Topamax is a brand name for topiramate, a medication in pill or capsule form that may be prescribed for treatment of seizures. This anti-seizure epilepsy medicine may be used to control tonic-clonic seizures, partial seizures and Lennox-Gastaut syndrome. Lennox-Gastaut syndrome is a severe type of epilepsy in which there may be impairment of the intellect along with delays in development and disturbances of behavior. Topamax also may be used in the treatment of adult migraines.
If you are experiencing serious medical symptoms, seek emergency treatment immediately.
Loss of Control
The use of Topamax may cause a variety of serious side effects, and all of those associated with the bladder are considered as such. You should consult your physician immediately if you experience any serious side effects of the medication. Urinary incontinence or the loss of the ability to control the function of the bladder is a possible but rare side effect of topiramate usage 1. It means that you are unable to keep urine in until you can reach a bathroom. While the problem may cause your doctor to switch medications, if that is not possible there are some other solutions including medications and protective underwear.
- The use of Topamax may cause a variety of serious side effects, and all of those associated with the bladder are considered as such.
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Another problem in the bladder caused rarely by Topamax is the frequent need to urinate. This means you still have bladder control, but need frequent trips to the bathroom. Again, your doctor may have suggestions to counteract this, or may need to change your medication. At night, this is called nocturia. According to the National Institute of Health, younger people—up to middle age—can sleep from six to eight hours before they need to urinate. More frequently than that may signal a problem.
- Another problem in the bladder caused rarely by Topamax is the frequent need to urinate.
- This means you still have bladder control, but need frequent trips to the bathroom.
Blood in the Urine
Hematuria is the name given to the condition in which your urine contains blood, according to the Mayo Clinic. While this can be a sign of other medical conditions such as kidney disease, cancer, urinary tract infections, kidney or bladder stones, an enlarged prostate or an infection, it also may be a serious but rare side effect of Topamax. Contact your doctor if you see blood in your urine for any reason, but particularly if you are taking topiramate.
- Hematuria is the name given to the condition in which your urine contains blood, according to the Mayo Clinic.
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Dysturia is the medical term for painful urination. While it may be caused by a urinary tract infection alone, it also may be a rare side effect of Topamax usage. Your doctor may stop your use of topiramate or provide some medical alternative to experiencing dysturia.
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- National Institutes of Health website: Urinary Incontinence
- Mayo Clinic website: Topiramate
- National Institutes of Health website: Frequent or Urgent Urination
- U.S. Food and Drug Administrtion. Medication Guide: Topamax. https://www.accessdata.fda.gov/drugsatfda_docs/label/2009/020505s038s039,020844s032s034lbl.pdf
- Naegel S, Obermann M. Topiramate in the prevention and treatment of migraine: efficacy, safety and patient preference. Neuropsychiatr Dis Treat. 2010;6:17-28. doi:10.2147/ndt.s6459
- Silberstein SD. Topiramate in migraine prevention. Headache. 2005;45 Suppl 1:S57-65. doi:10.1111/j.1526-4610.2005.4501005.x
- Salek T, Andel I, Kurfurstova I. Topiramate induced metabolic acidosis and kidney stones - a case study. Biochem Med (Zagreb). 2017;27(2):404-410. doi:10.11613/BM.2017.042
- Hesami O, Hosseini SS, Kazemi N, et al. Evaluation of ocular side effects in the patients on topiramate therapy for control of migrainous headache. J Clin Diagn Res. 2016;10(3):NC01-4. doi:10.7860/JCDR/2016/16263.7339
- Meseeha MG, Attia MN, Kolade VO. Topiramate as a rare cause of reversible Fanconi syndrome and acute kidney injury: a case report and literature review. J Community Hosp Intern Med Perspect. 2016;6(1):30510. doi:10.3402/jchimp.v6.30510
- Margulis AV, Mitchell AA, Gilboa SM, et al. Use of topiramate in pregnancy and risk of oral clefts. Am J Obstet Gynecol. 2012;207(5):405.e1-7. doi:10.1016/j.ajog.2012.07.008
- Loder E, Burch R, Rizzoli P. The 2012 AHS/AAN Guidelines for Prevention of Episodic Migraine: A Summary and Comparison With Other Recent Clinical Practice Guidelines. Headache. 2012 Jun;52(6):930-45. doi: 10.1111/j.1526-4610.2012.02185.x
- Silberstein SD, Neto W, Schmitt J, Jacobs D & MIGR-001 Study Group. Topiramate in Migraine Prevention: Results of a Large Controlled Trial. Arch Neurol. 2004 Apr;61(4):490-495. doi: 10.1001/archneur.61.4.490
- Silberstein SD. Topiramate in Migraine Prevention. Headache. 2005 Apr;45 Suppl 1:S57-65. doi: 10.1111.j.1526-4610.2005.4501005.x
- U.S. Food and Drug Administrtion. Medication Guide: Topamax.
Carole Anne Tomlinson is a registered nurse with experience in rehabilitation, nutrition, chemical dependency, diabetes and health problems related to the elderly. Tomlinson holds a Bachelor of Arts in criminal justice and is presently working on her master's degree in nursing. Her screenplays have been viewed by Merchant Ivory, Angela Lansbury and Steven King's associates.