What does fact checked mean?
At Healthfully, we strive to deliver objective content that is accurate and up-to-date. Our team periodically reviews articles in order to ensure content quality. The sources cited below consist of evidence from peer-reviewed journals, prominent medical organizations, academic associations, and government data.
- "Psychological Reports"; Caffeine's Effects on True and False Memory; S. Capek and R.K. Guenther; June 2009
- "Psychological Reports"; Caffeine's Effects on True and False Memory; S. Capek and R.K. Guenther; June 2009
- U.S. Food and Drug Administration; Medicines in My Home: Caffeine and Your Body; 2007
The information contained on this site is for informational purposes only, and should not be used as a substitute for the advice of a professional health care provider. Please check with the appropriate physician regarding health questions and concerns. Although we strive to deliver accurate and up-to-date information, no guarantee to that effect is made.
The Effects of Caffeine Drunk With Aspartame
If you are avoiding caffeine and missed your customary cup of morning coffee, you may feel tired, moody, depressed or have difficulty concentrating, which are classic symptoms of caffeine withdrawal. Aspartame, an artificial sweetener used by manufacturers to maintain the sweetness of their foods or beverages without adding additional sugar and calories, has developed a reputation over the years for causing side effects of its own. Determine how your body handles these substances individually before taking them together, if you are concerned about side effects.
About Caffeine
The U.S. Food and Drug Administration classifies caffeine as a drug and food additive. Approximately 80 percent of American adults consume 200 mg of caffeine daily; that’s equivalent to one to two 5-oz. cups of coffee. Caffeine may cause unpleasant side effects, but research has shown that mild caffeine consumption may provide neurological benefits in some adults. A study published in the June 2009 issue of “Psychology Reports” investigated the effects of caffeine on memory loss in college students 1. Researchers gave subjects either a 200-mg dose of caffeine or a 250-mg dose of a lactose placebo followed by a 30-minute hiatus and a six-word recall test. Results indicated that subjects who ingested the caffeine remembered more words than those given the placebo.
- The U.S. Food and Drug Administration classifies caffeine as a drug and food additive.
- Researchers gave subjects either a 200-mg dose of caffeine or a 250-mg dose of a lactose placebo followed by a 30-minute hiatus and a six-word recall test.
Caffeine's Side Effects
Seroquel & Caffeine
Learn More
The side effects you might experience after caffeine ingestion may vary depending on your body and the amount you consumed. People who ingest caffeine daily may become dependent and experience withdrawal symptoms, such as irritability, headache or fatigue, if they suddenly cease consumption.
About Aspartame
Aspartame, which is commercially marketed as Equal and NutraSweet, has been approved for use in more than 100 countries and is found in more than 6,000 foods worldwide. Its composition includes the chemicals aspartic acid and phenylalanine, which are held together by a methanol bond. The scientific community has conducted more than 200 scientific investigations on aspartame; however, the FDA has continued to support its use as a “general purpose sweetener in food.”
Aspartame's Side Effects
Stevia Side Effects: Nervous System & Psychological
Learn More
Mercola.com states that “aspartame accounts for more than 75 percent of the adverse reactions to food additives reported to the FDA.” The FDA compiled a list of the 90 various documented symptoms attributed to aspartame consumption. They include:
- migraine headaches
- anxiety attacks
- muscle spasms
- heart palpitations
- insomnia
- nausea
Caffeine and Aspartame
According to Mercola.com, the amino acid aspartic acid, which composes 40 percent of aspartame, elevates the level of aspartame in the blood. This chemical travels to the brain via the blood and performs as a neurotransmitter. It allows calcium and free radicals to enter brain cells that later die as a result of overstimulation; aspartame is referred to as an excitotoxin because it “excites” cells to death. Caffeine, which has side effects similar to aspartame, also stimulates brain activity and can compound the damage aspartame may cause. Taking caffeine in conjunction with aspartame may worsen side effects.
- According to Mercola.com, the amino acid aspartic acid, which composes 40 percent of aspartame, elevates the level of aspartame in the blood.
- Caffeine, which has side effects similar to aspartame, also stimulates brain activity and can compound the damage aspartame may cause.
Related Articles
References
- "Psychological Reports"; Caffeine's Effects on True and False Memory; S. Capek and R.K. Guenther; June 2009
- Johns Hopkins Medicine: Caffeine Withdrawal Recognized as a Disorder; September 2004
- Mercla.com: Aspartame is, by Far, the Most Dangerous Substance on the Market That is Added to Foods
- Meredith SE, Juliano LM, Hughes JR, Griffiths RR. Caffeine Use Disorder: A Comprehensive Review and Research Agenda. J Caffeine Res. 2013;3(3):114-130. doi:10.1089/jcr.2013.0016
- Richards G, Smith AP. A Review of Energy Drinks and Mental Health, with a Focus on Stress, Anxiety, and Depression. J Caffeine Res. 2016;6(2):49-63. doi:10.1089/jcr.2015.0033
- Brunyé TT, Mahoney CR, Rapp DN, Ditman T, Taylor HA. Caffeine enhances real-world language processing: evidence from a proofreading task. J Exp Psychol Appl. 2012;18(1):95-108. doi:10.1037/a0025851
- Koppelstaetter F, Poeppel TD, Siedentopf CM, et al. Caffeine and cognition in functional magnetic resonance imaging. J Alzheimers Dis. 2010;20 Suppl 1:S71-84. doi:10.3233/JAD-2010-1417
- Harrell PT, Juliano LM. Caffeine expectancies influence the subjective and behavioral effects of caffeine. Psychopharmacology (Berl). 2009;207(2):335-42. doi:10.1007/s00213-009-1658-5
- Lucas M, O'reilly EJ, Pan A, et al. Coffee, caffeine, and risk of completed suicide: results from three prospective cohorts of American adults. World J Biol Psychiatry. 2014;15(5):377-86. doi:10.3109/15622975.2013.795243
- Abdel-Hady H, Nasef N, Shabaan AE, Nour I. Caffeine therapy in preterm infants. World J Clin Pediatr. 2015;4(4):81-93. doi:10.5409/wjcp.v4.i4.81
- American Psychiatric Association. Diagnostic and Statistical Manual of Mental Disorders. 5th edition. Washington DC; 2013.
- Turnbull D, Rodricks JV, Mariano GF, Chowdhury F. Caffeine and cardiovascular health. Regul Toxicol Pharmacol. 2017;89:165-185. doi:10.1016/j.yrtph.2017.07.025
- Centers for Disease Control and Prevention. Alcohol and Caffeine. Updated October 23, 2018.
- Alsunni AA. Energy Drink Consumption: Beneficial and Adverse Health Effects. Int J Health Sci (Qassim). 2015;9(4):468-474.
- Lyngsø J, Ramlau-Hansen CH, Bay B, Ingerslev HJ, Hulman A, Kesmodel US. Association between coffee or caffeine consumption and fecundity and fertility: a systematic review and dose-response meta-analysis. Clin Epidemiol. 2017;9:699-719. doi:10.2147/CLEP.S146496
- U.S. Food and Drug Administration. Pure and Highly Concentrated Caffeine. Updated September 21, 2018.
- National Institute on Drug Abuse. Drugs, Brains, and Behavior: The Science of Addiction. Updated July 2018.
Writer Bio
Meka Jones, from Cherokee, Ala., began writing in 2009. She is a faculty member at Shelton State Community College and has written for "Shoals Woman Magazine" and various online publications. Jones is pursuing a Ph.D. in exercise physiology at the University of Alabama and holds Master of Arts and Bachelor of Science degrees in physical education from the University of North Alabama.