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At Healthfully, we strive to deliver objective content that is accurate and up-to-date. Our team periodically reviews articles in order to ensure content quality. The sources cited below consist of evidence from peer-reviewed journals, prominent medical organizations, academic associations, and government data.
- “Nutrition Research”; Chitosan Improves Insulin Sensitivity as Determined by the Euglycemic-hyperinsulinemic Clamp Technique in Obese Subjects; S.O. Hernández-González, et al.; June 2010
- “Nutrition Research”; Chitosan Improves Insulin Sensitivity as Determined by the Euglycemic-hyperinsulinemic Clamp Technique in Obese Subjects; S.O. Hernández-González, et al.; June 2010
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Instructions for Taking Stacker 3 Diet Pills
The "Stacker 3 with Chitosan" diet pills you find in the market today are the ephedra-free version of the original Stacker 3 diet supplement, which the manufacturer no longer produces. Stacker 3 is formulated for individuals who are at least 18 years old and not pregnant. Although this is an over-the-counter product, consult your doctor before taking this supplement.
How to Take It
If your doctor agrees Stacker 3 may help you, discuss dosage with her. The product label suggests you take one capsule after meals for a maximum of three capsules daily.
Promoter’s Claims
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The marketing material that promotes Stacker 3 as a weight-loss pill says that chitosan is a substance that binds to fat, preventing your body from accumulating it. It also asserts that Stacker 3 “increases the body’s ability to burn fat.”
About Chitosan
Chitosan comes from crustaceans or fungi. The Stacker 3 label says it contains chitosan from shellfish. The substance is made from chitin, material present in the external skeletons of crabs, lobsters, clams and other aquatic animals in the same group. According to Memorial Sloan-Kettering Cancer Center, when chitosan enters your stomach, it attaches itself to bile acids, cholesterol, fat-soluble vitamins and phospholipids 2. But science has not shown that the presence of chitosan makes your body shed more fat than when the substance is not in your stomach. Thus, it is not known why you might lose weight while taking chitosan.
- Chitosan comes from crustaceans or fungi.
- But science has not shown that the presence of chitosan makes your body shed more fat than when the substance is not in your stomach.
Chitosan and Weight Loss
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For the most part, clinical trials have failed to demonstrate that chitosan causes you to lose weight. One small study conducted in Mexico and reported in the journal “Nutrition Research” is an exception. The researchers with the Mexican Institute of Social Security found that six obese individuals who took chitosan supplements 30 minutes before meals for three months lost weight.
Chitosan Risks
If you are allergic to shellfish, the presence of crustacean chitosan in Stacker 3 may trigger a reaction. Chitosan can also cause gastrointestinal problems, including gas and constipation. Besides, this substance binds vitamins A, D, E and K, interfering with your body's absorption of these nutrients.
- If you are allergic to shellfish, the presence of crustacean chitosan in Stacker 3 may trigger a reaction.
- Besides, this substance binds vitamins A, D, E and K, interfering with your body's absorption of these nutrients.
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References
- eVitamins: Stacker 3 w/ Chitosan Ephedra Free Formula by NVE Pharmaceuticals
- Memorial Sloan-Kettering Cancer Center: Chitosan
- “Nutrition Research”; Chitosan Improves Insulin Sensitivity as Determined by the Euglycemic-hyperinsulinemic Clamp Technique in Obese Subjects; S.O. Hernández-González, et al.; June 2010
- Jull AB, Ni Mhurchu C, Bennett DA, Dunshea-Mooij CA, Rodgers A. Chitosan for overweight or obesity. Cochrane Database Syst Rev. 2008;(3):CD003892. doi:10.1002/14651858.CD003892.pub3
- Pittler MH, Ernst E. Dietary supplements for body-weight reduction: a systematic review. Am J Clin Nutr. 2004;79(4):529-536. doi:10.1093/ajcn/79.4.529
- Mhurchu CN, Dunshea-Mooij C, Bennett D, Rodgers A. Effect of chitosan on weight loss in overweight and obese individuals: a systematic review of randomized controlled trials. Obes Rev. 2005;6(1):35-42. doi:10.1111/j.1467-789X.2005.00158.x
- Moraru C, Mincea MM, Frandes M, Timar B, Ostafe V. A Meta-Analysis on Randomised Controlled Clinical Trials Evaluating the Effect of the Dietary Supplement Chitosan on Weight Loss, Lipid Parameters and Blood Pressure. Medicina (Kaunas). 2018;54(6). doi:10.3390/medicina54060109
- Memorial Sloan-Kettering Cancer Center. Chitosan. Updated November 26, 2019.
Writer Bio
Emma Watkins writes on finance, fitness and gardening. Her articles and essays have appeared in "Writer's Digest," "The Writer," "From House to Home," "Big Apple Parent" and other online and print venues. Watkins holds a Master of Arts in psychology.