The Negative Side Effects of Black Cohosh & Dong Quai
Herbalists have used both black cohosh and dong quai medicinally for centuries. Both herbs purportedly relieve gynecologic ailments ranging from symptoms of menopause to painful menstruation. Researchers believe that the plants contain estrogen-like properties that help replace the decreasing hormones in conditions such as menopause. While black cohosh and dong quai may have many benefits, you must also weigh the negative effects associated with ingesting these herbs. Always consult your physician before use of any herbal treatment.
Abortifacient Properties
Most researchers warn against the use of both black cohosh and dong quai during pregnancy. The American Academy of Family Physicians explains that midwives have traditionally used the herbs to induce labor or to induce an abortion. Dong quai stimulates the uterus and helps to coordinate and strengthen contractions. Properties in black cohosh help the cervix to relax and open. Both of these herbs can cause a miscarriage or induce pre-term labor in pregnant women. You should never use these herbs during pregnancy or labor without a physician’s supervision.
- Most researchers warn against the use of both black cohosh and dong quai during pregnancy.
Drug Interactions
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Herbs with estrogenic effects can often lessen the effects of hormone-based medications such as birth control pills, estrogen, progesterone, tamoxifen and raloxifene. Dong quai may also interfere with anticoagulant medications, increasing the risk of bleeding and bruising and may interact with other herbs, including feverfew, Chinese skullcap, turmeric, licorice, ginseng, ginger, garlic and ginkgo, according to the University of Maryland Medical Center. Using dong quai with St. Johns wort can increase your sensitivity to sunlight. There are no known interactions between black cohosh and prescription medications.
- Herbs with estrogenic effects can often lessen the effects of hormone-based medications such as birth control pills, estrogen, progesterone, tamoxifen and raloxifene.
- Dong quai may also interfere with anticoagulant medications, increasing the risk of bleeding and bruising and may interact with other herbs, including feverfew, Chinese skullcap, turmeric, licorice, ginseng, ginger, garlic and ginkgo, according to the University of Maryland Medical Center.
Side Effects
Taking black cohosh in recommended doses does not seem to cause side effects. However, large doses of the herb may cause headaches, abdominal pain, tremors, vision problems, vomiting, weight gain, slow heart rate and joint pain. There have been a few reported cases of liver toxicity after taking black cohosh, but there is insufficient evidence to prove the two incidents were related. MedlinePlus.com warns that high doses of dong quai may increase your sensitivity to the sun, causing skin inflammation. You should avoid sunlight or use sunscreen while using dong quai.
- Taking black cohosh in recommended doses does not seem to cause side effects.
- There have been a few reported cases of liver toxicity after taking black cohosh, but there is insufficient evidence to prove the two incidents were related.
Hormone-Related Disorders
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The estrogen-like properties in black cohosh and dong quai may affect certain hormone-related conditions such as ovarian cancer, uterine cancer, breast cancer, prostate cancer and endometriosis. Researchers are conducting clinical trials to see if black cohosh stimulates or inhibits the growth of breast cancer cells. The National Institutes of Health explains that women with a history of breast cancer, or those with a familial history of the disease, should avoid using black cohosh unless under the supervision of a physician. If you have any of these conditions, you should avoid taking these supplements. There is no known connection between dong quai and breast cancer.
- The estrogen-like properties in black cohosh and dong quai may affect certain hormone-related conditions such as ovarian cancer, uterine cancer, breast cancer, prostate cancer and endometriosis.
- The National Institutes of Health explains that women with a history of breast cancer, or those with a familial history of the disease, should avoid using black cohosh unless under the supervision of a physician.
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References
- Drugs.com: Dong Quai
- MedlinePlus.com: Dong Quai
- American Academy of Family Physicians: American Academy of Family Physicians: Methods of Cervical Ripening and Induction
- University of Maryland Medical Center: Black Cohosh
- Milton S. Hershey Medical Center, Penn State Hershey. Dong quai. Reviewed March 25, 2015.
- Botanical Online. Properties of Dong Quai. Updated March 19, 2019.
- Chao WW, Lin BF. Bioactivities of Major Constituents Isolated From Angelica Sinensis (Danggui). Chin Med. 2011;6:29. doi:10.1186/1749-8546-6-29
- Wen Y, Li J, Tan Y, et al. Angelica Sinensis Polysaccharides Stimulated UDP-sugar Synthase Genes Through Promoting Gene Expression of IGF-1 and IGF1R in Chondrocytes: Promoting Anti-Osteoarthritic Activity. PLoS One. 2014;9(9):e107024. doi:10.1371/journal.pone.0107024
- Zhuang C, Wang Y, Zhang Y, Xu N. Oxidative stress in osteoarthritis and antioxidant effect of polysaccharide from angelica sinensis. Int J Biol Macromol. 2018;115:281–286. doi:10.1016/j.ijbiomac.2018.04.083
- CancerNetwork at Oncology Online. Dong Quai (Angelica sinensis). Published January 20, 2011.
- Memorial Sloan Kettering Cancer Center. Dong Quai. Updated February 14, 2019.
- Yue GG, Wong LS, Leung HW, et al. Is Danggui Safe to be Taken by Breast Cancer Patients?-A Skepticism Finally Answered by Comprehensive Preclinical Evidence. Front Pharmacol. 2019;10:706. Published 2019 Jun 25. doi:10.3389/fphar.2019.00706
- MedlinePlus, National Institutes of Health U.S. National Library of Medicine. Dong Quai. Reviewed July 24, 2019.
Writer Bio
Based in Florida, Martina McAtee has been writing health and fitness articles since 2003. She attended Keiser University, graduating with an Associate of Science in nursing. McAtee is currently working toward a master's degree in nursing from Florida Atlantic University.