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- National Center for Complementary and Alternative Medicine: An Introduction to Probiotics
- Mayo Clinic: Lactobacillus Safety
The information contained on this site is for informational purposes only, and should not be used as a substitute for the advice of a professional health care provider. Please check with the appropriate physician regarding health questions and concerns. Although we strive to deliver accurate and up-to-date information, no guarantee to that effect is made.
Probiotics such as Kyo-Dophilus are natural supplements that contain live micro-organisms used to increase good bacteria, lactobacilli, in your intestines. Probiotics are also added to foods such as yogurt to regulate your digestive system. Scientific studies have been performed to determine if probiotics are beneficial. The studies target benefits on specific health issues, and the results related to their effectiveness have been mixed. There are side effects that primarily affect people with existing problems. Supplements are not regulated by the U.S. Food and Drug Administration and should be used under the care of your physician.
Infection
Infections are one area of concern if you use probiotics and have an already compromised immune system from chemotherapy treatments for cancer or after recently receiving a new organ. There is increased risk of infection associated with probiotic use if you have an artificial heart valve. Reports of this happening are rare although it is still recommended that if you have an artificial heart valve, you should not use probiotics unless you are directed by your health provider to do so.
Drugs
Probiotics for Pancreatitis
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You may experience an interaction if you take probiotics with certain prescription drugs. The National Center for Complementary and Alternative Medicine says that lab studies have shown taking probiotics can prolong the effects of birth control pills or other prescription medications, and may reduce the way bowel inflammation drugs work 1. Also, antibiotics that kill the bad bacteria in your body can also kill probiotics, the good bacteria, so it is suggested to use them two to three hours apart. If you have a medical condition or you are taking prescription medications, check with your doctor before using probiotics.
- You may experience an interaction if you take probiotics with certain prescription drugs.
- The National Center for Complementary and Alternative Medicine says that lab studies have shown taking probiotics can prolong the effects of birth control pills or other prescription medications, and may reduce the way bowel inflammation drugs work 1.
Digestive
Probiotics are used to improve your digestive system but can also cause problems such as gas or bloating, diarrhea and abdominal pain. One way to help is to use a smaller serving of probiotics each day. You can also take your probiotics on an empty stomach since the probiotics will be absorbed better if exposed to less stomach acid. If you have any digestion issues, discuss using probiotics with your doctor.
- Probiotics are used to improve your digestive system but can also cause problems such as gas or bloating, diarrhea and abdominal pain.
- You can also take your probiotics on an empty stomach since the probiotics will be absorbed better if exposed to less stomach acid.
Pregnancy
List of Good Bacteria
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According to the Mayo Clinic, there has not been sufficient scientific research to determine if it is safe to use probiotics when you are pregnant or nursing your baby. There was a small study in which pregnant women used probiotic tablets without incident, though further study has been recommended. Women who are pregnant or breastfeeding should only use probiotics under a doctor's care.
Pancreas
According to a probiotic patient handout from the University of Wisconsin School of Medicine and Public Health, a study of people who have severe acute pancreatitis shows that probiotic use may increase the chance of dying 2. A later review of several scientific studies did not find differences in death risks. If you have pancreatic disease, use probiotics only under the supervision of your physician.
- According to a probiotic patient handout from the University of Wisconsin School of Medicine and Public Health, a study of people who have severe acute pancreatitis shows that probiotic use may increase the chance of dying 2.
- If you have pancreatic disease, use probiotics only under the supervision of your physician.
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References
- National Center for Complementary and Alternative Medicine: An Introduction to Probiotics
- University of Wisconsin School of Medicine and Public Health: Probiotics and Prebiotics
- Liu L, Zhu G. Gut-Brain Axis and Mood Disorder. Front Psychiatry. 2018;9:223. doi:10.3389/fpsyt.2018.00223
- Markowiak P, Śliżewska K. Effects of Probiotics, Prebiotics, and Synbiotics on Human Health. Nutrients. 2017;9(9):1021. doi:10.3390/nu9091021
- Mcfarland LV. Meta-analysis of probiotics for the prevention of antibiotic associated diarrhea and the treatment of Clostridium difficile disease. Am J Gastroenterol. 2006;101(4):812-22. doi:10.1111/j.1572-0241.2006.00465.x
- Oak SJ, Jha R. The effects of probiotics in lactose intolerance: A systematic review. Crit Rev Food Sci Nutr. 2019;59(11):1675-1683. doi:10.1080/10408398.2018.1425977
- Upadrasta A, Madempudi RS. Probiotics and blood pressure: current insights. Integr Blood Press Control. 2016;9:33-42. doi:10.2147/IBPC.S73246
- Wang L, Guo MJ, Gao Q, et al. The effects of probiotics on total cholesterol: A meta-analysis of randomized controlled trials. Medicine (Baltimore). 2018;97(5):e9679. doi:10.1097/MD.0000000000009679
- Didari T, Mozaffari S, Nikfar S, Abdollahi M. Effectiveness of probiotics in irritable bowel syndrome: Updated systematic review with meta-analysis. World J Gastroenterol. 2015;21(10):3072-84. doi:10.3748/wjg.v21.i10.3072
- Kijmanawat A, Panburana P, Reutrakul S, Tangshewinsirikul C. Effects of probiotic supplements on insulin resistance in gestational diabetes mellitus: A double-blind randomized controlled trial. J Diabetes Investig. 2019;10(1):163-170. doi:10.1111/jdi.12863
- Hendler R, Zhang Y. Probiotics in the Treatment of Colorectal Cancer. Medicines (Basel). 2018;5(3):101. doi:10.3390/medicines5030101
- Su GL, Ko CW, Bercik P, Falck-Ytter Y, et al. AGA Clinical Practice Guidelines on the Role of Probiotics in the Management of Gastrointestinal Disorders. Gastroenterology. 2020 Aug;159(2):697-705. doi: 10.1053/j.gastro.2020.05.059.
- Govender M, Choonara YE, Kumar P, Du Toit LC, Van Vuuren S, Pillay V. A review of the advancements in probiotic delivery: Conventional vs. non-conventional formulations for intestinal flora supplementation. AAPS PharmSciTech. 2014;15(1):29-43. doi:10.1208/s12249-013-0027-1
- Stadlbauer V. Immunosuppression and probiotics: are they effective and safe? Benef Microbes. 2015;6(6):823-8. doi:10.3920/BM2015.0065
- National Center for Complementary and Integrative Health. Probiotics: In Depth.
- Iannitti T, Palmieri B. Therapeutical use of probiotic formulations in clinical practice. Clin Nutr. 2010 Jun 22. [Epub ahead of print]
Writer Bio
A wellness coach, Vicki Zerbee has been writing health and lifestyle articles since 1999. Specializing in fitness, nutrition, weight loss and anti-aging topics, her work has appeared on websites such as Divine Caroline and Bright Hub. Zerbee has a certificate of accounting from Bradford Business School and a professional certification in inbound marketing from HubSpot.