Side Effects of Caltrate Plus D Calcium Pills

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Caltrate plus D, also called Caltrate 600+D, is a nutritional supplement that contains both calcium and vitamin D. In conjunction, these nutrients help maintain bone strength in people with fragile bones due to low calcium or vitamin D levels. This over-the-counter supplement should be taken twice daily with food or as recommended by a doctor. People should be aware of the side effects of Caltrate plus D calcium pills before beginning to use to type of treatment.


Treatment with Caltrate plus D may cause constipation as a side effect in certain people, RxList reports. Constipation is characterized by difficult, painful or absent bowel movements. People who experience constipation may also develop abdominal cramping, bloating or discomfort. If this side effect becomes severe or persistent, affected people should seek care from a medical professional.

Nausea or Vomiting

After taking a dose of this nutritional supplement, people may become nauseous or may begin to vomit, warns. These upset stomach side effects are unpleasant and may continue for several hours following treatment with Caltrate plus D. People should avoid taking this supplement on an empty stomach to limit the development or severity of upset stomach side effects.

Diminished Appetite

People who develop constipation, nausea or vomiting following treatment with Caltrate plus D may also experience a diminished appetite. Loss of appetite may cause people to eat less food during the day, which can lead to weight loss in certain people.


Improper or excessive use of Caltrate plus D calcium pills may cause people to develop hypercalcemia, a condition in which the body has unusually high levels of calcium. Side effects associated with hypercalcemia include increased urination, heart rate irregularities, fatigue, weakness, headache, muscle pain or increased thirst, reports. If these side effects arise, affected patients should seek prompt care from a medical professional.