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Vitamin E may produce therapeutic effects if you have heart and liver disease, MayoClinic.com reports 1. High doses of vitamin E however may cause bleeding, cerebral hemorrhage or stroke, and bruising under the skin 1. You need to consult your doctor about your intention to take vitamin E because it could cause adverse effects with other medications, such as blood thinners 1. While most people take vitamin E by mouth, you can use it as a suppository rectally and vaginally to help with minor irritation or dryness 1. No matter how you use vitamin E, it has the potential to cause side effects 1.
When you use vitamin E suppositories, you may feel sick to your stomach and you may vomit, Drugs.com reports 1. This overwhelming feeling of an upset stomach, categorized as a non-serious side effect, typically ends as your body becomes used to the extra infusion of vitamin E in your system 1. If it troubles you, you can take some over-the-counter anti-nausea medication to quell it. Talk with your doctor for help if nausea and vomiting appear severe or do not stop.
Vitamin K and an Allergy or Rash
Diarrhea, like nausea, may occur as your body attempts to adjust to taking vitamin E suppositories, Drugs.com indicates 1. You may need to use the bathroom frequently and will begin to notice your stools become watery. You may feel cramps with any form of diarrhea, although when you use vitamin E suppositories, you should have mild loose stools and cramps, not severe forms of these adverse effects 1. This should stop after the first few days of taking this vitamin. Your stomach may be sensitive to new medications and vitamin supplements. You also may get abdominal cramping as a separate side effect without diarrhea, Drugs.com indicates 1. If it continues, speak to your doctor.
Headaches sometimes occur as less-than-serious side effects when you first take vitamin E, Drugs.com indicates 1. Pain such as this may occur in mild form and should cease as you become accustomed to using vitamin E suppositories 1.
Does Rubbing Vitamin E on the Face Help Wrinkles?
You may find it difficult to focus your eyes properly when you begin using vitamin E, Drugs.com indicates 1. This temporary and non-serious side effect may occur when viewing distant or near objects, but it should clear up as you continue using the suppositories.
You may get a mild rash when you begin using vitamin E suppositories 1. Your skin may become reddened and it may itch. If it does not go away, call your doctor. If you become short of breath with the rash, seek emergency treatment as it may be a hypersensitivity reaction to the vitamin.
- You may get a mild rash when you begin using vitamin E suppositories 1.
- If you become short of breath with the rash, seek emergency treatment as it may be a hypersensitivity reaction to the vitamin.
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- Drugs.com: Vitamin E
- MedlinePlus: Vitamin E
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- Salehpour A, Hosseinpanah F, Shidfar F, et al. A 12-week double-blind randomized clinical trial of vitamin D₃ supplementation on body fat mass in healthy overweight and obese women. Nutr J. 2012;11:78. doi:10.1186/1475-2891-11-78
- Carrillo AE, Flynn MG, Pinkston C, et al. Impact of vitamin D supplementation during a resistance training intervention on body composition, muscle function, and glucose tolerance in overweight and obese adults. Clin Nutr. 2013;32(3):375-381. doi:10.1016/j.clnu.2012.08.014
- Marcinowska-Suchowierska E, Kupisz-Urbańska M, Łukaszkiewicz J, Płudowski P, Jones G. Vitamin D Toxicity-A Clinical Perspective. Front Endocrinol. 2018;9:550. doi:10.3389/fendo.2018.00550
- Ross AC, Manson JE, Abrams SA, et al. The 2011 report on dietary reference intakes for calcium and vitamin D from the Institute of Medicine: what clinicians need to know. J Clin Endocrinol Metab. 2011;96(1):53-58. doi:10.1210/jc.2010-2704
- Bouillon R, Van Schoor NM, Gielen E, et al. Optimal vitamin D status: a critical analysis on the basis of evidence-based medicine. J Clin Endocrinol Metab. 2013;98(8):E1283-E1304. doi:10.1210/jc.2013-1195
- American Academy of Dermatology. Position Statement of Vitamin D. 2010.
- Taksler GB, Cutler DM, Giovannucci E, Keating NL. Vitamin D deficiency in minority populations. Public Health Nutr. 2015;18(3):379-391. doi:10.1017/S1368980014000457
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- Cannell JJ, Vieth R, Umhau JC, et al. Epidemic Influenza and Vitamin D. Epidemiol Infect. 2006; 134:1129-40.
- Carrillo AE1, Flynn MG, Pinkston C, Markofski MM, Jiang Y, Donkin SS, Teegarden D. Impact of Vitamin D Supplementation During a Resistance Training Intervention on Body Composition, Muscle Function, and Glucose Tolerance in Overweight and Obese Adults. Clin Nutr. 2013 Jun;32(3):375-81. doi: 10.1016/j.clnu.2012.08.014. Epub 2012 Aug 31.
- Ginde AA, Mansbach JM, Camargo CA, Jr. Association Between Serum 25-Hydroxyvitamin D Level and Upper Respiratory Tract Infection in the Third National Health and Nutrition Examination Survey. Arch Intern Med. 2009; 169:384-90.
- Giovannucci E, Liu Y, Hollis BW, Rimm EB. 25-hydroxyvitamin D and Risk of Myocardial Infarction in Men: a Prospective Study. Arch Intern Med. 2008; 168:1174-80.
- Gorham ED, Garland CF, Garland FC, Grant WB, Mohr SB, Lipkin M, Newmark HL, Giovannucci E, Wei M, Holick MF. Optimal Vitamin D Status for Colorectal Cancer Prevention: a Quantitative Meta-analysis. Am J Prev Med. 2007 Mar;32(3):210-6.
- Heaney, Robert P. “The Vitamin D Requirement in Health and Disease.” The Journal of Steroid Biochemistry & Molecular Biology 97 (2005):13-9.
- Holick MF. Vitamin D. In: Shils M, Olson J, Shike M, Ross AC, ed. Modern Nutrition in Health and Disease, 9th ed. Baltimore: Williams and Wilkins, 1999.
- National Institutes of Health Office of Dietary Supplements. Vitamin D: Dietary Supplement Fact Sheet. University of Ottawa Evidence-based Practice Center. Effectiveness and Safety of Vitamin D in Relation to Bone Health. Agency for Healthcare Research and Quality. Aug 2007: 07-E013.
- Salehpour A1, Hosseinpanah F, Shidfar F, Vafa M, Razaghi M, Dehghani S, Hoshiarrad A, Gohari M. A 12-week Double-blind Randomized Clinical Trial of Vitamin D₃ Supplementation on Body Fat Mass in Healthy Overweight and Obese Women. Nutr J. 2012 Sep 22;11:78. doi: 10.1186/1475-2891-11-78.
- Urashima M, Segawa T, Okazaki M, Kurihara M, Wada Y, Ida H. Randomized Trial of Vitamin D Supplementation to Prevent Seasonal Influenza A in Schoolchildren. Am J Clin Nutr. 2010 91:1255-60. Epub 2010 Mar 10.
- Wilkins, Consuelo H. and Yvette I. Sheline, et al. “Vitamin D Deficiency Is Associated with Low Mood and Worse Cognitive Performance in Older Adults.” American Journal of Geriatric Psychiatry 14 (2006): 1032-40.
Carole Anne Tomlinson is a registered nurse with experience in rehabilitation, nutrition, chemical dependency, diabetes and health problems related to the elderly. Tomlinson holds a Bachelor of Arts in criminal justice and is presently working on her master's degree in nursing. Her screenplays have been viewed by Merchant Ivory, Angela Lansbury and Steven King's associates.