Side Effects of HCL Supplements
If your stomach doesn't produce enough acid to allow for proper digestion, you may have a condition called hypochlorhydria. Inadquate stomach acid production may lead to nutritional deficits, belching, heartburn, stomach discomfort and bloating. Your doctor may recommend treatment with a hydrochloric acid or HCl supplement called betaine HCl to increase the amount of acid in your stomach and alleviate hypochlorhydria symptoms. Discuss the side effects of this HCl supplement with your doctor before beginning treatment.
Heartburn
Treatment with this type of HCl supplement may cause heartburn, RxList reports. Heartburn is typically characterized by a burning sensation at the top of the abdomen that radiates upwards into the chest. If you experience frequent heartburn, you may also have a sore throat or difficulty swallowing. Consult your doctor if episodes of heartburn recur more than twice weekly, as this side effect of HCl supplements may also be a sign of alternate health conditions, such as acid reflux disease.
- Treatment with this type of HCl supplement may cause heartburn, RxList reports.
Stomach Irritation
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Taking large doses of betaine HCL may burn or degrade the lining of your stomach, HealthKey warns. Severe stomach irritation may exacerbate heartburn side effects and may also cause nausea, bloating or vomiting. Seek additional care from your doctor as soon as possible if you experience severe or chronic stomach pain.
Medical Complications
The safety and efficacy of betaine HCl supplements have not been clinically evaluated in children or pregnant or breastfeeding women. As such, this supplement should not be used by these populations unless otherwise instructed by a medical professional. Be sure to let your doctor know if you have a personal history of esophageal reflux or ulcers before you begin taking betaine HCL supplement, Baptist Health Systems advises. Treatment with this supplement may worsen symptoms associated with preexisting ulcers or reflux.
- The safety and efficacy of betaine HCl supplements have not been clinically evaluated in children or pregnant or breastfeeding women.
- Be sure to let your doctor know if you have a personal history of esophageal reflux or ulcers before you begin taking betaine HCL supplement, Baptist Health Systems advises.
Related Articles
References
- The Doctor's Medical Library: Hypochlorhydria
- U.S. Food and Drug Administration. FDA 101: Dietary supplements. July 2015.
- Yago MR, Frymoyer A, Benet LZ, et al. The use of betaine HCl to enhance dasatinib absorption in healthy volunteers with rabeprazole-induced hypochlorhydria. AAPS J. 2014;16(6):1358-1365. doi:10.1208/s12248-014-9673-9
- Kines K, Krupczak T. Nutritional interventions for gastroesophageal reflux, irritable bowel syndrome, and hypochlorhydria: A case report. Integr Med (Encinitas). 2016;15(4):49-53.
- Yago MR, Frymoyer AR, Smelick GS, et al. Gastric reacidification with betaine HCl in healthy volunteers with rabeprazole-induced hypochlorhydria. Mol Pharm. 2013;10(11):4032-4037. doi:10.1021/mp4003738
- U.S. Food and Drug Administration. Code of Federal Regulations Title 21. April 2019.
- U.S. Food and Drug Administration. FDA 101: Dietary supplements. July 2015.
Writer Bio
Rae Uddin has worked as a freelance writer and editor since 2004. She specializes in scientific journalism and medical and technical writing. Her work has appeared in various online publications. Uddin earned her Master of Science in integrated biomedical sciences with an emphasis in molecular and cellular biochemistry from the University of Kentucky College of Medicine.