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At Healthfully, we strive to deliver objective content that is accurate and up-to-date. Our team periodically reviews articles in order to ensure content quality. The sources cited below consist of evidence from peer-reviewed journals, prominent medical organizations, academic associations, and government data.
- National Institutes of Health: Choline metabolism and risk of breast cancer in a population-based study
- National Institutes of Health: Choline metabolism and risk of breast cancer in a population-based study
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Will Choline Help Me Lose Weight?
Numerous diet products on the market contain various natural ingredients promising everything from weight loss to fat flushing to carbohydrate blocking. Some dietary supplements contain choline, an essential nutrient that your body produces naturally, which is vital for brain and nerve function, cell function and metabolic processes of the liver. In addition to being readily available in food sources such as peanut butter and egg yolks, choline is an ingredient in weight loss supplements; its lipotropic properties prevent fat deposition in the liver.
Nutritional Facts
According to CholineInfo.org, you may not be getting enough choline in your diet. The Food and Nutrition Board of the Institute of Medicine has set the daily recommended allowance of choline for adults at 425 mg for females and 550 mg for males.
For Weight Loss
Citicoline Vs. Choline
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Bodybuilding.com lists choline as an important dietary supplement to help you burn fat more efficiently. Choline is a nonessential micronutrient that has been shown to have a lipotropic effect, meaning it promotes the body's use of fat and may help the liver dispose of "trapped" fats. On the scale of most effective weight loss supplements, according to Nutros.com, choline is not as effective as other nutrients such as:
- pyruvate
- green tea
- 7-Keto
- but still may provide positive benefits for individuals trying to lose weight
Other Benefits
Beyond the possible benefits for weight loss, choline has been shown to have numerous health benefits. CholineInfo.org states that this vital nutrient may not only be helpful for brain and memory function, but also for its potential role in preventing age-related memory loss, dementia and Alzheimer’s disease. The National Institutes of Health funded a study in 2008 that found an association between dietary choline and a decreased risk of breast cancer 3. Supplemental choline may also help reduce overall blood cholesterol levels, according to Nutros.com.
- Beyond the possible benefits for weight loss, choline has been shown to have numerous health benefits.
- CholineInfo.org states that this vital nutrient may not only be helpful for brain and memory function, but also for its potential role in preventing age-related memory loss, dementia and Alzheimer’s disease.
Considerations
Supplements for Gallbladder Removal
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Choline marketed for fat reduction or weight loss is usually found in supplements that also containin carnitine. As a single nutrient, it is usually found under the names phosphatidylcholine or phosphatidylinositol. In addition to carnitine, choline is often combined with other B vitamins, especially inositol. While your body may not produce enough choline to support healthy functions, you can get enough dietary choline by eating foods rich in the nutrient, as opposed to taking supplements.
- Choline marketed for fat reduction or weight loss is usually found in supplements that also containin carnitine.
Warning
As with all supplements, vitamins or natural products, it is important to discuss proper dosage with your doctor. Taking too much choline can cause toxicity side effects such as vomiting, decreased blood pressure, increased sweating and salivation, and a "fishy" body odor.
Related Articles
References
- Bodybuilding.com: The Nutritional Equivalent to Liposuction
- National Institutes of Health: Choline metabolism and risk of breast cancer in a population-based study
- Gibb AJ. Choline and acetylcholine: what a difference an acetate makes! J Physiol (Lond). 2017;595(4):1021-1022. doi:10.1113/JP273666
- Zeisel SH, Da Costa KA. Choline: an essential nutrient for public health. Nutr Rev. 2009;67(11):615-23. doi:10.1111/j.1753-4887.2009.00246.x
- Nurk E, Refsum H, Bjelland I, et al. Plasma free choline, betaine and cognitive performance: the Hordaland Health Study. Br J Nutr. 2013;109(3):511-9. doi:10.1017/S0007114512001249
- Bertoia ML, Pai JK, Cooke JP, et al. Plasma homocysteine, dietary B vitamins, betaine, and choline and risk of peripheral artery disease. Atherosclerosis. 2014;235(1):94-101. doi:10.1016/j.atherosclerosis.2014.04.010
- Fischer LM, Dacosta KA, Kwock L, et al. Sex and menopausal status influence human dietary requirements for the nutrient choline. Am J Clin Nutr. 2007;85(5):1275-85. doi:10.1093/ajcn/85.5.1275
- Caudill MA. Pre- and postnatal health: evidence of increased choline needs. J Am Diet Assoc. 2010;110(8):1198-206. doi:10.1016/j.jada.2010.05.009
- Da costa KA, Gaffney CE, Fischer LM, Zeisel SH. Choline deficiency in mice and humans is associated with increased plasma homocysteine concentration after a methionine load. Am J Clin Nutr. 2005;81(2):440-4. doi:10.1093/ajcn.81.2.440
- Sherriff JL, O'Sullivan TA, Properzi C, Oddo JL, Adams LA. Choline, Its Potential Role in Nonalcoholic Fatty Liver Disease, and the Case for Human and Bacterial Genes. Adv Nutr. 2016;7(1):5-13. doi:10.3945/an.114.007955
- NIH Office of Dietary Supplements. Choline. Updated July 9, 2019.
- Zheng Y, Li Y, Rimm EB, et al. Dietary phosphatidylcholine and risk of all-cause and cardiovascular-specific mortality among US women and men. Am J Clin Nutr. 2016;104(1):173-80. doi:10.3945/ajcn.116.131771
- Institute of Medicine (US) Standing Committee on the Scientific Evaluation of Dietary Reference Intakes and its Panel on Folate, Other B Vitamins, and Choline. Dietary Reference Intakes for Thiamin, Riboflavin, Niacin, Vitamin B6, Folate, Vitamin B12, Pantothenic Acid, Biotin, and Choline. Washington (DC): National Academies Press (US); 1998.
- Bertoia ML, Pai JK, Cooke JP, et al. Plasma homocysteine, dietary B vitamins, betaine, and choline and risk of peripheral artery disease. Atherosclerosis. 2014 Jul;235(1):94-101.
- Caudill MA. Pre- and postnatal health: evidence of increased choline needs. J Am Diet Assoc. 2010 Aug;110(8):1198-206.
- Fischer LM, daCosta KA, Kwock L, et al. Sex and menopausal status influence human dietary requirements for the nutrient choline. Am J Clin Nutr. 2007 May;85(5):1275-85.
- Nurk E, Refsum H, Bjelland I, et al. Plasma free choline, betaine and cognitive performance: the Hordaland Health Study. Br J Nutr. 2013 Feb 14;109(3):511-9.
- Zheng Y, Li Y, Rimm EB, et al. Dietary phosphatidylcholine and risk of all-cause and cardiovascular-specific mortality among US women and men. Am J Clin Nutr. 2016 Jul;104(1):173-80.
Writer Bio
Alison Stellner, owner of Body Tune Personal Training, is a fitness instructor and freelance writer with more than 25 years in the health and fitness industry. Her first professional article was published in "Idea Today Fitness Magazine" in 1993. She majored in music and business administration at the University of Oklahoma.