What does fact checked mean?
At Healthfully, we strive to deliver objective content that is accurate and up-to-date. Our team periodically reviews articles in order to ensure content quality. The sources cited below consist of evidence from peer-reviewed journals, prominent medical organizations, academic associations, and government data.
- National Center for Complementary and Alternative Medicine: Turmeric
- Diabetes; Targeting Curcusomes to Inflammatory Dendritic Cells Inhibits NF-B and Improves Insulin Resistance in Obese Mice; S.K. Yekollu, et al.
- Diabetes; Targeting Curcusomes to Inflammatory Dendritic Cells Inhibits NF-B and Improves Insulin Resistance in Obese Mice; S.K. Yekollu, et al.
- Food and Chemical Toxicology; The Antihyperglycemic Effect of Curcumin in High Fat Diet Fed Rats. Role of TNF-α and Free Fatty Acids; M.A. El-Moselhy, et al.
- Food and Chemical Toxicology; The Antihyperglycemic Effect of Curcumin in High Fat Diet Fed Rats. Role of TNF-α and Free Fatty Acids; M.A. El-Moselhy, et al.
The information contained on this site is for informational purposes only, and should not be used as a substitute for the advice of a professional health care provider. Please check with the appropriate physician regarding health questions and concerns. Although we strive to deliver accurate and up-to-date information, no guarantee to that effect is made.
Can Turmeric Cause Blood Sugar Levels to Drop?
Turmeric is a spice widely used in Indian, Asian and African cuisines. The dried roots have also been used in traditional Ayurvedic and Chinese medicine systems for more than 4,000 years to treat inflammation, liver disease, gallstones and arthritis. There is evidence that the herb’s active ingredient, curcumin, may have antioxidant properties, although few studies have been done in humans. Because this compound may cause blood sugar to drop, consult your physician before using turmeric therapeutically if you have diabetes.
If you are experiencing serious medical symptoms, seek emergency treatment immediately.
Herb Profile
The botanical name for turmeric is Curcuma longa, also known by the common name Indian saffron. This shrub-like plant is a member of the Zingiberaceae family of plants, which also includes cardamom and ginger. Native to India, and widely cultivated throughout South Asia and Africa, turmeric is the seasoning that provides the characteristic warm flavor to Indian curry. The rootstock of this herb also lends golden color to mustard, butter and certain cheeses and flavors soups, baked goods and sweet foods in Middle Eastern cooking. Turmeric is also a food additive used as a preservative and coloring agent, often in combination with annatto.
- The botanical name for turmeric is Curcuma longa, also known by the common name Indian saffron.
- This shrub-like plant is a member of the Zingiberaceae family of plants, which also includes cardamom and ginger.
Pharmacology and Actions
How to Use Turmeric to Reduce Inflammation and Pain
Learn More
The medicinal part of the plant is the stewed and dried rhizome, which, according to the “Physicians’ Desk Reference for Herbal Medicines,” contains up to 5 percent volatile oils, including highly aromatic alpha- and beta-tumerone and zingiberene 3. The root also contains up to 5 percent curcuminoids, most notably curcumin. According to the National Center for Complementary and Alternative Medicine, this plant phenol demonstrates antioxidant, anti-inflammatory and anti-cancer activity in some animal and in vitro studies 2. The University of Maryland Medical Center says that studies with diabetic animals have also shown that turmeric lowers serum cholesterol and blood sugar levels 1.
Effects on Blood Sugar
A study published in the September 1, 2011, issue of “Diabetes” shows that curcumin blocks the activity of a protein transcription factor called nuclear factor-κB, which is involved in inflammatory responses and becomes activated when blood sugar levels are high. By injecting specific immune cells of insulin-resistant mice with curcumin compounds, the scientists were able to inhibit nuclear factor-κB and improve insulin utilization. Similar findings were reported in a study published in "Food and Chemical Toxicology" in May 2011, which also compares the efficacy of curcumin to rosiglitazone, a pharmaceutical drug used to lower blood sugar and decrease insulin sensitivity.
- A study published in the September 1, 2011, issue of “Diabetes” shows that curcumin blocks the activity of a protein transcription factor called nuclear factor-κB, which is involved in inflammatory responses and becomes activated when blood sugar levels are high.
- Similar findings were reported in a study published in "Food and Chemical Toxicology" in May 2011, which also compares the efficacy of curcumin to rosiglitazone, a pharmaceutical drug used to lower blood sugar and decrease insulin sensitivity.
Safety Precautions
Side Effects of the Curcumin in Turmeric
Learn More
Although turmeric may show promise as a potential therapy for type 2 diabetes, this herb may increase the effects of diabetes drugs and the risk of hypoglycemia, or low blood sugar. Turmeric also interacts with other medications, including stomach acid reducers and blood-thinning agents. Do not use this herb if you are pregnant or nursing, or if you have a history of liver or gallbladder disease.
Related Articles
References
- University of Maryland Medical Center: Turmeric
- National Center for Complementary and Alternative Medicine: Turmeric
- Physicians’ Desk Reference for Herbal Medicines; Thomas Brendler, et al.
- Diabetes; Targeting Curcusomes to Inflammatory Dendritic Cells Inhibits NF-B and Improves Insulin Resistance in Obese Mice; S.K. Yekollu, et al.
- Diabetes; Activation of Nuclear Factor-κB Induced by Diabetes and High Glucose Regulates a Proapoptotic Program in Retinal Pericytes; G. Romeo, et al.
- Food and Chemical Toxicology; The Antihyperglycemic Effect of Curcumin in High Fat Diet Fed Rats. Role of TNF-α and Free Fatty Acids; M.A. El-Moselhy, et al.
- National Center for Complementary and Integrative Health (NCCIH). Turmeric. Updated November 27, 2018.
- Gupta SC, Patchva S, Aggarwal BB. Therapeutic roles of curcumin: lessons learned from clinical trials. AAPS J. 2013;15(1):195-218. doi:10.1208/s12248-012-9432-8
- Daily JW, Yang M, Park S. Efficacy of turmeric extracts and curcumin for alleviating the symptoms of joint arthritis: a systematic review and meta-analysis of randomized clinical trials. J Med Food. 2016;19(8):717-29. doi:10.1089/jmf.2016.3705
- Hewlings SJ, Kalman DS. Curcumin: A review of its effects on human health. Foods. 2017;6(10). doi:10.3390/foods6100092
- Cavaleri F. Presenting a new standard drug model for turmeric and its prized extract, curcumin. Int J Inflam. 2018;2018:5023429.
- Khayat S, Fanaei H, Kheirkhah M, Moghadam ZB, Kasaeian A, Javadimehr M. Curcumin attenuates severity of premenstrual syndrome symptoms: a randomized, double-blind, placebo-controlled trial. Complement Ther Med. 2015;23(3):318-24. doi:10.1016/j.ctim.2015.04.001
- Maulina T, Diana H, Cahyanto A, Amaliya A. The efficacy of curcumin in managing acute inflammation pain on the post-surgical removal of impacted third molars patients: a randomised controlled trial. J Oral Rehabil. 2018;45(9):677-683. doi:10.1111/joor.12679
- Buhrmann C, Mobasheri A, Busch F, et al. Curcumin modulates nuclear factor kappaB (NF-kappaB)-mediated inflammation in human tenocytes in vitro: role of the phosphatidylinositol 3-kinase/Akt pathway. J Biol Chem. 2011;286(32):28556-66. doi:10.1074/jbc.M111.256180
- Fusar-poli L, Vozza L, Gabbiadini A, et al. Curcumin for depression: a meta-analysis. Crit Rev Food Sci Nutr. 2019;1-11. doi:10.1080/10408398.2019.1653260
- Kunnumakkara AB, Bordoloi D, Padmavathi G, et al. Curcumin, the golden nutraceutical: multitargeting for multiple chronic diseases. Br J Pharmacol. 2017;174(11):1325-1348. doi:10.1111/bph.13621
- Burge K, Gunasekaran A, Eckert J, Chaaban H. Curcumin and intestinal inflammatory diseases: molecular mechanisms of protection. Int J Mol Sci. 2019;20(8). doi:10.3390/ijms20081912
- Bai X, Oberley-deegan RE, Bai A, et al. Curcumin enhances human macrophage control of Mycobacterium tuberculosis infection. Respirology. 2016;21(5):951-7. doi:10.1111/resp.12762
- Lee SW, Nah SS, Byon JS, et al. Transient complete atrioventricular block associated with curcumin intake. Int J Cardiol. 2011;150(2):e50-2. doi:10.1016/j.ijcard.2009.09.530
- Milton S. Hershey Medical Center. Possible interactions with: turmeric. Updated January 5, 2015.
- American Academy of Allergy, Asthma & Immunology. Can spices cause allergic reactions?
- Tayyem RF, Heath DD, Al-delaimy WK, Rock CL. Curcumin content of turmeric and curry powders. Nutr Cancer. 2006;55(2):126-31. doi:10.1207/s15327914nc5502_2
- Gupta SC, Kismali G, Aggarwal BB. Curcumin, a component of turmeric: from farm to pharmacy. Biofactors. 2013 Jan-Feb;39(1):2-13. DOI: 10.1002/biof.1079.
- Gupta SC, Patchva S, Koh W, Aggarwal BB. Discovery of curcumin, a component of golden spice, and its miraculous biological activities. Clin Exp Pharmacol Physiol. 2012 Mar;39(3):283-99. DOI: 10.1111/j.1440-1681.2011.05648.x.
- Patrick K, Stanbrook MB. Take turmeric with a grain of salt. CMAJ. 2018;190(43):E1270. doi:10.1503/cmaj.181358
Writer Bio
Karyn Maier is a seasoned columnist and feature writer. Since 1992, her work has appeared in Mother Earth News, The Herb Quarterly, Better Nutrition and in many other print and digital publications. She is also the author of five books, and is published in six languages.