Pancreatic Cancer & Fluid Buildup in the Lungs
More than 37,000 people in the United States are diagnosed with pancreatic cancer every year, mostly those over the age of 55, reports Memorial Sloan-Kettering Cancer Center 124. Typically, there are no early symptoms of pancreatic cancer, which makes it difficult to diagnose and treat successfully 24. Fluid buildup in the lungs can occur as a result of many disease processes, including metastatic cancer from the pancreas.
If you are experiencing serious medical symptoms, seek emergency treatment immediately.
Pancreatic Cancer
The most common type is adenocarcinoma, which accounts for 95 percent of all cases, reports the University of Texas MD Anderson Cancer Center 23.
Adenocarcinomas affect the cells active in secreting digestive enzymes. Most symptoms appear because of the involvement of other organs in the digestive system.
Fluid in the Lungs
Causes of Spots on Lungs
Learn More
Fluid in the lungs, also known as pulmonary edema, or PE, is not to be confused with pleural effusion, which is fluid in the tissue surrounding the lung. Symptoms of PE may include coughing, shortness of breath, diminished breath sounds and wheezing.
Causes of PE include heart conditions, pneumonia, kidney disease and cancer. Lung cancer is cancer that originates in the lung; metastatic lung cancer is cancer that originates at some other location in the body, such as the pancreas, and travels through the bloodstream to the lungs.
Identifying the cause of fluid buildup in the lungs includes diagnostic testing such as a chest X-ray or CT scan, lung needle biopsy to obtain fluid for cytologic examination and a surgical lung biopsy, if needed.
- Fluid in the lungs, also known as pulmonary edema, or PE, is not to be confused with pleural effusion, which is fluid in the tissue surrounding the lung.
- Identifying the cause of fluid buildup in the lungs includes diagnostic testing such as a chest X-ray or CT scan, lung needle biopsy to obtain fluid for cytologic examination and a surgical lung biopsy, if needed.
Treatment
Treatment options for pancreatic cancer are determined by the stage of the cancer 24. In the early stages where the cancer is contained within the pancreas, treatment options include:
- surgery to remove all or part of the pancreas
- radiation
- chemotherapy
- or a combination of radiation
- chemotherapy
Prognosis
Non-Hodgkins Lymphoma Cough Symptoms
Learn More
The outlook for people diagnosed with pancreatic cancer has historically been very poor 24. The main reason for the dismal prognosis is that symptoms indicating pancreatic cancer usually don't appear until the disease is advanced or metastasized to other organs, such as the lungs or liver 24. Since treatment options at that point are mainly directed at comfort measures, most patients die within the first year of diagnosis, according to MD Anderson Cancer Center 2.
Clinical trials are ongoing at MD Anderson Cancer Center and other locations in search of new treatment strategies that will extend the survival rate for pancreatic cancer 24.
Related Articles
References
- MD Anderson Cancer Center: Pancreatic Cancer
- Cancer.net: Pancreatic Cancer
- Nazir MA. Prevalence of periodontal disease, its association with systemic diseases and prevention. Int J Health Sci (Qassim). 2017;11(2):72–80.
- Aslanian HR, Lee JH, Canto MI. AGA Clinical Practice Update on Pancreas Cancer Screening in High-Risk Individuals: Expert Review [published online ahead of print, 2020 May 19]. Gastroenterology. 2020;S0016-5085(20)30657-0. doi:10.1053/j.gastro.2020.03.088
- American Cancer Society. Pancreatic Cancer Risk Factors. Updated February 11, 2019.
- American Society of Clinical Oncology. Pancreatic Cancer Risk Factors. May 2018.
- Eldridge RC, Gapstur SM, Newton CC, Goodman M, Patel AV, Jacobs EJ. Jewish ethnicity and pancreatic cancer mortality in a large U.S. cohort. Cancer Epidemiol Biomarkers Prev. 2011;20(4):691-8. doi:10.1158/1055-9965.EPI-10-1196
- American Cancer Society. Key Statistics for Pancreatic Cancer. Updated February 11, 2019.
- De Souza A, Irfan K, Masud F, Saif MW. Diabetes Type 2 and Pancreatic Cancer: A History Unfolding. JOP. 2016;17(2):144–148.
- Michaud DS, Joshipura K, Giovannucci E, Fuchs CS. A prospective study of periodontal disease and pancreatic cancer in US male health professionals. J Natl Cancer Inst. 2007;99(2):171-5. doi.org/10.1093/jnci/djk021
- Klein AP. Genetic susceptibility to pancreatic cancer. Mol Carcinog. 2012;51(1):14–24. doi:10.1002/mc.20855. doi:10.1002/mc.20855
- Guo Y, Liu W, Wu J. infection and pancreatic cancer risk: A meta-analysis. J Cancer Res Ther. 2016;12(Supplement):C229-C232. doi:10.4103/0973-1482.200744
- El-serag HB, Engels EA, Landgren O, et al. Risk of hepatobiliary and pancreatic cancers after hepatitis C virus infection: A population-based study of U.S. veterans. Hepatology. 2009;49(1):116-23. doi:10.1002/hep.22606
- Ilic M, Ilic I. Epidemiology of pancreatic cancer. World J Gastroenterol. 2016;22(44):9694–9705. doi:10.3748/wjg.v22.i44.9694. doi:10.3748/wjg.v22.i44.9694
- Andreotti G, Silverman DT. Occupational risk factors and pancreatic cancer: a review of recent findings. Mol Carcinog. 2012;51(1):98-108. doi:10.1002/mc.20779
- Johns Hopkins Medicine. Is Pancreatic Cancer Hereditary? Updated 2018.
- Solomon S, Das S, Brand R, Whitcomb DC. Inherited pancreatic cancer syndromes. Cancer J. 2012;18(6):485–491. doi:10.1097/PPO.0b013e318278c4a6
- Roberts NJ, Jiao Y, Yu J, et al. ATM mutations in patients with hereditary pancreatic cancer. Cancer Discov. 2012;2(1):41–46. doi:10.1158/2159-8290.CD-11-0194
- Gupta S, Wang F, Holly EA, Bracci PM. Risk of pancreatic cancer by alcohol dose, duration, and pattern of consumption, including binge drinking: a population-based study. Cancer Causes Control. 2010;21(7):1047–1059. doi:10.1007/s10552-010-9533-6
- American Cancer Society. Pancreatic Cancer Risk Factors. February 11, 2018.
- Casari I, Falasca M. Diet and Pancreatic Cancer Prevention. Cancers (Basel). 2015;7(4):2309–2317. Published 2015 Nov 23. doi:10.3390/cancers7040892
- Bao Y, Michaud DS. Physical activity and pancreatic cancer risk: a systematic review. Cancer Epidemiol Biomarkers Prev. 2008;17(10):2671–2682. doi:10.1158/1055-9965.EPI-08-0488
- Aslanian HR, Lee JH, Canto MI. AGA Clinical Practice Update on Pancreas Cancer Screening in High-Risk Individuals: Expert Review [published online ahead of print, 2020 May 19]. Gastroenterology. 2020;S0016-5085(20)30657-0. doi:10.1053/j.gastro.2020.03.088
- American Society of Clinical Oncology. Cancer.Net. Pancreatic Cancer: Risk Factors. Updated 12/16.
- Khadka, R., Tian, W., Xin, H., and R. Koirala. Risk Factor, Early Diagnosis and Overall Survival on Outcome of Association Between Pancreatic Cancer and Diabetes Mellitus: Changes and Advances, A Review. International Journal of Surgery. 2018 Mar 10. (Epub ahead of print).
- Lu, P., Shu, L., Shen, S. et al. Dietary Patterns and Pancreatic Cancer Risk: A Meta-Analysis. Nutrients. 2017. 9(1).pii:E38.
- Maisonneuve, P., Amar, S., and A. Lowenfels. Periodontal Disease, Edentulism, and Pancreatic Cancer: A Meta-Analysis. Annals of Oncology. 2017. 28(5):985-995.
- National Cancer Institute. Pancreatic Cancer Treatment (PDQ)—Patient Version. Updated 03/22/18.
Writer Bio
Norene Anderson has been a writer since 2003. She is also a registered nurse with expertise in a wide range of medical conditions and treatments. Anderson received her associate degree in nursing from Lincoln University in Jefferson City, Mo.