How to Use Melatonin to Treat Bipolar Disorder
Bipolar disorder is a medical and mental illness that impacts your mood, behavior and daily level of functioning. This illness causes mild to severe bouts of depression and mania or mixed episodes of both. During manic episodes, sleep deprivation may occur because of an increase in brain chemical activity associated with energy. This chemical imbalance alters and lowers melatonin production. Melatonin is important for stimulating sleep. Prolonged bouts of mania can eventually result in increased irritability, aggression and recklessness. Part of the treatment process for bipolar disorder is aimed at stabilizing a regular sleep schedule to reduce manic episodes.
If you are experiencing serious medical symptoms, seek emergency treatment immediately.
Discuss sleep concerns with your physician to obtain recommendations that suit your specific condition. Bipolar disorder is a serious medical condition, and use of melatonin supplements is cautioned to prevent adverse interactions. Melatonin can be stimulated naturally or with over-the-counter supplements; however, this is not advised without the supervision of your physician.
Activate natural melatonin with a light box. A light box is a small contraption used to mimic outdoor light and stimulate chemical changes in your brain. When used properly, this box can regulate your sleep cycles by generating melatonin production. Light-box therapy is used for different forms of depression and rapid-cycling bipolar disorder, notes "Psychiatric Times." Consult with your physician regarding the amount of light needed to manage your symptoms. Light boxes are sold over the counter and are generally used for 30 minutes each morning to regulate your sleep pattern.
Eat foods containing melatonin. Low doses of melatonin are in cherries, walnuts and olive oil, as well as in other varieties of fruits and vegetables. Melatonin in foods may not induce sleep; however, it does provide healthy levels of the hormone to aid in stabilizing brain chemicals associated with symptoms of irritability. Talk to your physician for nutritional recommendations of foods with melatonin.
Side Effects of a Melatonin Overdose
Change your environment. Your brain is triggered to produce melatonin upon darkness. Regulate your sleep pattern by creating a sleep environment that mimics nighttime darkness. Cover your windows with black sheets or curtains and create a sleeping area that is comfortable. Go to bed and wake up at the same times each day. Do not oversleep, because this can induce a depressive episode. Aim for seven to nine hours of nightly sleep.
Use a low-dose capsule supplement as an alternative to stimulating natural melatonin. Buy over-the-counter melatonin and follow packaging instructions for a daily dose. The University of Maryland Medical Center notes that nightly doses of melatonin at 1 mg is effective for regulating sleep, but this is subject to your individual condition 2. Work with your physician on correct dosing of capsule supplements.
Melatonin alone is not evidenced to effectively treat all of the symptoms of bipolar disorder. Consult your physician on safety of use and other options for treating your symptoms.
Melatonin as a supplement or through natural induction is primarily targeted to trigger a regular sleep pattern, which may or may not alleviate other symptoms of bipolar disorder, such as depression, hyperactivity or insomnia.
Follow physician instructions for the best course of treatment of bipolar disorder.
Follow light-box instructions accurately to prevent damage to your eyes. Do not exceed 5 mg of melatonin daily, advises MayoClinic.com. Adverse effects include dizziness, headache and disorientation.
Side Effects of a Melatonin Overdose
Neurotransmitter Foods for the Brain
Supplements to Help OCD
Side Effects of Melatonin in Children
How to Reduce Leptin Levels
The Best Dosage of Passionflower for Treating Anxiety
Gaba Vs. Kava Kava
How to Use Melatonin to Treat Acid Reflux
How to Fall into a Deep Sleep
- "Psychiatric Times"; Circadian Rhythms Factor in Rapid-Cycling Bipolar Disorder; Ellen Leibenluft, MD; May 1, 1996
- University of Maryland Medical Center; Melatonin; Steven D. Ehrlich; Dec. 8, 2009
- Cognitive Enhancement Research Institute; Melatonin; Ward Dean, MD, et al.; 2000
- MayoClinic.com; Seasonal Affective Disorder Treatment: Choosing a Light Box; Mayo Clinic staff; Oct. 1, 2010
- Buscemi N, Vandermeer B, Hooton N, et al. The efficacy and safety of exogenous melatonin for primary sleep disorders. A meta-analysis. J Gen Intern Med 2005;20:1151-8. doi:10.1111/j.1525-1497.2005.0243.x
- James M, Tremea MO, Jones JS, Krohmer JR. Can melatonin improve adaptation to night shift? Am J Emerg Med 1998;16:367-70. doi:10.1016/s0735-6757(98)90129-2
- Fischer, S., Smolnik, R., Herms, M., Born, J., and Fehm, H. L. Melatonin acutely improves the neuroendocrine architecture of sleep in blind individuals. J Clin Endocrinol.Metab 2003;88(11):5315-5320. doi10.1210/jc.2003-030540
- Gringras P, Gamble C, Jones AP, et al; MENDS Study Group. Melatonin for sleep problems in children with neurodevelopmental disorders: randomised double masked placebo controlled trial. BMJ. 2012 Nov 5;345:e6664. doi10.1136/bmj.e6664
- Jan, J. E., Hamilton, D., Seward, N., Fast, D. K., Freeman, R. D., and Laudon, M. Clinical trials of controlled-release melatonin in children with sleep- wake cycle disorders. J Pineal Res 2000;29(1):34-39.
- Nagtegaal JE, Laurant MW, Kerkhof GA, et al. Effects of melatonin on the quality of life in patients with delayed sleep phase syndrome. J Psychosom Res 2000;48:45-50. doi:10.1016/s0022-3999(99)00075-6
- Natural Standard. "Melatonin" Mayoclinic.com.
- PDRHealth. "Melatonin"
- Rossignol, D. A. and Frye, R. E. Melatonin in autism spectrum disorders: a systematic review and meta-analysis. Dev.Med.Child Neurol. 2011;53(9):783-792. doi:10.1111/j.1469-8749.2011.03980.x
- Sack RL, Brandes RW, Kendall AR, et al. Entrainment of free-running circadian rhythms by melatonin in blind people. N Engl J Med 2000;343:1070-7. doi:10.1056/NEJM200010123431503
Aubri John has been a contributing researcher and writer to online physical and mental health oriented journals since 2005. John publishes online health and fitness articles that coincide with her licensed clinical skills in addictions, psychology and medical care. She has a master's degree in clinical social work and a Ph.D. in health psychology.