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- National Institute of Neurological Disorders and Stroke; NINDS Cerebral Hypoxia Information Page; October 2010
- "Journal of Clinical Pathology Supplement"; Hypoxia in the Newborn Infant; E. O. Reynolds; 1977
- "Journal of Clinical Pathology Supplement"; Hypoxia in the Newborn Infant; E. O. Reynolds; 1977
- Laeknabladid; Birth Asphyxia and Hypoxic Ischemic Encephalopathy, Incidence and Obstetric Risk Factors; September 2007
- Laeknabladid; Birth Asphyxia and Hypoxic Ischemic Encephalopathy, Incidence and Obstetric Risk Factors; September 2007
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Hypoxia of a Newborn
In the moments during and immediately after birth, the delivery room medical staff is alert to the possibility of hypoxia in the newborn. This condition, caused by a lack of oxygen to the brain, can be extremely dangerous for the baby and requires a rapid medical response to detect and prevent complications that could occur. A thorough assessment of the known risk factors prior to birth can help doctors and pregnant women prepare in advance for the possibility of hypoxia and take steps to prevent it.
Hypoxia
Hypoxia in a newborn involves any condition that reduces the supply of oxygen to the brain 1. A common cause is a problem with the baby's respiratory system that prevents the newborn from getting enough oxygen. If the newborn does not take a breath soon after being born, hypoxia can develop rapidly. A baby born with his umbilical cord wrapped around his neck can also develop hypoxia as a result of the cord choking off blood supply to the brain. In other cases, an underlying medical problem causes hypoxia that develops more slowly, and the infant's blood levels of oxygen decline over the course of a few hours or days until the situation is urgent. If not treated, hypoxia can lead to brain damage or death.
- Hypoxia in a newborn involves any condition that reduces the supply of oxygen to the brain 1.
- In other cases, an underlying medical problem causes hypoxia that develops more slowly, and the infant's blood levels of oxygen decline over the course of a few hours or days until the situation is urgent.
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Hypoxia in a newborn is considered a medical emergency. After birth, the delivery room doctor or nurse assesses the newborn for typical responses, behavior and physical condition. If the baby displays signs of hypoxia, such as abnormal coloring or behavioral problems, the immediate response is to attempt to restore oxygen flow to the brain and prevent any further brain damage. This can only be done if the reason for the hypoxia is clear, so the medical staff might have to subject the baby to a range of tests, including blood tests, ultrasounds, blood pressure and heartbeat monitoring and X-rays to determine the source of the problem so that it can be corrected as soon as possible.
- Hypoxia in a newborn is considered a medical emergency.
- If the baby displays signs of hypoxia, such as abnormal coloring or behavioral problems, the immediate response is to attempt to restore oxygen flow to the brain and prevent any further brain damage.
Prevention
Babies who are born under conditions that might lead to hypoxia are watched closely and preventative actions are taken when needed. During birth, the doctor or midwife typically checks the umbilical cord for any signs of knots or looping around the neck and may physically try to adjust it as the baby is being born to prevent problems. Clearing the airway after birth is another way to prevent hypoxia, especially if there is a possibility that the baby inhaled meconium, contents of the digestive tract that some babies release into their amniotic fluid shortly before birth. Fetal heart rate monitoring before birth can also help prevent hypoxia since it can indicate the need for an immediate Cesarean section.
- Babies who are born under conditions that might lead to hypoxia are watched closely and preventative actions are taken when needed.
- During birth, the doctor or midwife typically checks the umbilical cord for any signs of knots or looping around the neck and may physically try to adjust it as the baby is being born to prevent problems.
Outlook
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If the newborn is immediately treated after birth and the lack of oxygen is corrected quickly, the baby may be able to make a full recovery. The longer the period of time the brain is without oxygen, the more complications will result. Damage caused by hypoxia is irreversible, so a baby who develops brain damage in this way is likely to experience lifelong effects. Potential complications include cerebral palsy, learning disabilities and mental retardation.
- If the newborn is immediately treated after birth and the lack of oxygen is corrected quickly, the baby may be able to make a full recovery.
- Damage caused by hypoxia is irreversible, so a baby who develops brain damage in this way is likely to experience lifelong effects.
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References
- "Journal of Clinical Pathology Supplement"; Hypoxia in the Newborn Infant; E. O. Reynolds; 1977
- Lippincott's Nursing Center; Hypoxia in the Term Newborn; A. J. Rohan and S. G. Golombek; March 2009
- Laeknabladid; Birth Asphyxia and Hypoxic Ischemic Encephalopathy, Incidence and Obstetric Risk Factors; September 2007
- "The New England Journal of Medicine"; Whole-body Hypothermia for Neonates with Hypoxic-Ischemic Encephalopathy; S. Shankaran, et al.; October 2005
- Sarkar M, Niranjan N, Banyal PK. Mechanisms of hypoxemia. Lung India. 2017;34(1):47-60. doi:10.4103/0970-2113.197116
- Pittman RN. Regulation of Tissue Oxygenation. San Rafael (CA): Morgan & Claypool Life Sciences; 2011. Chapter 7, Oxygen Transport in Normal and Pathological Situations: Defects and Compensations.
- Merck Manual. Consumer Version. Respiratory Failure. Revised March 2018.
- Adeyinka A, Kondamudi NP. Cyanosis. [Updated 2019 Jun 3]. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2019 Jan-.
- Bickler PE, Feiner JR, Lipnick MS, Batchelder P, Macleod DB, Severinghaus JW. Effects of Acute, Profound Hypoxia on Healthy Humans: Implications for Safety of Tests Evaluating Pulse Oximetry or Tissue Oximetry Performance. Anesth Analg. 2017;124(1):146-153. doi:10.1213/ANE.0000000000001421
- Federal Aviation Administration. Beware of Hypoxia. Modified July 21, 2015.
- Rose JJ, Wang L, Xu Q, et al. Carbon Monoxide Poisoning: Pathogenesis, Management, and Future Directions of Therapy. Am J Respir Crit Care Med. 2017;195(5):596-606. doi:10.1164/rccm.201606-1275CI++
- Merck Manual Professional Version. Oxygen Desaturation (Hypoxia). Revised April 2019.
- Kasper, Dennis L.., Anthony S. Fauci, and Stephen L.. Hauser. Harrison's Principles of Internal Medicine. New York: Mc Graw Hill education, 2015. Print.
Writer Bio
Bridget Coila specializes in health, nutrition, pregnancy, pet and parenting topics. Her articles have appeared in Oxygen, American Fitness and on various websites. Coila has a Bachelor of Science in cell and molecular biology from the University of Cincinnati and more than 10 years of medical research experience.