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At Healthfully, we strive to deliver objective content that is accurate and up-to-date. Our team periodically reviews articles in order to ensure content quality. The sources cited below consist of evidence from peer-reviewed journals, prominent medical organizations, academic associations, and government data.
- MayoClinic.com; Raynaud's Disease; November, 2009
- MayoClinic.com; Raynaud's Disease; Symptoms; November, 2009
- "Journal for Vascular Diseases"; Homocysteine levels in patients with Raynaud's phenomenon; M al-Awami et al.; May 2002
- "Journal for Vascular Diseases"; Homocysteine levels in patients with Raynaud's phenomenon; M al-Awami et al.; May 2002
- Linus Pauling Institute; Vitamin B6; ;Jane Higdon, Ph.D; Feb. 2002
The information contained on this site is for informational purposes only, and should not be used as a substitute for the advice of a professional health care provider. Please check with the appropriate physician regarding health questions and concerns. Although we strive to deliver accurate and up-to-date information, no guarantee to that effect is made.
Vitamin B-6 and Raynaud's Disease
Raynaud’s phenomenon is a condition that can cause feelings of coldness or numbness in certain parts of your body, such as your fingers, nose, ears and toes. This is due to a narrowing of the small arteries that supply blood to the skin. Taking vitamin B-6 may help to alleviate the symptoms.
Symptoms
Although Raynaud’s phenomenon is often more of an annoyance than a disability, it is more complicated than merely having cold extremities. Symptoms vary considerably depending on how often the blood vessels narrow and the severity and duration of their spasms. Symptoms include a chill feeling or numbness in the fingers or toes and color changes in the skin in response to cold temperatures or stress. During a Raynaud’s attack, the skin will first turn white and then blue as the area becomes increasingly numb. As the temperature returns the skin will redden and may throb or swell slightly.
- Although Raynaud’s phenomenon is often more of an annoyance than a disability, it is more complicated than merely having cold extremities.
- During a Raynaud’s attack, the skin will first turn white and then blue as the area becomes increasingly numb.
Causes
Niacin and Raynaud's Disease
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The cause of Raynaud’s is unknown, though it is thought that when suffers become cold or stressed, their blood vessels narrow more than those of non-sufferers, according to the University of Maryland Medical Center. There are two forms of this condition: Primary Raynaud’s is more commonly found in people who inhabit cold climates. Secondary Raynaud’s has a number of risk factors including previous frostbite, cigarette smoking, using vibrating tools, carpel tunnel syndrome and conditions such as lupus and rheumatoid arthritis.
Research
According to a study published in the May 2002 issue of the "Journal for Vascular Diseases," people who suffer from Raynaud’s disease often have higher levels of homocysteine than non-sufferers 3. Homocysteine is an amino acid produced in the body. It plays a key role in cardiovascular health and high levels can also lead to heart disease.
Vitamin B-6
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Vitamin B-6 is a water-soluble vitamin that your body cannot make, so you must obtained it from your diet. B-6 helps the brain synthesize neurotransmitters, assists red blood cell formation and helps with hormone function. Along with folic acid and vitamin B-12, vitamin B-6 also helps regulate the amino acid homocysteine. This vitamin may, therefore, be useful for the treatment of Raynaud’s disease.
- Vitamin B-6 is a water-soluble vitamin that your body cannot make, so you must obtained it from your diet.
Related Articles
References
- MayoClinic.com; Raynaud's Disease; November, 2009
- MayoClinic.com; Raynaud's Disease; Symptoms; November, 2009
- "Journal for Vascular Diseases"; Homocysteine levels in patients with Raynaud's phenomenon; M al-Awami et al.; May 2002
- Linus Pauling Institute; Vitamin B6; ;Jane Higdon, Ph.D; Feb. 2002
- Wigley F., and N. Flavahan. Raynaud's Phenomenon. The New England Journal of Medicine. 2016. 375(6):556-65. doi:10.1056/NEJMra1507638
- National Heart, Lung, and Blood Institute. Raynaud's. October 2019.
- Maverakis, E., Patel, F., Kronenberg, D. et al. International Consensus Criteria for the Diagnosis of Raynaud's Phenomenon. Journal of Autoimmunity. 2014. 48-49:60-65. doi:10.1016/j.jaut.2014.01.020
- Scleroderma Foundation. Systemic Sclerosis: Diffuse and Limited (PDF). Published January 2019.
- Herrick, A. Evidence-Based Management of Raynaud's Phenomenon. Therapeutic Advances in Musculoskeletal Diseases. 2017. 9(12):317-329. doi:10.1177/1759720X17740074
- Khouri C, Blaise S, Carpentier P, Villier C, Cracowski JL, Roustit M. Drug-induced Raynaud's phenomenon: beyond β-adrenoceptor blockers. Br J Clin Pharmacol. 2016;82(1):6–16. doi:10.1111/bcp.12912
- U.S. Department of Justice. A Guide To Disability Rights Laws. U.S. Department of Justice Civil Rights Division - Disability Rights Section. Published July 2009.
- Wigley F, Post T (ed). Treatment Of Raynaud Phenomenon: Initial Management. UpToDate. Updated December 2019
- Rinash, F., Tingey, P., Hardy, S. et al. Calcium Channel Blockers for Primary and Secondary Raynaud's Phenomenon. Cochrane Database of Systematic Reviews. 2017.12:CD000467. doi:10.1002/14651858.CD000467.pub2
- Qiu, O., Chan, T., Luen, M., Cruz, J., and E. Hermes-De Santis. Use of Nitroglycerine Ointment to Treat Primary and Secondary Raynaud's Phenomenon: A Systematic Literature Review. Rheumatology International. 2018 Aug 22. doi:10.1007/s00296-018-4119-9
- The Raynaud’s Association. Frequently Asked Questions. Updated July 2019.
- Choi, W., Choi, C., Kim, K. et al. To compare the efficacy and safety of nifedipine sustained release with Ginkgo biloba extract to treat patients with primary Raynaud’s phenomenon in South Korea; Korean Raynaud study (KOARA study). Clin Rheumatol 28, 553 (2009) doi:10.1007/s10067-008-1084-9
- Arthritis Foundation. Raynaud’s Phenomenon. Updated September 2019.
- Sufka P. Raynaud’s Phenomenon. American College of Rheumatology. Updated March 2019.
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Writer Bio
Corinna Underwood began writing in 2000. She has been published in many outlets, including Fox News, “Ultimate Athlete,” “Hardcore Muscle,” “Alternative Medicine” and “Alive.” Underwood also wrote "Haunted History of Atlanta and North Georgia" and "Murder and Mystery in Atlanta." She has a Bachelor of Arts in English literature and philosophy and a Master of Arts in women’s studies from Staffordshire University.