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Information on the Japanese Two Day Diet Pills

By Shelley Moore ; Updated July 18, 2017

The U.S. Food and Drug Administration has issued a warning against a weight loss product called 2-Day Diet. Various websites sell these pills, referring to them with names such as Two-Day Diet Japan Linghzi Slimming Formula, but the name on the box in English simply reads "2-Day Diet." The pills have been determined to contain sibutramine, a drug that is no longer available in the United States because it can cause dangerous side effects.

Claimed Benefits

The Japanese two day diet pills, only available online, are claimed to stop your body from digesting fat, to suppress your appetite and to boost metabolism, as noted by the Diets in Review website. The supplement may actually work for weight loss because sibutramine is an appetite suppressant.

Listed Ingredients

Ingredients listed on the two day diet pills include dioscoreae, ebony, fox-nut, lingzhi, tuckahoe, Semen pruni, wheat germ and an item called "nature substance." Sibutramine is not declared as an ingredient on this product's labeling.


In December 2008 and January 2009, the FDA issued advisories warning consumers not to use numerous weight loss products that were found to be tainted with prescription drugs. The list included products called "2-Day Diet" and "2-Day Diet Advance" because both contain sibutramine. In the United States, sibutramine was previously sold as the prescription medication Meridia, used to treat obesity. The FDA advises consumers who have used the 2-Day Diet supplement to stop taking it and consult a health care professional.


Sibutramine is no longer available in the United States because the drug is connected with increased risk of heart attack and stroke. Sibutramine can cause increased blood pressure, heart palpitations, fast heart rate and seizures, notes an FDA consumer information publication.


People with certain health problems are at increased risk of serious negative effects from sibutramine, notes the FDA. These include individuals with a history of heart disease, stroke or hypertension, particularly if their hypertension is not well-controlled. If you have a history of seizures, or have severe liver problems or narrow-angle glaucoma, you're also at greater risk of serious effects. If you're prone to abnormal bleeding or take medications that increase the risk of bleeding, you may not be able to safely use substances containing sibutramine. Sibutramine also interacts with many other drugs, which can cause hazardous effects.

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