Is Inositol Safe While Pregnant?
Inositol is a nutrient naturally found in animal products, such as beef and poultry 3. Treatment with therapeutic dosages of inositol may be beneficial for people who have depression or anxiety 3. Inositol may also help reduce symptoms associated with nerve damage caused by diabetes 3. While inositol is safe during pregnancy when consumed in the small amounts found in food, taking larger, therapeutic doses of this nutrient may not be safe 3.
If you are experiencing serious medical symptoms, seek emergency treatment immediately.
Pregnancy-Related Adverse Effects
The use of inositol during pregnancy remains controversial as of 2011 3. In a December 1998 article published in "Alternative Medicine Review," Lisa Colodny, Pharm.D 4. and Dr. Ronald L. Hoffman report that inositol may induce uterine contractions 3. Thus, taking inositol while pregnant has the potential to cause miscarriage, preterm labor or low birth weight 3. Researchers need to perform additional studies to examine the full effect of inositol in pregnant women 3. For these reasons, do not use inositol while you are pregnant without permission from your medical provider 3.
Additional Adverse Effects
Is it Safe to Take Inositol With an SSRI?
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Mild side effects that may affect anyone, including pregnant women, include:
- fatigue
- dizziness
- headache
- nausea
Although these adverse effects are usually temporary, seek care from your doctor if they persist or become severe.
Medication Interactions
In addition to pregnancy complications, medication interactions are another reason why inositol is unsafe to use during pregnancy 3. People taking lithium should discuss the use of inositol with a physician before beginning treatment 3.
Contraindications
Inositol for Anxiety
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Pregnancy isn't the only health-related reason why people shouldn't take inositol 3. If you have chronic kidney failure, do not take inositol unless otherwise instructed by a doctor 3. In addition, people with bipolar disorder shouldn't take inositol without first talking with a doctor 3. Health professionals with the University of Pittsburgh Medical Center warn that inositol may induce manic episodes in people with bipolar disorder 123.
Related Articles
References
- University of Pittsburgh Medical Center: Inositol
- University of Michigan Health System: Inositol
- RxList: Inositol
- Chiappelli, J.; Rowland, L.; Wijtenburg, A. et al. Evaluation of Myo-Inositol as a Potential Biomarker for Depression in Schizophrenia. Neuropsychopharmacology. 2015;40(9):2157-64. DOI: 10.1038/npp.2015.57.
- Giordano, D.; Corrado, F.; Santamaria, A. et al. Effects of Myo-Inositol Supplementation in Postmenopausal Women With Metabolic Syndrome: A Prospective, Randomized, Placebo-Controlled Study. Menopause. 2011;18(1):102-4. DOI: 10.1097/gme.0b013e3181e8e1b1.
- Iuorno, M.; Jakubowicz, D.; Baillargeon, J. et al. Effects of D-Chiro-Inositol in Lean Women With the Polycystic Ovary Syndrome. Endocr Pract. 2002;8(6):417-23. DOI: 10.4158/EP.8.6.417.
- Levine, J.; Barak, Y.; Szor, G. et al. Double-blind, controlled trial of inositol treatment of depression. Am J Psychiatry. 1995;152(5):792-4. DOI: 10.1176/ajp.152.5.792.
- Palatnik A, Frolov K, Fux M, Benjamin J. Double-Blind, Controlled, Crossover Trial of Inositol Versus Fluvoxamine for the Treatment of Panic Disorder. J Clin Psychopharmacol. 2001;21(3):335-9.
- Pintaudi, B.; Di Vieste, G.; and Matteo Bonomo, M. The Effectiveness of Myo-Inositol and D-Chiro Inositol Treatment in Type 2 Diabetes. Int J Endocrinol. 2016;2016:9132052. DOI: 10.1155/2016/9132052.
Writer Bio
Rae Uddin has worked as a freelance writer and editor since 2004. She specializes in scientific journalism and medical and technical writing. Her work has appeared in various online publications. Uddin earned her Master of Science in integrated biomedical sciences with an emphasis in molecular and cellular biochemistry from the University of Kentucky College of Medicine.