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At Healthfully, we strive to deliver objective content that is accurate and up-to-date. Our team periodically reviews articles in order to ensure content quality. The sources cited below consist of evidence from peer-reviewed journals, prominent medical organizations, academic associations, and government data.
- MedlinePlus: Blood Thinners
- "Nutrition, Metabolism and Cardiovascular Diseases"; The Effects of Polyphenols in Olive Leaves on Platelet Function; I Singh, et al.; February 2008
- "Nutrition, Metabolism and Cardiovascular Diseases"; The Effects of Polyphenols in Olive Leaves on Platelet Function; I Singh, et al.; February 2008
- "Planta Medica"; Vasodilator Effect of Olive Leaf; A. Zarzuelo, et al.; October 1991
- "Planta Medica"; Vasodilator Effect of Olive Leaf; A. Zarzuelo, et al.; October 1991
The information contained on this site is for informational purposes only, and should not be used as a substitute for the advice of a professional health care provider. Please check with the appropriate physician regarding health questions and concerns. Although we strive to deliver accurate and up-to-date information, no guarantee to that effect is made.
Interactions With Olive Leaf Extract & Blood Thinners
Many people try to control health conditions by incorporating alternative remedies into their daily routines. Herbs and supplements are typically safe, however if you take a prescription medication, be careful. Drug interactions are common, but not always well documented. For example, olive leaf extract is a popular herbal remedy used to treat a variety of conditions, however, insufficient evidence exists regarding its interactions with drugs 1. Talk to your doctor before taking olive leaf extract while on blood thinners, as research indicates an interaction is possible 12.
If you are experiencing serious medical symptoms, seek emergency treatment immediately.
Olive Leaf Extract
Most people are familiar with the health benefits of olives and olive oil, however, another part of this Mediterranean tree is also useful -- the leaf. The olive leaf and its extracts have been used medicinally and in teas for generations. In the 1800s, the olive leaf was a common treatment for malaria.
Blood Thinners
The Effect of Olive Leaf Extract on the Thyroid
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Blood thinners are used to prevent heart attacks, strokes and blood vessel clots 2. The two main types of blood thinners include anticoagulants, such as heparin and warfarin -- or Coumadin -- and antiplatelets, such as aspirin 2. Blood thinners interact with a variety of over-the-counter medications, prescription drugs, foods and supplements 2. Some of the items that cause:
- interactions include Advil
- Tylenol
- multivitamins
- garlic
- ginkgo biloba
- green tea
- vitamin K–rich foods
Olive Leaf Extract and Blood Thinners
Insufficient drug interaction evidence exists regarding olive leaf extract and blood thinners; however, care should be taken 12. Olive leaf extract has been shown to act as a vasodilator in rats 1. A vasodilator opens blood vessels and allows blood to flow more easily. In addition, another study showed that olive leaf extract inhibited platelets from sticking together during the clotting process in test tubes 1. More research is needed on human subjects to confirm these results; however, due to olive leaf extract's potential role in vasodilation and platelet activity, there may be an increased risk of bleeding if taken while on a blood thinner 1. Talk with your doctor before taking olive leaf extract 1.
Warnings
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Interactions can be dangerous, especially with blood thinners 2. If the medication is not working properly, your risk of clotting or bleeding may increase. Read packaging labels or talk with a pharmacist when choosing herbs, supplements and over-the-counter drugs. If you have any concerns about how something will react to the blood thinner you are taking, consult with your doctor.
- Interactions can be dangerous, especially with blood thinners 2.
- If you have any concerns about how something will react to the blood thinner you are taking, consult with your doctor.
Related Articles
References
- The Natural Path: Olive Leaf Extract
- MedlinePlus: Blood Thinners
- "Nutrition, Metabolism and Cardiovascular Diseases"; The Effects of Polyphenols in Olive Leaves on Platelet Function; I Singh, et al.; February 2008
- "Planta Medica"; Vasodilator Effect of Olive Leaf; A. Zarzuelo, et al.; October 1991
- Agency for Healthcare Research and Quality; Blood Thinner Pills; 2010
- Memorial Sloan Kettering Cancer Center. Olive leaf. Updated September 12, 2013.
- Wainstein J, Ganz T, Boaz M, et al. Olive leaf extract as a hypoglycemic agent in both human diabetic subjects and in rats. J Med Food. 2012;15(7):605-10. doi:10.1089/jmf.2011.0243
- Lockyer S, Rowland I, Spencer JPE, Yaqoob P, Stonehouse W. Impact of phenolic-rich olive leaf extract on blood pressure, plasma lipids and inflammatory markers: a randomised controlled trial. Eur J Nutr. 2017;56(4):1421-1432. doi:10.1007/s00394-016-1188-y
- Omar SH. Oleuropein in olive and its pharmacological effects. Sci Pharm. 2010;78(2):133-54. doi:10.3797/scipharm.0912-18
- Basch, EM, Ulbricht, C. Natural standard herb & supplement guide. New York, NY: Elsevier Health Sciences; 2016.
- RxList. Olive. Updated September 17, 2019.
- Loria, K. How to choose supplements wisely. Consumer Reports. October 30, 2019.
- Shen Y, Song SJ, Keum N, Park T. Olive leaf extract attenuates obesity in high-fat diet-fed mice by modulating the expression of molecules involved in adipogenesis and thermogenesis. Evid Based Complement Alternat Med. 2014;2014:971890. doi:10.1155/2014/971890
- El SN, Karakaya S. Olive tree (Olea europaea) leaves: potential beneficial effects on human health. Nutr Rev. 2009 Nov;67(11):632-8. doi: 10.1111/j.1753-4887.2009.00248.x.
- Omar SH. Oleuropein in olive and its pharmacological effects. Sci Pharm. 2010;78(2):133-54. doi: 10.3797/scipharm.0912-18.
- Vogel P, Kasper Machado I, Garavaglia J, et al. Polyphenols benefits of olive leaf (Olea europaea L) to human health. Nutr Hosp. 2014;31(3):1427-33. doi: 10.3305/nh.2015.31.3.8400.
Writer Bio
Debra Wolf is a freelance writer and health coach. In 2010 she co-founded Lean & Chic, which specializes in health and style makeovers. She received her training from the Institute for Integrative Nutrition and is pursuing her Master of Science in human nutrition at The University of Bridgeport.