Grapefruit Seed Extract Benefits & Dosage
Grapefruit seed extract is derived from the seeds and pulp of the grapefruit. Grapefruit seed extract is purported to have antiviral, antibacterial, antifungal and anti-parasitic properties and it is used both orally and topically for a variety of health promoting purposes. As with any nutritional supplement, you should talk to your healthcare practitioner before taking grapefruit seed extract orally.
Mechanism of Action
In addition to its antimicrobial properties, Vanderbilt University states that grapefruit seed extract helps to promote detoxification and enhance immune system function. It also helps to raise the PH level of the blood and thereby alkalizes it. This is important because disease causing microorganisms such as viruses and bacteria, cannot survive in an alkaline environment and many degenerative diseases are associated with an acidic PH level. Grapefruit seed extract also has antioxidant properties and it helps to reduce free radical destruction and death to your cells and DNA.
- In addition to its antimicrobial properties, Vanderbilt University states that grapefruit seed extract helps to promote detoxification and enhance immune system function.
- Grapefruit seed extract also has antioxidant properties and it helps to reduce free radical destruction and death to your cells and DNA.
List of Purported Uses
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Grapefruit seed extract is used orally to help treat the common cold, flu, herpes, fungal infections such as candida, vaginal yeast infections, and parasitic infections such as giardia lambia. It is also used to help treat gastrointestinal disorders, irritable bowel syndrome, sinusitis, diarrhea and food poisoning. More research needs to be done to confirm the efficacy of oral grape seed extract for these purposes however.
External Benefits
Grapefruit seed has numerous external benefits. It is used topically as a facial cleanser to tone the skin, reduce oil and help treat acne and eczema. It is also used to promote hair growth, reduce muscle fatigue and treat athlete’s foot and nail fungus. In addition, it is used to disinfect, and promote the healing of, cuts and wounds. “Natural Medicines Comprehensive Database” notes that it can also be used as a vaginal douche for the treatment of vaginal infections and as an ear and nasal rinse to prevent and treat ear and nose infections. Finally, it is used as an oral rinse to sooth sore throats, prevent gingivitis, promote healthy gums and freshen the breath.
- Grapefruit seed has numerous external benefits.
- It is used topically as a facial cleanser to tone the skin, reduce oil and help treat acne and eczema.
Dosage
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Grapefruit seed extract is available in pill, powder and liquid form. The recommended dose of grapefruit seed extract for general health promoting purposes is 10 to 20 drops of liquid or 200 mg of powder or pills, three times daily. There are no serious adverse side effects reported from grapefruit seed extract, however it may interact with certain medication such as statin drugs.
Related Articles
References
- “Natural Medicines Comprehensive Database”; Therapeutic Research Faculty; 2011
- Ecomii: Grapefruit Seed Extract
- Kang ST, Son HK, Lee HJ, Choi JS, Choi YI, Lee JJ. Effects of Grapefruit Seed Extract on Oxidative Stability and Quality Properties of Cured Chicken Breast. Korean J Food Sci Anim Resour. 2017;37(3):429–439. doi:10.5851/kosfa.2017.37.3.429
- Salehi B, Fokou PVT, Sharifi-Rad M, et al. The Therapeutic Potential of Naringenin: A Review of Clinical Trials. Pharmaceuticals (Basel). 2019;12(1):11. Published 2019 Jan 10. doi:10.3390/ph12010011
- Blumenthal, M. Adulteration of “Grapefruit Seed Extract,” etc.. HerbalGram (American Botanical Council) 2012; 94:6. HerbalGram.org
- Heggers JP, Cottingham J, Gusman J, et al. The effectiveness of processed grapefruit-seed extract as an antibacterial agent: II. Mechanism of action and in vitro toxicity. J Altern Complement Med. 2002;8(3):333-40.
- Dembinski A, Warzecha Z, Konturek SJ, et al. Extract of grapefruit-seed reduces acute pancreatitis induced by ischemia/reperfusion in rats: possible implication of tissue antioxidants. J Physiol Pharmacol. 2004;55(4):811–821.
- Cardellina, J.H. The Adulteration of Commercial “Grapefruit Seed Extract” with Synthetic, Antimicrobial and Disinfectant Compounds. HerbalGram (American Botanical Council) 2012; 94:62-66. HerbalGram.org
- Dwyer JT, Coates PM, Smith MJ. Dietary Supplements: Regulatory Challenges and Research Resources. Nutrients. 2018;10(1):41. Published 2018 Jan 4. doi:10.3390/nu10010041
- de Boer A, Bast A, Godschalk R. Dietary supplement intake during pregnancy; better safe than sorry?. Regul Toxicol Pharmacol. 2018;95:442–447. doi:10.1016/j.yrtph.2018.03.014
- Taghizadeh M, Malekian E, Memarzadeh MR, Mohammadi AA, Asemi Z. Grape Seed Extract Supplementation and the Effects on the Biomarkers of Oxidative Stress and Metabolic Profiles in Female Volleyball Players: A Randomized, Double-Blind, Placebo-Controlled Clinical Trial. Iran Red Crescent Med J. 2016;18(9):e31314. Published 2016 Jul 17. doi:10.5812/ircmj.31314
- Den Hartogh DJ, Tsiani E. Antidiabetic Properties of Naringenin: A Citrus Fruit Polyphenol. Biomolecules. 2019;9(3):99. Published 2019 Mar 12. doi:10.3390/biom9030099
- Grapefruit Seed Extract. The Natural Medicines Database. Therapeutic Research Center. 2019
- Blumenthal, Mark. Adulteration of Grapefruit Seed Extract. American Botanical Council. 2012
- Dembinski A, Warzecha Z, Konturek SJ, Ceranowicz P, Dembinski M, Pawlik WW, Kusnierz-Cabala B, Naskalski JW. "Extract of grapefruit-seed reduces acute pancreatitis induced by ischemia/reperfusion in rats: possible implication of tissue antioxidants." J Physiol Pharmacol. 2004 Dec;55(4):811-21.
- Heggers JP, Cottingham J, Gusman J, Reagor L, McCoy L, Carino E, Cox R, Zhao JG. "The effectiveness of processed grapefruit-seed extract as an antibacterial agent: II. Mechanism of action and in vitro toxicity." J Altern Complement Med. 2002 Jun;8(3):333-40.
- Kang ST, Son HK, Lee HJ, Choi JS, Choi YI, Lee JJ. Effects of Grapefruit Seed Extract on Oxidative Stability and Quality Properties of Cured Chicken Breast. Korean J Food Sci Anim Resour. 2017;37(3):429–439. doi:10.5851/kosfa.2017.37.3.429
- Landberg R, Sun Q, Rimm EB, Cassidy A, Scalbert A, Mantzoros CS, Hu FB, van Dam RM. "Selected dietary flavonoids are associated with markers of inflammation and endothelial dysfunction in U.S. women." J Nutr. 2011 Apr 1;141(4):618-25.
Writer Bio
Megan Ashton began writing professionally in 2010. When she isn’t writing, she works with clients as the owner of Total Health & Hypnotherapy. She graduated from Western University with a Bachelor of Arts in communications then continued her education at the Canadian School of Natural Nutrition, where she became a Registered Holistic Nutritionist. Megan is also a Clinical Hypnotherapist.