Large Pepperoni Pizza Calories

Pepperoni is a classic pizza topping offered at nearly every place that serves pizza. When you top off a pizza with pepperoni, the amount of calories in that pizza rises.


A large, 14-inch hand-tossed pepperoni pizza from Domino's has 2,370 calories. If you substitute thin crust for hand-tossed, the calories drop to 1,870.

Papa John's

Calories in a Slice of Whole-Grain Bread

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A large, 14-inch original crust pepperoni pizza from Papa John's has 2,808 calories. A large pepperoni thin crust has 2,160 calories.

Little Caesar's

A large, original crust pepperoni pizza from Little Caesar's has 2,362 calories, while the large pepperoni deep dish has 2,486 calories.