Peridex Alternatives

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Peridex Mouthwash (chlorhexidine gluconate) is the first broad-spectrum antiseptic mouthwash to receive the ADA Seal of Acceptance for treatment of gingivitis. Its time-release formula reduces redness and gum swelling and helps control bleeding of gums. Children under 12 years of age should not have access to this product. If you are pregnant, nursing or sensitive to Peridex, some alternatives are available.

Stannous Fluoride

Prescription-grade stannous fluoride, dispensed by dentists, reportedly tastes better than fluoride from the pharmacy. Two of the better brands are Stanimax and PerioMed, and are sold only to dentists, not to pharmacies. Products like stannous fluoride may help children and adults who suffer from mouth ulcers induced by chemotherapy. It is a preventative as well as a therapeutic agent.

Nilstat Rinse

People undergoing intense chemotherapy are at risk for fungal and oral yeast infections evidenced by white patches in the mouth. Nilstat rinses, Mycostatin or Mycelex lozenges help treat the mouth and throat. Avoid using toothbrushes during times when gums are swollen or bleeding. Use a sponge-tip brush, a facecloth or gauze to gently clean teeth and gums prior to using any antibacterial mouth rinse product.

Magic Mouthwash

Magic Mouthwash is a prescription mixture of Benadryl, Maalox, Nystatin and lidocaine. This product numbs the mouth for about 30 minutes and helps prevent mouth sores following intense oral treatments. Used for current oral conditions, this product provides some temporary pain relief due to numbing.

Mouthwash Kits

In January 2011, CutisPharma, Inc. introduced a new line of mouthwash compounding kits for dispense by dentists and pharmacies. Ingredients are comparable to those found in Magic Mouthwash, also produced by the same company. Twelve kits on the market allows for customized prescriptions, based on individual symptoms and conditions.


Oradex has a low concentration of cholorhexidine gluconate for long-term usage. Low concentrations of the same ingredients that are in Peridex may help some people tolerate it with fewer side effects and less staining of teeth. This product does not contain alcohol, reducing the number of side effects and making it safe for children.

Hydrogen Peroxide

Hydrogen peroxide is a natural sanitizer, killing microorganisms by oxidizing them. Use 3 percent peroxide as a germicidal mouthwash or gargle. Another option is to mix baking soda with enough peroxide to make a paste for brushing your teeth with, and follow brushing with the hydrogen peroxide rinse. The taste of peroxide is unappealing and you should avoid swallowing it in large amounts or on a regular basis.