Lysine Overdose Symptoms
If you have oral or genital herpes, your doctor may recommend treatment with a lysine supplement. Though additional research is necessary, lysine may help reduce the replication of the herpes virus in your body, which may help reduce outbreak symptoms. Despite the health benefits of this supplement, taking too much lysine may be bad for your health. You should be aware of lysine overdose symptoms and side effects before you begin taking this supplement.
The recommended daily dose of lysine for adults is 3,000 to 9,000 mg, according to the University of Maryland Medical Center. If you take more than lysine that recommended, you may be at risk of overdosing on lysine. In humans, the symptoms of a lysine overdose are not fully known or understood. An overdose of lysine is not believed to result in fatal medical complications. However, seek emergency medical care if you believe you have taken too much lysine.
- The recommended daily dose of lysine for adults is 3,000 to 9,000 mg, according to the University of Maryland Medical Center.
- If you take more than lysine that recommended, you may be at risk of overdosing on lysine.
Gallstones or High Cholesterol
Side Effects of HCL Supplements
In animal studies, too much lysine may cause gallstones or high cholesterol, the University of Michigan Health System warns. Though high cholesterol typically does not cause noticeable symptoms, gallstones may result in abdominal pain, fever, jaundice, nausea, vomiting, bloating or clay-colored stools. If you exhibit any of these symptoms while taking lysine supplements, consult your medical provider as soon as possible.
Abdominal Cramps and Diarrhea
If you consume 15 to 40 grams of lysine each day, you may be at risk of developing abdominal cramps or diarrhea, the UMHS explains. Diarrhea results in frequent, watery bowel movements that may be accompanied by bloating, stomach pain or loss of appetite. Contact your physician if you experience chronic diarrhea, as this symptoms may increase your risk of dehydration.
What Is Lauroyl Lysine?
Inform your doctor of any health problems you may have before taking lysine supplements. Avoid treatment with lysine if you have liver or kidney disease unless otherwise instructed by a medical professional. Information regarding the safety of lysine during pregnancy is lacking and expectant or nursing mothers should avoid using this supplement.
Side Effects of HCL Supplements
What Is Lauroyl Lysine?
CLA Side Effects
Side Effects of Deglycyrrhizinated Licorice
Signs & Symptoms of Lysine Deficiency
Lysine Herpes Diet
Side Effects of the NAC Supplement
Side Effects of Zymex
Betaine Hydrochloride Side Effects
Gout and Shrimp
- Drugs.com: Lysine
- University of Pittsburg Medical Center: Lysine
- University of Maryland Medical Center: Lysine
- University of Michigan Health System: Lysine
- MedlinePlus: Gallstones
- Singh M., Rao D.M., Pande S., Battu S., Mahalakshmi K., Dutt K.R., Ramesh M. Medicinal uses of l-lysine: past and future. Int. J. Res. Pharm. Sci. 2011;2:637–642
- Mailoo VJ, Rampes S. Lysine for herpes simplex prophylaxis: a review of the evidence. Integr Med (Encinitas). 2017;16(3):42-46.
- DiGiovanna JJ, Blank H. Failure of lysine in frequently recurrent herpes simplex infection. Treatment and prophylaxis. Arch Dermatol. 1984 Jan;120(1):48-51.
- Chi CC, Wang SH, Delamere FM, Wojnarowska F, Peters MC, Kanjirath PP. Interventions for prevention of herpes simplex labialis (cold sores on the lips). Cochrane Database Syst Rev. 2015; 8):CD010095. doi:10.1002/14651858.CD010095.pub2
- Singh BB, Udani J, Vinjamury SP, et al. Safety and effectiveness of an L-lysine, zinc, and herbal-based product on the treatment of facial and circumoral herpes. Altern Med Rev. 2005;10(2):123-7.
- Lakhan SE, Vieira KF. Nutritional and herbal supplements for anxiety and anxiety-related disorders: systematic review. Nutr J. 2010;9:42. doi: 0.1186/1475-2891-9-42
- Fini M, Torricelli P, Giavaresi G, Carpi A, Nicolini A, Giardino R. Effect of L-lysine and L-arginine on primary osteoblast cultures from normal and osteopenic rats. Biomed Pharmacother. 2001 May;55(4):213-20. doi:10.1016/s0753-3322(01)00054-3
- Leinonen I, Iannetta PPM, Rees RM, Russell W, Watson C, Barnes AP. Lysine supply is a critical factor in achieving sustainable global protein economy. Frontiers in Sustainable Food Systems. 2019;3. doi:10.3389/fsufs.2019.00027
- Akabas SR, Vannice G, Atwater JB, Cooperman T, Cotter R, Thomas L. Quality Certification Programs for Dietary Supplements. J Acad Nutr Diet. 2016;116(9):1370-1379. doi:10.1016/j.jand.2015.11.003
- Civitelli R, Villareal DT, Agnusdei D, Nardi P, Avioli LV, Gennari C. "Dietary L-lysine and calcium metabolism in humans." Nutrition. 1992 Nov-Dec;8(6):400-5.
- Shaheen E Lakhan, Karen F Vieira. "Nutritional and herbal supplements for anxiety and anxiety-related disorders: systematic review." Nutrition Journal. October 2010. 9:42doi:10.1186/1475-2891-9-42. 7.
- Smriga M, Ando T, Akutsu M, Furukawa Y, Miwa K, Morinaga Y. "Oral treatment with L-lysine and L-arginine reduces anxiety and basal cortisol levels in healthy humans." Biomed Res. 2007 Apr;28(2):85-90.
Rae Uddin has worked as a freelance writer and editor since 2004. She specializes in scientific journalism and medical and technical writing. Her work has appeared in various online publications. Uddin earned her Master of Science in integrated biomedical sciences with an emphasis in molecular and cellular biochemistry from the University of Kentucky College of Medicine.