Uterine fibroids, which are also called uterine leiomyomas, are non-cancerous tumors that arise in the smooth muscle of the wall of the uterus, cervix or ovary. Fibroids are the most common type of tumor that develop in the female reproductive system. Roughly 40 percent of women over the age of 40 develop a uterine fibroid, according to an article published in the October 2000 issue of Environmental Health Perspectives 1.** Pain is the most common sign of fibroid degeneration, although different types of degeneration can cause slightly different symptoms.
Pain
Pain is the most frequent sign of uterine fibroid degeneration. The process of degeneration usually begins when the fibroid grows so large that the nearby blood vessels can no longer supply it with oxygen and nutrients. As the cells of the fibroid die, they are often replaced by collagen, the semi-rigid substance found in joints, the ears and the tip of the nose. This type of degeration is called hyaline degeneration. The pain is often severe and localized to the site of the fibroid, usually somewhere in the pelvic area, according to the University of California - San Francisco Medical Center 23. The severe pain associated with fibroid degeneration often lasts for two to four weeks, according to the University of California - San Francisco Women's Health Center 23. An over-the-counter pain reliever, such as ibuprofen or naproxen, can be taken to decrease the pain symptoms. In certain causes, the pain may not disappear after two to four weeks, resulting in chronic pelvic pain, which is also usually localized to the site of the fibroid. However, the chronic pain is generally less severe than the acute pain.
- Pain is the most frequent sign of uterine fibroid degeneration.
- In certain causes, the pain may not disappear after two to four weeks, resulting in chronic pelvic pain, which is also usually localized to the site of the fibroid.
Fever
Fibroids & Magnesium
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A fibroid can undergo a different type of degeneration known as red degeneration, or necrobiosis. This type of degeneration typically occurs during pregnancy. In addition to pelvic pain, red degeneration may cause a low-grade fever and a temporary elevation in white blood cell count, notes Cancer-Disease-Symptoms.org 4.**
- A fibroid can undergo a different type of degeneration known as red degeneration, or necrobiosis.
Bleeding
In some rare cases, a degenerating uterine fibroid may cause hemorrhage or bleeding. In these cases, the degeneration is called a carneous degeneration. The bleeding can also result in a drop in hemoglobin levels, explains Cancer-Disease-Symptoms.org 4.
- In some rare cases, a degenerating uterine fibroid may cause hemorrhage or bleeding.
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References
- University of California - San Francisco Medical Center: Fibroids
- University of California - San Francisco Women's Health Center: Fibroid Symptoms
- Uterine Fibroids. National Institutes of Health. Office on Women's Health. April 01, 2019
- What Are the Risk Factors for Uterine Fibroids? National Institutes of Health. 11/2/2018
- Wong JY, Gold EB, Johnson WO, Lee JS. Circulating Sex Hormones and Risk of Uterine Fibroids: Study of Women's Health Across the Nation (SWAN). J Clin Endocrinol Metab. 2016;101(1):123–130. doi:10.1210/jc.2015-2935
- Khan AT, Shehmar M, Gupta JK. Uterine fibroids: current perspectives. Int J Womens Health. 2014;6:95–114. Published 2014 Jan 29. doi:10.2147/IJWH.S51083
- Barra F, Seca M, Della Corte L, Giampaolino P, Ferrero S. Relugolix for the treatment of uterine fibroids. Drugs Today (Barc). 2019 Aug;55(8):503-512. doi:10.1358/dot.2019.55.8.3020179
- Barra F, Seca M, Della Corte L, Giampaolino P, Ferrero S. Relugolix for the treatment of uterine fibroids. Drugs Today (Barc). 2019 Aug;55(8):503-512. doi:10.1358/dot.2019.55.8.3020179
- Chang JH, Shin DW, Jeon MJ, Hong H, Kim SM, An A et al. Uterine Leiomyoma Is Associated with Female Sexual Dysfunction in Postmenopausal Women.Yonsei Med J. 2019 Aug;60(8):791-795. doi:10.3349/ymj.2019.60.8.791
Writer Bio
Matthew Busse has pursued professional health and science writing since 2007, writing for national publications including "Science Magazine," "New Scientist" and "The Scientist." Busse holds a doctorate in molecular biology from the University of California-San Diego.