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At Healthfully, we strive to deliver objective content that is accurate and up-to-date. Our team periodically reviews articles in order to ensure content quality. The sources cited below consist of evidence from peer-reviewed journals, prominent medical organizations, academic associations, and government data.
- Journal of Clinical Endocrinology and Metabolism: Estrogen Bioactivity in Fo-Ti and Other Herbs Used for Their Estrogen-Like Effects as Determined by a Recombinant Cell Bioassay
- Journal of Clinical Endocrinology and Metabolism: Estrogen Bioactivity in Fo-Ti and Other Herbs Used for Their Estrogen-Like Effects as Determined by a Recombinant Cell Bioassay
- Journal of Agricultural and Food Chemistry: Activation of the Ah Receptor by Extracts of Dietary Herbal Supplements, Vegetables, and Fruits
- Journal of Agricultural and Food Chemistry: Activation of the Ah Receptor by Extracts of Dietary Herbal Supplements, Vegetables, and Fruits
- Journal of Dietary Supplements: Resveratrol: Potential as Anticancer Agent.
- Journal of Dietary Supplements: Resveratrol: Potential as Anticancer Agent.
The information contained on this site is for informational purposes only, and should not be used as a substitute for the advice of a professional health care provider. Please check with the appropriate physician regarding health questions and concerns. Although we strive to deliver accurate and up-to-date information, no guarantee to that effect is made.
The Health Benefits of Fo-Ti
Fo-Ti, also known as Chinese knotweed, is a perennial vine with broad arrowhead-shaped leaves native to central and southern China. Traditional Chinese medicine uses knotweed to balance energy in the kidney meridian, strengthen bones, prevent hair loss and premature graying, and protect the skin from sun damage. Scientific inquiry has produced evidence for a variety of potential health benefits and some potential detrimental effects of Fo-Ti. Consult a qualified health practitioner before using Fo-Ti.
If you are experiencing serious medical symptoms, seek emergency treatment immediately.
Hormonal
These herbs also assist with medical management of certain types of thyroid imbalance and reduce relapses of symptoms once thyroid treatment is completed.
Anti-Cancer
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Fo-Ti may provide anti-cancer benefits, according to a study of previously published research that appeared in the March 2012 issue of the "Journal of Dietary Supplements." The plant contains high concentrations of the antioxidant resveratrol, which is thought to decrease inflammation and regulate cell growth and reproduction. Resveratrol promotes programmed cell death and prevents uncontrolled cell reproduction. It also increases the effectiveness of anti-cancer drugs. Researchers call for further studies to confirm these preliminary results in humans.
- Fo-Ti may provide anti-cancer benefits, according to a study of previously published research that appeared in the March 2012 issue of the "Journal of Dietary Supplements."
- It also increases the effectiveness of anti-cancer drugs.
Estrogenic
University of California researchers found high levels of estrogen activity in Fo-Ti, in a study published in the September 2003 issue of the "Journal of Clinical Endocrinology and Metabolism." Fo-Ti exhibited 1/300th of the activity of the hormone 17 beta-estradiol.
Cardiovascular
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A study published in the September 2011 issue of the journal "Novon" found that Fo-Ti root contains several compounds with potential cardiovascular health benefits. However, concentrations of the bioactive substances tested in the study were lower than the minimum effective level specified by the China Pharmacopoeia Committee. A variety known as Fallopia multiflora angulata contained significantly lower levels of the compounds than Fallopia multiflora 1.
Considerations
Fo-Ti may have carcinogenic properties, according to a study published in the August 2003 issue of the "Journal of Agricultural and Food Chemistry." Foods in the study that also activated the Ah receptor include:
- corn
- jalapeño peppers
- green bell peppers
- apples
- Brussels sprouts
- potatoes
Related Articles
References
- Harvard University Flora of China: Fallopia multiflora Var. angulata, A New Combination in the Polygonaceae from China
- Journal of Clinical Endocrinology and Metabolism: Estrogen Bioactivity in Fo-Ti and Other Herbs Used for Their Estrogen-Like Effects as Determined by a Recombinant Cell Bioassay
- Journal of Agricultural and Food Chemistry: Activation of the Ah Receptor by Extracts of Dietary Herbal Supplements, Vegetables, and Fruits
- Journal of Dietary Supplements: Resveratrol: Potential as Anticancer Agent.
- Anti-Aging Therapeutics, Volume 12: A4m American Academy
- Alternative Medicine Back to Nature: A J Morgan
- Ho TT, Murthy HN, Dalawai D, Bhat MA, Paek KY, Park SY. Attributes of Polygonum multiflorum to transfigure red biotechnology. Appl Microbiol Biotechnol. 2019;103(8):3317-3326. doi:10.1007/s00253-019-09709-y
- Lei X, Chen J, Ren J, et al. Liver Damage Associated with Polygonum multiflorum Thunb.: A Systematic Review of Case Reports and Case Series. Evid Based Complement Alternat Med. 2015;2015:459749. doi:10.1155/2015/459749
- National Institutes of Health. Office of Dietary Supplements. Dietary supplements: what you need to know. Reviewed January 15, 2020
- Fo-Ti. Natural Medicines Database. Professional Monograph. 2/22/2019
- Lei X, Chen J, Ren J, et al. Liver Damage Associated with Polygonum multiflorum Thunb.: A Systematic Review of Case Reports and Case Series. Evid Based Complement Alternat Med. 2015;2015:459749.
Writer Bio
Tracey Roizman, DC is a writer and speaker on natural and preventive health care and a practicing chiropractor. She also holds a B.S. in nutritional biochemistry.