Signs & Symptoms of Lysine Deficiency
Lysine is an essential amino acid that your body needs to maintain proper growth and development. Adults should consume 12 milligrams per kilogram of body weight of lysine each day from supplements or food sources, which include red meat, potatoes, milk, fish, beans and certain soy-based products. Most people get enough lysine in their diets, according to the University of Maryland Medical Center website; however, athletes, vegans who don't eat beans, as well as burn patients may need more. If you don't get enough lysine from your diet, you might develop certain signs and symptoms associated with a lysine deficiency, which can lead to additional problems if not treated appropriately.
Appetite Loss or Poor Growth
If you have insufficient levels of lysine in your bloodstream, you may notice that your normal appetite progressively decreases. When you're not hungry, you may eat less, which may result in unintended weight loss. Additionally, poor nutrient consumption combined with low lysine levels may cause growth delays -- particularly in children or young adolescents. Consult your doctor if you develop a diminished appetite or sudden weight loss, as these lysine deficiency symptoms may also be signs of other health problems, such as diabetes or cancer.
- If you have insufficient levels of lysine in your bloodstream, you may notice that your normal appetite progressively decreases.
- Consult your doctor if you develop a diminished appetite or sudden weight loss, as these lysine deficiency symptoms may also be signs of other health problems, such as diabetes or cancer.
Fatigue or Mood Changes
Glutamine Powder or Capsules
Learn More
Low lysine levels may cause excessive fatigue, which may make it difficult for you to remain focused or attentive during your normal daily activities. You may also experience unusual mood changes, such as irritability, agitation or poor concentration. Mood-related changes may negatively affect your relationships with family, friends or colleagues. Contact your physician if you experience sudden or significant shifts in your mood to ensure that you receive appropriate treatment and care.
- Low lysine levels may cause excessive fatigue, which may make it difficult for you to remain focused or attentive during your normal daily activities.
Anemia
Anemia -- a condition in which your red blood cell levels are unusually low -- may occur if you have a lysine deficiency, warns the University of Maryland Medical Center. Symptoms associated with anemia include pale skin, dizziness, pronounced fatigue, headache and cold extremities. These symptoms may become progressively worse until your lysine levels return to normal.
Hair Loss
Lysine Overdose Symptoms
Learn More
A lysine deficiency may cause hair loss. The hair across your scalp may appear sparse or your hair may break easily while you are washing or brushing it. Excessive hair loss may be embarrassing to certain people; however, normal hair growth typically returns once your lysine levels return to normal. Consult your medical provider if you find hair loss symptoms bothersome.
- A lysine deficiency may cause hair loss.
- The hair across your scalp may appear sparse or your hair may break easily while you are washing or brushing it.
Related Articles
References
- University of Maryland Medical Center: Lysine
- Drugs.com: Lysine
- Singh M., Rao D.M., Pande S., Battu S., Mahalakshmi K., Dutt K.R., Ramesh M. Medicinal uses of l-lysine: past and future. Int. J. Res. Pharm. Sci. 2011;2:637–642
- Mailoo VJ, Rampes S. Lysine for herpes simplex prophylaxis: a review of the evidence. Integr Med (Encinitas). 2017;16(3):42-46.
- DiGiovanna JJ, Blank H. Failure of lysine in frequently recurrent herpes simplex infection. Treatment and prophylaxis. Arch Dermatol. 1984 Jan;120(1):48-51.
- Chi CC, Wang SH, Delamere FM, Wojnarowska F, Peters MC, Kanjirath PP. Interventions for prevention of herpes simplex labialis (cold sores on the lips). Cochrane Database Syst Rev. 2015; 8):CD010095. doi:10.1002/14651858.CD010095.pub2
- Singh BB, Udani J, Vinjamury SP, et al. Safety and effectiveness of an L-lysine, zinc, and herbal-based product on the treatment of facial and circumoral herpes. Altern Med Rev. 2005;10(2):123-7.
- Lakhan SE, Vieira KF. Nutritional and herbal supplements for anxiety and anxiety-related disorders: systematic review. Nutr J. 2010;9:42. doi: 0.1186/1475-2891-9-42
- Fini M, Torricelli P, Giavaresi G, Carpi A, Nicolini A, Giardino R. Effect of L-lysine and L-arginine on primary osteoblast cultures from normal and osteopenic rats. Biomed Pharmacother. 2001 May;55(4):213-20. doi:10.1016/s0753-3322(01)00054-3
- Leinonen I, Iannetta PPM, Rees RM, Russell W, Watson C, Barnes AP. Lysine supply is a critical factor in achieving sustainable global protein economy. Frontiers in Sustainable Food Systems. 2019;3. doi:10.3389/fsufs.2019.00027
- Akabas SR, Vannice G, Atwater JB, Cooperman T, Cotter R, Thomas L. Quality Certification Programs for Dietary Supplements. J Acad Nutr Diet. 2016;116(9):1370-1379. doi:10.1016/j.jand.2015.11.003
- Civitelli R, Villareal DT, Agnusdei D, Nardi P, Avioli LV, Gennari C. "Dietary L-lysine and calcium metabolism in humans." Nutrition. 1992 Nov-Dec;8(6):400-5.
- Shaheen E Lakhan, Karen F Vieira. "Nutritional and herbal supplements for anxiety and anxiety-related disorders: systematic review." Nutrition Journal. October 2010. 9:42doi:10.1186/1475-2891-9-42. 7.
- Smriga M, Ando T, Akutsu M, Furukawa Y, Miwa K, Morinaga Y. "Oral treatment with L-lysine and L-arginine reduces anxiety and basal cortisol levels in healthy humans." Biomed Res. 2007 Apr;28(2):85-90.
Writer Bio
Rae Uddin has worked as a freelance writer and editor since 2004. She specializes in scientific journalism and medical and technical writing. Her work has appeared in various online publications. Uddin earned her Master of Science in integrated biomedical sciences with an emphasis in molecular and cellular biochemistry from the University of Kentucky College of Medicine.