
- MayoClinic.com: Aspirin, Sodium Bicarbonate and Citric Acid (Oral Route)
The information contained on this site is for informational purposes only, and should not be used as a substitute for the advice of a professional health care provider. Please check with the appropriate physician regarding health questions and concerns. Although we strive to deliver accurate and up-to-date information, no guarantee to that effect is made.
Baking Soda and Blood Clots
Limited evidence suggests that there may be a connection between baking soda, or sodium bicarbonate, and the formation of blood clots in the body, as baking soda's influence on pH balance inhibits blood clotting. However, as scientific trials on the subject remain extremely limited, ingestion of sodium bicarbonate is not an acknowledged or recommended practice for reducing your chances of blood clots.
If you are experiencing serious medical symptoms, seek emergency treatment immediately.
Understanding Blood Clots
A blood clot, also known as deep vein thrombosis, occurs when coagulation interferes with the blood flow within a vein, potentially causing swelling, redness, pain and a life-threatening interruption in the normal functioning of the circulatory system. Typically, blood clots form because of extremely sedentary behavior, such as during bed rest following an operation. Other contributing factors may include a hereditary predisposition, extreme obesity, varicose veins or a history of strokes or paralysis.
Baking Soda and pH
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Baking soda is highly alkaline, meaning that it has a high pH value, the opposite of an acid. Ingesting baking soda therefore changes the body's internal pH value. Specifically, the pH of an individual's blood spikes within 60 to 90 minutes of consuming baking soda. The most common application of baking soda's effects on pH is evidenced in its use as an antacid. According to limited trials published in the Journal of the American Medical Association, or JAMA, baking soda's unique composition also can reduce the tendency for blood to clot properly 3. However, as reported in JAMA, the trials were based on samples of human blood and not the blood inside living organisms.
- Baking soda is highly alkaline, meaning that it has a high pH value, the opposite of an acid.
- According to limited trials published in the Journal of the American Medical Association, or JAMA, baking soda's unique composition also can reduce the tendency for blood to clot properly 3.
Baking Soda and Anticoagulants
The closest that baking soda comes to serving as a medicine to prevent blood clotting is in its use when combined with aspirin and citric acid as an anticoagulant. The three-part medication is used to reduce the likelihood of blood clotting, but it relies on aspirin to thin the blood, not baking soda. The latter ingredient simply serves as an antacid to neutralize stomach acid and reduce indigestion. MayoClinic.com advises using the medication, which is available without a prescription, only at the suggestion of your doctor. Other anticoagulants, available in both injection and pill form, may be prescribed if you have symptoms of a blood clot. Since anticoagulants thin the blood, they can be dangerous to take if you are going to undergo surgery or already are taking a salicylate-based medication.
- The closest that baking soda comes to serving as a medicine to prevent blood clotting is in its use when combined with aspirin and citric acid as an anticoagulant.
- The three-part medication is used to reduce the likelihood of blood clotting, but it relies on aspirin to thin the blood, not baking soda.
Taking Baking Soda: Additional Considerations
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Whether you're taking an aspirin- and baking soda-based medication for blood clots or a simple sodium bicarbonate-based antacid, it's inadvisable to ingest the substance if you're pregnant or nursing 4. Likewise, baking soda should not be administered orally to children ages 2 and under. Excessive intake of baking soda may result in the production of excess carbon dioxide and potential disruption of normal kidney function.
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References
- Agency for Healthcare Research and Quality: Your Guide to Preventing and Treating Blood Clots
- International Journal of Sports Physiology and Performance; Time Course of Blood Bicarbonate and pH...; M.J. Prince and M. Singh; 2008
- Journal of the American Medical Association: The Effects of Bicarbonate on Blood Coagulation; D.W. Wong, et al; 1980
- MayoClinic.com: Aspirin, Sodium Bicarbonate and Citric Acid (Oral Route)
- Medical Toxicology: Richard C. Dart
- National Center for Biotechnology Information. PubChem. Compound Summary for CID 516892, Sodium bicarbonate.
- Hadzic M, Eckstein ML, Schugardt M. The impact of sodium bicarbonate on performance in response to exercise duration in athletes: A systematic review. J Sports Sci Med. 2019;18(2):271-281
- Ciancio SG. Baking soda dentifrices and oral health. J Am Dent Assoc. 2017;148(11S):S1-S3. doi:10.1016/j.adaj.2017.09.009
- Birt D, From L, Main J. Diagnosis and management of long-standing benign oral ulceration. Laryngoscope. 1980 May;90(5 Pt 1):758-68. PMID: 6990140.
- American College of Gastroenterology. Acid reflux.
- Hughes A, Brown A, Valento M. Hemorrhagic encephalopathy from acute baking soda ingestion. West J Emerg Med. 2016;17(5):619-22. doi:10.5811/westjem2016.6.30713
- Al-Abri SA, Olson KR. Baking soda can settle the stomach but upset the heart: Case files of the Medical Toxicology Fellowship at the University of California, San Francisco. J Med Toxicol. 2013;9(3):255-8. doi:10.1007/s13181-013-0300-4
- Krustrup P, Ermidis G, Mohr M. Sodium bicarbonate intake improves high-intensity intermittent exercise performance in trained young men. J Int Soc Sports Nutr. 2015;12:25. doi:10.1186/s12970-015-0087-6
- McNaughton LR, Siegler J, Midgley A. Ergogenic effects of sodium bicarbonate. Curr Sports Med Rep. 2008;7(4):230-6. doi:10.1249/JSR.0b013e31817ef530
- de Brito-Ashurst I, Varagunam M, Raftery MJ, Yaqoob MM. Bicarbonate supplementation slows progression of CKD and improves nutritional status. J Am Soc Nephrol. 2009;20(9):2075-84. doi:10.1681/ASN.2008111205
- Yang M, Zhong X, Yuan Y. Does baking soda function as a magic bullet for patients with cancer? A mini review. Integr Cancer Ther. 2020;19:1534735420922579. doi:10.1177/153473542092257
- Yang T, Doherty J, Zhao B, Kinchla AJ, Clark JM, He L. Effectiveness of commercial and homemade washing agents in removing pesticide residues on and in apples. J Agric Food Chem. 2017;65(44):9744-9752. doi:10.1021/acs.jafc.7b03118
- Qamaruz-Zaman N, Kun Y, Rosli RN. Preliminary observation on the effect of baking soda volume on controlling odour from discarded organic waste. Waste Manag. 2015;35:187-90. doi:10.1016/j.wasman.2014.09.017
- Al-Abri SA, Kearney T. Baking soda misuse as a home remedy: case experience of the California Poison Control System. J Clin Pharm Ther. 2014;39(1):73-7. doi:10.1111/jcpt.12113
- Di Iorio BR, Bellasi A, Raphael KL, Santoro D, Aucella F, Garofano L, Ceccarelli M, Di Lullo L, Capolongo G, Di Iorio M, Guastaferro P, Capasso G; UBI Study Group. Treatment of metabolic acidosis with sodium bicarbonate delays progression of chronic kidney disease: the UBI Study. J Nephrol. 2019;32(6):989-1001. doi:10.1007/s40620-019-00656-5
Writer Bio
Danielle Hill has been writing, editing and translating since 2005. She has contributed to "Globe Pequot" Barcelona travel guide, "Gulfshore Business Magazine," "Connecting Lines: New Poetry from Mexico" and "The Barcelona Review." She has trained in neuro-linguistic programming and holds a Bachelor of Arts in comparative literature and literary translation from Brown University.