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Wobenzym N Side Effects

By Emma Watkins ; Updated August 14, 2017

The promoters of Wobenzym N market it as a dietary supplement that supports muscles, tendons, joints and the immune system. The product, which has been around since 1960, is a blend of pineapple and papaya enzymes as well as pancreatic enzymes. Rutin, an antioxidant, is also included in the formula. Some side effects are associated with taking Wobenzym N. Consult your doctor before adding it to your daily regimen.

Effect on Blood Thinners

Bromelain is the pineapple enzyme in Wobenzym N. The substance interacts adversely with blood thinners, drugs such as warfarin and aspirin, that prevent blood clots from forming in the veins. The enzyme can neutralize the medicine, rendering it ineffective.

Antibiotic Interaction

Contrary to the neutralizing effect it has on blood thinners, bromelain can intensify the effects of antibiotics such as amoxicillin and tetracycline. The pineapple enzyme induces your body to absorb more of the active ingredients in the drugs, depositing more of the chemicals in the bloodstream than is safe. The fruit enzyme also increases the effects of sedatives, including certain antidepressants and drugs to combat insomnia.

Digestive Problems

Your digestive system may react adversely to the presence of bromelain. If that occurs, you may feel nauseated, vomit or come down with diarrhea, says the University of Maryland Medical Center.

Allergic Reactions

According to Drugs.com, the antioxidant rutin may cause allergic reactions that include rashes, hives, breathing problems and swelling above the neck. Stop taking Wobenzym and contact your doctor if you experience any illnesses or discomfort after you begin to use the product.

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