Vitamin & Mineral Deficiencies Associated With Lupus
Vitamin deficiencies tend to go hand in hand with many chronic diseases and conditions, such as lupus. Vitamins and minerals are essential nutrients that your body needs to function properly, and without the right balance of vitamins and nutrients, deficiencies occur. These deficiencies can cause their own symptoms or make the systems of your condition worse. If you suffer from lupus, the main vitamin deficiencies you and your physician should monitor are vitamins D and B-12.
Lupus
Lupus, or systemic lupus erythematosus, is an autoimmune disease where your body’s immune system has short-circuited. Your immune system is designed to fight off and attack foreign bodies such as bacteria and viruses. However, in lupus and other autoimmune diseases, your immune system attacks the healthy cells and tissues within your body. According to the National Institutes of Health, systems of lupus can include joint swelling and pain, muscle pain, a fever with an unknown cause and rashes that are known for the trademark butterfly rash that appears on the face in lupus patients.
- Lupus, or systemic lupus erythematosus, is an autoimmune disease where your body’s immune system has short-circuited.
Vitamin D
Do Lupus Patients Usually Have Low Vitamin D & Potassium?
Learn More
Vitamin D is a fat-soluble nutrient that is responsible for bone health and has been linked to the possible prevention of autoimmune diseases and their symptoms. It can be found in some food sources, such as fortified milk and salmon, but can also be made when your skin is exposed to the ultraviolet B rays from the sun. Vitamin D deficiency is common and is seen frequently in patients with lupus. A 2001 study published in “Lupus” shows that most lupus patients have a vitamin D deficiency and that the deficiency seems to be associated with higher disease activity. Researchers suggest treating the vitamin D deficiency can reduce symptoms and disease activity.
- Vitamin D is a fat-soluble nutrient that is responsible for bone health and has been linked to the possible prevention of autoimmune diseases and their symptoms.
- A 2001 study published in “Lupus” shows that most lupus patients have a vitamin D deficiency and that the deficiency seems to be associated with higher disease activity.
Vitamin B-12
Vitamin B-12 is one of the many nutrients that make up what is known as the B-complex of vitamins. Vitamin B-12 is responsible for keeping the nerve and blood cells healthy and aids in the construction of DNA and genetic material. it is essential in preventing anemia, something that is often seen in people with lupus and contributes to the tired and weak feelings they suffer from. A 2004 study published in “Rheumatology International” looked at the incidences of anemia and serum vitamin B-12 deficiencies in patients with rheumatoid arthritis, psoriatic arthritis and systemic lupus erythematosus and found that it was much higher in patients suffering from these diseases and that such patients should be monitored for vitamin B-12 deficiency.
- Vitamin B-12 is one of the many nutrients that make up what is known as the B-complex of vitamins.
- A 2004 study published in “Rheumatology International” looked at the incidences of anemia and serum vitamin B-12 deficiencies in patients with rheumatoid arthritis, psoriatic arthritis and systemic lupus erythematosus and found that it was much higher in patients suffering from these diseases and that such patients should be monitored for vitamin B-12 deficiency.
Minerals and Lupus
Does Vitamin B-12 Cause OCD to Be Worse?
Learn More
Minerals, like vitamins are essential for your body to function in many ways. Minerals include calcium, phosphorus, magnesium, potassium, sodium, chloride, sulfur, iron, copper, iodine, zinc, manganese, cobalt, fluoride and selenium. A 2005 study published in “Clinical Rheumatology” looked at the levels of zinc, copper, magnesium, manganese and iron in patients with lupus. The researchers believe that the changes in a lupus patient's levels may not be a reason for the disease as originally thought, but a consequence of having the disease.
- Minerals, like vitamins are essential for your body to function in many ways.
- The researchers believe that the changes in a lupus patient's levels may not be a reason for the disease as originally thought, but a consequence of having the disease.
Considerations
With most autoimmune diseases comes the risk of vitamin deficiencies, and you and your physician should be aware of these and make sure you are tested on a regular basis. Your physician can test your blood levels, and if a deficiency is detected, he can establish a supplement plan to best keep your levels within the normal ranges. Some of the medications you take to treat lupus, such as corticosteroids like prednisone, can affect how your body absorbs and uses nutrients, so supplementation would need to be adjusted with that information considered.
Related Articles
References
- Medline Plus: Lupus
- Office of Dietary Supplements: Vitamin D
- “Lupus”; Vitamin D Deficiency and its Association with Disease Activity in New Cases of Systemic Lupus Erythematosus; Z.S. Bonakdar et al.; June 16, 2011
- Office of Dietary Supplements: Vitamin B-12
- “Rheumatology International”; Anemia, Serum Vitamin B-12, and Folic Acid in Patients with Rheumatoid Arthritis, Psoriatic Arthritis, and Systemic Lupus Erythematosus; R. Segal et al.; January 2004
- “Clinical Rheumatology”; Trace Elements and Some Extracellular Antioxidant Proteins Levels in Serum of Patients With Systemic Lupus Erythematosus; A. Yilmaz et al.; August 2005
- Centers for Disease Control and Prevention. Systemic lupus erythematosus (SLE). Updated October 17, 2018.
- Lupus Foundation of America. Lupus facts and statistics. Updated October 6, 2016.
- Centers for Disease Control and Prevention. Lupus in women. Updated October 17, 2018.
- Maidhof W, Hilas O. Lupus: an overview of the disease and management options. P T. 2012;37(4):240-9.
- Lupus Foundation of America. Lupus facts and statistics. Updated October 6, 2016.
- Lupus Foundation of America. About cutaneous lupus. Updated July 12, 2013.
- Barbhaiya M, Costenbader KH. Environmental exposures and the development of systemic lupus erythematosus. Curr Opin Rheumatol. 2016;28(5):497-505. doi:10.1097/BOR.0000000000000318
- Grönhagen CM, Nyberg F. Cutaneous lupus erythematosus: An update. Indian Dermatol Online J. 2014;5(1):7-13. doi:10.4103/2229-5178.126020
- Johns Hopkins Lupus Center. Lupus-specific skin disease and skin problems.
- Centers for Disease Control and Prevention. Lupus symptoms. Updated October 17, 2018.
- Harley JB, Chen X, Pujato M, et al. Transcription factors operate across disease loci, with EBNA2 implicated in autoimmunity. Nat Genet. 2018;50(5):699-707. doi:10.1038/s41588-018-0102-3
- Centers for Disease Control and Prevention. Diagnosing and treating lupus. Updated October 17, 2018.
- Lupus Foundation of America. Medications used to treat lupus. Updated July 12, 2013.
- Navarrete-navarrete N, Peralta-ramírez MI, Sabio-sánchez JM, et al. Efficacy of cognitive behavioural therapy for the treatment of chronic stress in patients with lupus erythematosus: a randomized controlled trial. Psychother Psychosom. 2010;79(2):107-15. doi:10.1159/000276370
- Greco CM, Nakajima C, Manzi S. Updated review of complementary and alternative medicine treatments for systemic lupus erythematosus. Curr Rheumatol Rep. 2013;15(11):378. doi:10.1007/s11926-013-0378-3
- Lupus Foundation of America. Smoking and lupus: It's never too late to quit.
- Zhang L, Fu T, Yin R, Zhang Q, Shen B. Prevalence of depression and anxiety in systemic lupus erythematosus: a systematic review and meta-analysis. BMC Psychiatry. 2017;17(1):70. doi:10.1186/s12888-017-1234-1
- Olesińska M, Saletra A. Quality of life in systemic lupus erythematosus and its measurement. Reumatologia. 2018;56(1):45-54. doi:10.5114/reum.2018.74750
- Maidhof W, Hilas O. Lupus: an overview of the disease and management options. P T. 2012;37(4):240-9.
- Lupus Foundation of America. How Lupus Affects the Skin.
Resources
Writer Bio
Deborah Lundin is a professional writer with more than 20 years of experience in the medical field and as a small business owner. She studied medical science and sociology at Northern Illinois University. Her passions and interests include fitness, health, healthy eating, children and pets.