The Side Effects of Somac

Somac is a prescription drug that contains the active ingredient pantoprozole. Somac belongs to the family of drugs called proton pump inhibitors (PPIs). These drugs work to lessen the amount of gastric acid produced by the stomach. This makes Somac an effective treatment for relieving the pain and discomfort of such stomach conditions in individuals with gastric or stomach ulcers and duodenal ulcers. Somac is available in 20 mg and 40 mg tablets.

Is This an Emergency?

If you are experiencing serious medical symptoms, seek emergency treatment immediately.


According to, about 20 million Americans develop at least one stomach ulcer during their lifetime 1. Stomach ulcers affect about 4 million Americans every year. A medication like Somac is effective at relieving the on-and-off pain of stomach ulcers by reducing the production of gastric acid in the stomach. It is also used to treat a rare condition called Zollinger-Ellison Syndrome, a condition that causes the stomach to produce an excessive amount of gastric acid.

Side Effects

Common side effects include dry mouth with a metallic taste, nausea and vomiting as well as stomach pain with indigestion or excessive gas in the stomach and bowels. In addition there may be diarrhea or constipation or headache with dizziness, weakness or tiredness. There may also be blurred vision or a skin rash with itching and increased sweating. Contact your doctor for advice if you have any of these problems.

Serious Side Effects

There may be jaundice (yellowish discoloration of the skin and/or whites of the eyes) along with dark-colored urine. Other symptoms may include:

  • unusual bleeding or bruising
  • mouth ulcers
  • chills with fever
  • swelling of the legs
  • high blood pressure
  • anxiety
  • confusion
  • depression

Seek immediate medical attention for any of these symptoms.

Allergic Reaction

An allergic reaction may be a rare but serious side effect. It is a serious medical emergency. Symptoms may include a rash or hives. There may also be swelling of the face, mouth, tongue or throat along with chest pain, shortness of breath and difficulty swallowing. Seek immediate emergency medical care for any of these symptoms.


Discuss your medical history with your doctor to include any medications you are taking. Anti-viral drugs such as atazanavir should not be taken when you are taking Somac. Discuss any allergies you may have and any history of liver or kidney diseases. Inform your doctor if you are pregnant, breast-feeding or planning to get pregnant during the time you will be taking Somac.