Can Probiotics Be Harmful to Cancer Patients?
Your body naturally harbors a certain amount of bacteria that do not cause health problems. Instead, these bacteria have adapted to help the human body. Probiotic supplements should be used with care in cancer patients, because although they can have some benefits for health they may also be dangerous for people with a weakened immune system.
Probiotics and Acidophilus
Probiotics are microorganisms that, when ingested in sufficient amounts, can benefit the human body, the National Center for Complementary and Alternative Medicine explains. Most probiotic supplements contain bacteria, such as Lactobacillus acidophilus or Bifidobacteria, though some strains of yeast are used as probiotics. These supplements contain bacteria similar to the microorganisms in the digestive tract and replenish or boost helpful bacteria.
Benefits
Should I Take a Probiotic Every Day?
Learn More
Bacteria that live in your digestive tract are beneficial for your health. Not only do these bacteria help you digest food, but they keep infectious bacteria from colonizing your intestines, by taking up space and resources that would otherwise be used by infectious bacteria, the University of Maryland Medical Center explains. Probiotic supplements can be taken in capsule or tablet forms and are also in some foods, such as milk and yogurt.
Benefits for Cancer Patients
Sometimes probiotics are used to help cancer patients. Probiotics stimulate the immune system and some believe that probiotics eliminate carcinogens and directly kill tumor cells, the American Cancer Society explains. In theory, these bacteria also secrete B vitamins and vitamin K, which may slow tumor growth. Studies examining the effects of probiotics on cancer risk have yielded mixed results; probiotics may be able to reduce your risk of developing colon, breast and other types of cancer, but the evidence is not clear.
- Sometimes probiotics are used to help cancer patients.
- Studies examining the effects of probiotics on cancer risk have yielded mixed results; probiotics may be able to reduce your risk of developing colon, breast and other types of cancer, but the evidence is not clear.
Risks
Probiotics & Herpes
Learn More
If you have cancer and are undergoing treatment, talk to your doctor before taking probiotics. Although probiotics are generally not infectious and do not cause tissue damage, they can be dangerous if you have a severely weakened immune system, the University of Maryland Medical Center reports. Many therapies for cancer, such as radiation and chemotherapy, damage your immune system, which could allow these bacteria to spread to other tissues and cause problems, such as sepsis.
Related Articles
References
- University of Maryland Medical Center: Lactobacillus Acidophilus
- National Center for Complementary and Alternative Medicine: Probiotics
- American Cancer Society: Probiotics
- Liu L, Zhu G. Gut-Brain Axis and Mood Disorder. Front Psychiatry. 2018;9:223. doi:10.3389/fpsyt.2018.00223
- Markowiak P, Śliżewska K. Effects of Probiotics, Prebiotics, and Synbiotics on Human Health. Nutrients. 2017;9(9):1021. doi:10.3390/nu9091021
- Mcfarland LV. Meta-analysis of probiotics for the prevention of antibiotic associated diarrhea and the treatment of Clostridium difficile disease. Am J Gastroenterol. 2006;101(4):812-22. doi:10.1111/j.1572-0241.2006.00465.x
- Oak SJ, Jha R. The effects of probiotics in lactose intolerance: A systematic review. Crit Rev Food Sci Nutr. 2019;59(11):1675-1683. doi:10.1080/10408398.2018.1425977
- Upadrasta A, Madempudi RS. Probiotics and blood pressure: current insights. Integr Blood Press Control. 2016;9:33-42. doi:10.2147/IBPC.S73246
- Wang L, Guo MJ, Gao Q, et al. The effects of probiotics on total cholesterol: A meta-analysis of randomized controlled trials. Medicine (Baltimore). 2018;97(5):e9679. doi:10.1097/MD.0000000000009679
- Didari T, Mozaffari S, Nikfar S, Abdollahi M. Effectiveness of probiotics in irritable bowel syndrome: Updated systematic review with meta-analysis. World J Gastroenterol. 2015;21(10):3072-84. doi:10.3748/wjg.v21.i10.3072
- Kijmanawat A, Panburana P, Reutrakul S, Tangshewinsirikul C. Effects of probiotic supplements on insulin resistance in gestational diabetes mellitus: A double-blind randomized controlled trial. J Diabetes Investig. 2019;10(1):163-170. doi:10.1111/jdi.12863
- Hendler R, Zhang Y. Probiotics in the Treatment of Colorectal Cancer. Medicines (Basel). 2018;5(3):101. doi:10.3390/medicines5030101
- Su GL, Ko CW, Bercik P, Falck-Ytter Y, et al. AGA Clinical Practice Guidelines on the Role of Probiotics in the Management of Gastrointestinal Disorders. Gastroenterology. 2020 Aug;159(2):697-705. doi: 10.1053/j.gastro.2020.05.059.
- Govender M, Choonara YE, Kumar P, Du Toit LC, Van Vuuren S, Pillay V. A review of the advancements in probiotic delivery: Conventional vs. non-conventional formulations for intestinal flora supplementation. AAPS PharmSciTech. 2014;15(1):29-43. doi:10.1208/s12249-013-0027-1
- Stadlbauer V. Immunosuppression and probiotics: are they effective and safe? Benef Microbes. 2015;6(6):823-8. doi:10.3920/BM2015.0065
- National Center for Complementary and Integrative Health. Probiotics: In Depth.
- Iannitti T, Palmieri B. Therapeutical use of probiotic formulations in clinical practice. Clin Nutr. 2010 Jun 22. [Epub ahead of print]
Writer Bio
Adam Cloe has been published in various scientific journals, including the "Journal of Biochemistry." He is currently a pathology resident at the University of Chicago. Cloe holds a Bachelor of Arts in biochemistry from Boston University, a M.D. from the University of Chicago and a Ph.D. in pathology from the University of Chicago.