What Are the Dangers of Nicotine Lozenges?
Nicotine lozenges are an orally-administered smoking cessation aid indicated to help people stop smoking tobacco cigarettes. This treatment is administered as a lozenge, which slowly dissolves within the mouth. Nicotine lozenges work by helping to control the side effects of nicotine withdrawal. People should be aware of the potential dangers of nicotine lozenges before beginning to use this treatment.
Side Effects
The primary side effects of lozenge use include sore throat discomfort or heartburn, a painful burning sensation felt at the top of the stomach, according to PubMed Health. People who develop severe side effects, such as heart rate irregularities or unusual mouth sores, should seek care from a medical professional as soon as possible.
Overdose
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Improper use of nicotine lozenges may put people in danger of developing a nicotine overdose. Overdose symptoms require immediate medical attention and include dizziness, weakness, diarrhea, nausea, vomiting and a rapid heart rate, MedlinePlus warns.
Withdrawal
Prolonged use of nicotine lozenges may elevate a person's risk of experiencing withdrawal symptoms upon ending treatment. Symptoms of withdrawal, such as nervousness, headache, irritability or tobacco cravings, can be uncomfortable, RxList reports. People should consult a physician to determine the best way to limit the risk or severity of withdrawal symptoms.
Medication Interactions
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People who take certain types of antidepressant medications, such as bupropion, or asthma medications, such as theophylline, may be at risk of experiencing severe side effects if these drugs are used in conjunction with nicotine lozenges, according to Drugs.com. To avoid these complications, people should review all current medication use with a physician before taking nicotine lozenges.
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References
- Drugs.com: Nicotine Lozenges
- RxList: Nicotine (Polacrilex)
- MedlinePlus: Nicotine Lozenges
- Wadgave U, Nagesh L. Nicotine Replacement Therapy: An Overview. Int J Health Sci (Qassim). 2016;10(3):425-35.
- Dautzenberg B, Nides M, Kienzler JL, Callens A. Pharmacokinetics, safety and efficacy from randomized controlled trials of 1 and 2 mg nicotine bitartrate lozenges (Nicotinell). BMC Clin Pharmacol. 2007;7:11. doi:10.1186/1472-6904-7-11
- Sukhija M, Srivastava R, Kaushik A. Pharmacokinetic characterization of three novel 4-mg nicotine lozenges . Int J Clin Pharmacol Ther. 2018;56(3):113-119. doi:10.5414/CP203097
- Baker TB, Piper ME, Mccarthy DE, et al. Time to first cigarette in the morning as an index of ability to quit smoking: implications for nicotine dependence. Nicotine Tob Res. 2007;9 Suppl 4:S555-70. doi:10.1080/14622200701673480
- Pack QR, Jorenby DE, Fiore MC, et al. A comparison of the nicotine lozenge and nicotine gum: an effectiveness randomized controlled trial. WMJ. 2008;107(5):237-43.
- Mills EJ, Wu P, Lockhart I, Wilson K, Ebbert JO. Adverse events associated with nicotine replacement therapy (NRT) for smoking cessation. A systematic review and meta-analysis of one hundred and twenty studies involving 177,390 individuals. Tob Induc Dis. 2010;8:8. doi:10.1186/1617-9625-8-8
- National Institutes of Health. Nicotine Lozenges. Updated July 15, 2016.
- GlaxoSmithKline. Frequently Asked Questions About Nicorette 2016.
- GlaxoSmithKline. Nicotine Lozenges 2016.
Writer Bio
Rae Uddin has worked as a freelance writer and editor since 2004. She specializes in scientific journalism and medical and technical writing. Her work has appeared in various online publications. Uddin earned her Master of Science in integrated biomedical sciences with an emphasis in molecular and cellular biochemistry from the University of Kentucky College of Medicine.