What Is the Difference Between HGH and DHEA?
Human growth hormone, or HGH, and dhydroepiandrosterone, or DHEA,are both hormones made by your body 1. They serve distinct functions though and have been the subject of controversy due to their use by athletes and individuals wanting to slow the aging process. Your body does not readily accept hormones introduced through supplementation, and taking hormone supplements, including HGH and DHEA, can cause serious health problems. You should, therefore, consult your doctor before taking an HGH or DHEA supplement.
HGH
Your pituitary gland, a small structure at the base of your brain, produces the HGH hormone. Your body uses HGH to build muscles and organ tissues. Your body produces a higher quantity of HGH during childhood and adolescence to promote growth. As you age, the amount of HGH produced by your body starts to decline. This decline may promote the visible signs of aging in your body. Therefore, manufacturers of HGH claim that injecting this hormone into your body can slow or even reverse many of the signs of aging. Available clinical evidence does not, however, support these anti-aging claims, as of the time of publication.
- Your pituitary gland, a small structure at the base of your brain, produces the HGH hormone.
- As you age, the amount of HGH produced by your body starts to decline.
Uses for HGH
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Doctors commonly prescribe HGH for children who have abnormal growth rates. Doctors administer HGH to these children to stimulate children’ natural HGH production. It is rare for adults to have a growth hormone deficiency, but doctors may prescribe HGH supplements to adults who have AIDS and certain types of cancers to prevent wasting syndrome, a disorder characterized by the wasting away of muscle tissue. HGH injections can increase your bone density, muscle mass, physical capacity and decrease your overall body fat.
- Doctors commonly prescribe HGH for children who have abnormal growth rates.
- It is rare for adults to have a growth hormone deficiency, but doctors may prescribe HGH supplements to adults who have AIDS and certain types of cancers to prevent wasting syndrome, a disorder characterized by the wasting away of muscle tissue.
DHEA
Your adrenal glands that sit atop your kidneys produce DHEA. DHEA is an endogenous hormone made in your body used to produce both male and female sex hormones. DHEA production in your body peaks at around the age of 20 and declines as you age. Different physical ailments also can cause your body to produce less DHEA. Ailments that can reduce your DHEA levels include diabetes, AIDS, end stage kidney disease, coronary artery disease and rheumatoid arthritis.
- Your adrenal glands that sit atop your kidneys produce DHEA.
Uses of DHEA
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DHEA has had several different applications. You can use DHEA to treat Addison’s disease, lupus, osteoporosis and erectile dysfunction. Although DHEA has many several purported medical applications, clinical evidence does not support the use of DHEA to treat specific medical conditions. You should consult a doctor before consuming any DHEA supplement.
- DHEA has had several different applications.
- Although DHEA has many several purported medical applications, clinical evidence does not support the use of DHEA to treat specific medical conditions.
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References
- "HGH (Human Growth Hormone): Age-Reversing Miracle (Woodland Health Ser)"; Rita Elkins; 2004
- "Naturally Raising Your HGH Levels"; Dicken C Weatherby; 2005
- "The DHEA Breakthrough"; Stephen A. Cherniske; 1998
- "DHEA: A Practical Guide"; Ray Sahelian; 1996
- National Instutites of Health MedlinePlus. Wild yam. Updated April 18, 2018.
- National Institutes of Health MedlinePlus. DHEA. Updated May 29, 2019.
- Park SG, Hwang S, Kim JS, Park KC, Kwon Y, Kim KC. The association between dehydroepiandrosterone sulfate (DHEA-S) and bone mineral density in Korean men and women. J Bone Metab. 2017;24(1):31–36. doi:10.11005/jbm.2017.24.1.31
- von Mühlen D, Laughlin GA, Kritz-Silverstein D, Bergstrom J, Bettencourt R. Effect of dehydroepiandrosterone supplementation on bone mineral density, bone markers, and body composition in older adults: the DAWN trial. Osteoporos Int. 2008;19(5):699–707. doi:10.1007/s00198-007-0520-z
- Peixoto C, Devicari Cheda JN, Nardi AE, Veras AB, Cardoso A. The effects of dehydroepiandrosterone (DHEA) in the treatment of depression and depressive symptoms in other psychiatric and medical illnesses: A systematic review. Curr Drug Targets. 2014;15(9):901-14.
- Cleveland Clinic. Prasterone, DHEA tables or capsules (Dietary supplements).
- Archer DF. Dehydroepiandrosterone intra vaginal administration for the management of postmenopausal vulvovaginal atrophy. J Steroid Biochem Mol Biol. 2015 Jan;145:139-43. doi:10.1016/j.jsbmb.2014.09.003
- Freitas RP, Lemos TM, Spyrides MH, Sousa MB. Influence of cortisol and DHEA-S on pain and other symptoms in post menopausal women with fibromyalgia. J Back Musculoskelet Rehabil. 2012;25(4):245-52. doi:10.3233/BMR-2012-0331.
- Gómez-Santos C, Hernández-Morante JJ, Tébar FJ, et al. Differential effect of oral dehydroepiandrosterone-sulfate on metabolic syndrome features in pre- and postmenopausal obese women. Clin Endocrinol (Oxf). 2012;77(4):548-54. doi:10.1111/j.1365-2265.2011.04306.x.
- Panjari M, Davis SR. DHEA for postmenopausal women: a review of the evidence. Maturitas. 2010;66(2):172-9. doi:10.1016/j.maturitas.2009.12.017
Writer Bio
Jessica Jacobs is a registered dietitian and professional writer, contributing to "Fitness Magazine" since 2003. She received a B.A. in journalism from Arizona State University and an M.S. in nutrition and food sciences from the University of Texas at Austin.