Symptoms of an Iodine Allergy
Iodine is a mineral used topically for antibacterial purposes or intravenously as a component of radiological contrast agents. Iodine is necessary to support healthy thyroid functioning. Some people, however, are highly sensitive to this mineral and exhibit symptoms of an iodine allergy that will progress with each additional exposure. According to the University of California, San Francisco, these symptoms will exhibit within two hours of exposure 1.
Skin Problems
Symptoms of an iodine allergy commonly present on the skin. With or without a visible rash, an itching sensation, or pruritis, may develop immediately after iodine exposure or injection. Red, raised rashes can develop anywhere on the body and can progress quickly to a generalized reaction of hives, or painful red welts usually on the torso.
Face and Lips
Symptoms of a Ham Allergy
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An early ominous sign of iodine allergy is the tingling of the lips, possibly progressing to the entire face, according to Cleveland Clinic 2. Angioedema refers to a generalized swelling underneath the skin and is prominent around the eyes, tongue and lips. Due to the potential for tracheal constriction, angioedema can quickly lead to a life-threatening situation.
Respiratory
Rhinitis, or a runny nose, may signal an impending allergic reaction. Indicative of a serious allergy to intravenous exposure of iodine, rhinitis may precede development of a wheeze, or a whining sound with each breath. This wheezing sound is created by the spasms of the bronchioles, or main breathing tubes, due to a massive histamine release from the allergy response.
Gastrointestinal
Itchy Skin From Iodine Supplements
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Vomiting and diarrhea can be seen with an iodine allergy. Vomiting, diarrhea and stomach cramping is more common with ingested iodine such as that found in shellfish. Diarrhea will not be an immediate side effect, rather experienced hours after the exposure to iodine.
Anaphylaxis
A life-threatening situation, anaphylactic reactions to iodine will present with highly specific symptoms immediately after exposure, or recurrent exposure in someone known to have sensitivity to iodine. If untreated, anaphylactic reactions will lead to death.
Related Articles
References
- University of California San Francisco: Iodine Allergy and Contrast Administration
- Cleveland Clinic: Shellfish Allergies
- MedlinePlus.org: Angioedema
- MedlinePlus.org: Drug Allergies
- American Thyroid Association. Iodine Deficiency. 2020.
- Eastman CJ, Zimmermann MB. The iodine deficiency disorders. In: Feingold KR, Anawalt B, Boyce A, et al., editors. Endotext. South Dartmouth, MA: MDText.com, Inc. Updated February 6, 2018.
- Ahad F, Ganie SA. Iodine, Iodine metabolism and Iodine deficiency disorders revisited. Indian J Endocrinol Metab. 2010;14(1):13-17.
- Kostoglou-athanassiou I, Ntalles K. Hypothyroidism - new aspects of an old disease. Hippokratia. 2010;14(2):82-87.
- American Thyroid Association. Hypothyroidism in Children and Adolescents. 2020.
- National Institutes of Health, Office of Dietary Supplements. Iodine. Updated July 9, 2019.
- U.S. National Library of Medicine. Congenital hypothyroidism. Updated February 11, 2020.
- Johnson LE. Iodine. Merck Manual Professional Version. Updated October 2018.
- Murthy MB, Krishnamurthy B. Severe irritant contact dermatitis induced by povidone iodine solution. Indian J Pharmacol. 2009;41(4):199-200. doi:10.4103/0253-7613.56069
- Puchalski AR, Chopra IJ. Radioiodine treatment of differentiated thyroid cancer despite history of 'iodine allergy'. Endocrinol Diabetes Metab Case Rep. 2014;2014:130084. doi:10.1530/EDM-13-0084
- Schabelman E, Witting M. The relationship of radiocontrast, iodine, and seafood allergies: a medical myth exposed. J Emerg Med. 2010;39(5):701-707. doi:10.1016/j.jemermed.2009.10.014
- National Institutes of Health, Office of Dietary Supplements. Iodine. Updated July 9, 2019.
- American Cancer Society. Radioactive Iodine (Radioiodine) Therapy for Thyroid Cancer. Updated March 14, 2019.
- Centers for Disease Control and Prevention. Potassium iodide (KI). Updated April 4, 2018.
- Kalra S, Unnikrishnan AG, Sahay R. The hypoglycemic side of hypothyroidism. Indian J Endocrinol Metab. 2014;18(1):1-3.doi:+10.4103/2230-8210.126517
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As a bachelor's-prepared registered nurse with more than 15 years of diversified experience, Juliet Wilkinson innerves our health-conscious population through expert articles. She is a motivated professional who believes that preventive care is the first step towards health and well-being.