Exercising and having a normal weight can lower blood pressure, according to the Mayo Clinic, but many patients wishing to lower their high blood pressure, or hypertension, have turned to drugs for help 1. The alternatives are numerous. For example, diuretics, alpha and beta blockers, ACE Inhibitors, calcium channel blockers, and blood vessel dilators are used to lower the blood pressure. Some of these have been linked with serious risks for such conditions as different types of cancers, heart attack, liver damage and stroke. Side effects of these medicines are also commonly reported.
If you are experiencing serious medical symptoms, seek emergency treatment immediately.
Hypertension medicines can have many side effects, according to the John Hopkins Health Alerts. They vary significantly depending on the type of high blood pressure medication that the person is taking. The most common side effects include constipation, which is typically caused by calcium channel blockers; dry mouth, caused by central alpha agonists; dehydration caused by diuretics; dizziness caused by alpha-blockers; drowsiness, upset stomach, headaches and increased sensitivity to cold or sunlight caused by several medications.cause:
- The most common side effects include constipation
- which is typically caused by calcium channel blockers; dry mouth
- caused by central alpha agonists; dehydration caused by diuretics; dizziness caused by alpha-blockers; drowsiness
- upset stomach
- increased sensitivity to cold or sunlight caused by several medications
Side Effects of Losartan Potassium
Several types of high blood pressure medications have been linked to an elevated risk for cancer. Drs. Ilke Sipahi, Daniel I. Simon and James C. Fang completed an analysis of over 60,000 patients randomly assigned to take either placebo or a blood pressure medication known as angiotensin-receptor blocker (ARB). They found that ARB was linked to an increased risk for cancer. For example, the risk for lung cancer was 25 percent higher among participants taking ARBs than among the control subjects. These findings were published online in The "Lancet Oncology” journal in July 2010. For five years, Dr. A.L. Fitzpatrick and colleagues followed 3,198 women over age 65 taking short-acting calcium channel blockers, other types of high blood pressure medication, or no blood pressure drugs. They found that women taking calcium channel blockers were twice as likely to develop breast cancer as subjects who were not taking high blood pressure medication. The study was published in the “Cancer” journal in October 1997.
- Several types of high blood pressure medications have been linked to an elevated risk for cancer.
- For example, the risk for lung cancer was 25 percent higher among participants taking ARBs than among the control subjects.
Heart Attack and Stroke Risks
Not only are the short-acting calcium channel blockers been linked with cancer, but they have been shown to increase risk of death from a heart attack, says the National Institutes of Health, which also says they should be prescribed with caution. Statins were developed to reduce cholesterol levels, but are increasingly prescribed to lower blood pressure. ').
Side Effects of Losartan Potassium
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- Mayo Clinic: High Blood Pressure (Hypertension)
- "The Lancet Oncology" Journal; Angiotensin-Receptor Blockade and Risk of Cancer: Meta-Analysis of Randomised Controlled Trials
- MedicationSense.com: Drugs, Liver Injury, and Cancer: Is there a Connection?
- Rossitto G, Kamath G, Messerli, FH. Should alpha-blockers ever be used as antihypertensive drugs? Cleveland Clinic Journal of Medicine. 2010;77(12):884,887-888.
- Byrd JB, Venkata C, Ram S, Lerma EV. Chapter 69 - Pharmacologic treatment of hypertension. Nephrology Secrets, 4th edition. 2019:477-482. doi:10.1016/B978-0-323-47871-7.00078-2
- Kaplan SA. Side effects of alpha-blocker use: Retrograde ejaculation. Rev Urol. 2009;11(Suppl 1):S14–S18.
- ALLHAT Officers and Coordinators for the ALLHAT Collaborative Research Group. Major outcomes in high-risk hypertensive patients randomized to angiotensin-converting enzyme inhibitor or calcium channel blocker vs diuretic: The Antihypertensive and Lipid-Lowering Treatment to Prevent Heart Attack Trial (ALLHAT). JAMA. 2002;288(23):2981-97. doi:10.1001/jama.288.23.2981
- Cleveland Clinic. Are your medications causing or increasing incontinence? September 4, 2014.
- Mancia G, Fagard R, Narkiewicz K, et al. 2013 ESH/ESC guidelines for the management of arterial hypertension: The task force for the management of arterial hypertension of the European Society of Hypertension (ESH) and of the European Society of Cardiology (ESC). J Hypertens. 2013;31:1281. doi:10.1097/01.hjh.0000431740.32696.cc
- Weber MA, Schiffrin EL, White WB, et al. Clinical practice guidelines for the management of hypertension in the community a statement by the American Society of Hypertension and the International Society of Hypertension. J Hypertens. 2014;32:3. doi:10.1111/jch.12237.
Marie Cheour had her first article published in 1995, and she has since published more than 40 articles in peer-reviewed publications such as "Nature" and "Nature Neuroscience." She has worked as a college professor in Europe and in the United States. Cheour has a Ph.D. in cognitive psychology from the University of Helsinki.