Skin Disorder & Vitamin D Allergy
If you’re allergic to vitamin D, the allergic reaction can cause a few different skin disorders to flare-up. The most common skin disorders that a vitamin D allergy can cause include hives and eczema, according to Drugs.com. Both allergic skin conditions are extremely itchy and cause inflammation and irritation in the skin. Hives may indicate a severe allergic reaction and needs to be evaluated by a physician. You should only use vitamin D supplements under the direction of a medical doctor.
A vitamin D allergy is considered uncommon. The supplement is commonly used to treat calcium-deficient conditions and is not intended for use in healthy people. The vitamin is found in fish, margarine, oysters, cheese, cream, butter, fortified milk and fortified cereals. If you take too many vitamin D supplements your intestines will absorb too much calcium and this can lead to deposits in the heart and lungs.
- A vitamin D allergy is considered uncommon.
- If you take too many vitamin D supplements your intestines will absorb too much calcium and this can lead to deposits in the heart and lungs.
Allergy to Vitamin B-12
An allergic reaction to vitamin D causes the immune system to develop a defense against the supplement because of a hypersensitivity to the vitamin. The immune system reacts by creating Immunoglobulin E, or IgE antibodies, that attack the vitamin supplement, according to the American Academy of Allergy, Asthma and Immunology. Various other chemicals are released in the body, causing inflammation in the throat, lungs, sinuses and skin. The primary chemical that causes inflammation is histamine, a hormone that helps fight off infection.
- An allergic reaction to vitamin D causes the immune system to develop a defense against the supplement because of a hypersensitivity to the vitamin.
- The immune system reacts by creating Immunoglobulin E, or IgE antibodies, that attack the vitamin supplement, according to the American Academy of Allergy, Asthma and Immunology.
After ingesting a vitamin D supplement, hives can develop within minutes or up to two hours. Hives can occur because of too much histamine released in the skin. The rash appears as welts that appear in clusters anywhere on the body. The rash causes the skin to swell and has defined borders, although the rash can appear in any shape or size, according to MayoClinic.com.
- After ingesting a vitamin D supplement, hives can develop within minutes or up to two hours.
- The rash appears as welts that appear in clusters anywhere on the body.
Signs & Symptoms of Vitamin Allergy
Eczema is a chronic skin disorder where the skin is hypersensitive to various triggers, much like an allergy, according to MedlinePlus. If you experience an allergic reaction to vitamin D and you’re pre-disposed to eczema, the allergic reaction can cause an eczema flare-up. Eczema appears primarily behind the legs, arms and on the face in blisters. The rash can crack, weep and crust-over if scratched.
- Eczema is a chronic skin disorder where the skin is hypersensitive to various triggers, much like an allergy, according to MedlinePlus.
A severe allergic reaction to vitamin D supplements can lead to anaphylaxis, according to Drugs.com. If you develop common anaphylactic shock symptoms, call 911. These symptoms may include chest tightness, shortness of breath, wheezing, facial swelling, hives and dizziness.
Allergy to Vitamin B-12
Signs & Symptoms of Vitamin Allergy
Vitamin K and an Allergy or Rash
Can You Be Allergic to Vitamins?
Does Vitamin B12 Make You Lose Weight?
Too Much Vitamin B12 Side Effects
Supplements That Cause a Skin Rash
What Are Side Effects of Vitamin B12 Tablets?
Vitamin K2 Toxicity
Vitamin D Deficiency & Blurred Vision
- Drugs.com: Vitamin D Medical Information
- Drugs.com: Vitamin D
- American Acadmey of Allergy, Asthma and Immunology: Allergic Reactions
- MayoClinic.com: Hives
- MedlinePlus: Atopic Eczema
- Aranow C. Vitamin D and the immune system. J Investig Med. 2011;59(6):881–886. doi:10.2310/JIM.0b013e31821b8755
- Mirzakhani H, Al-Garawi A, Weiss ST, Litonjua AA. Vitamin D and the development of allergic disease: how important is it?. Clin Exp Allergy. 2015;45(1):114–125. doi:10.1111/cea.12430
- Isolauri E, Huurre A, Salminen S, Impivaara O. The allergy epidemic extends beyond the past few decades. Clin Exp Allergy. 2004;34(7):1007–1010. doi:10.1111/j.1365-2222.2004.01999.x
- Camargo CA Jr, Clark S, Kaplan MS, Lieberman P, Wood RA. Regional differences in EpiPen prescriptions in the United States: the potential role of vitamin D. J Allergy Clin Immunol. 2007;120(1):131–136. doi:10.1016/j.jaci.2007.03.049
- Searing DA, Leung DY. Vitamin D in atopic dermatitis, asthma and allergic diseases. Immunol Allergy Clin North Am. 2010;30(3):397–409. doi:10.1016/j.iac.2010.05.005
- Tian HQ, Cheng L. The role of vitamin D in allergic rhinitis. Asia Pac Allergy. 2017;7(2):65–73. doi:10.5415/apallergy.2017.7.2.65
- Wintermeyer E, Ihle C, Ehnert S, et al. Crucial Role of Vitamin D in the Musculoskeletal System. Nutrients. 2016;8(6):319. Published 2016 Jun 1. doi:10.3390/nu8060319
- Baggerly CA, Cuomo RE, French CB, et al. Sunlight and Vitamin D: Necessary for Public Health. J Am Coll Nutr. 2015;34(4):359–365. doi:10.1080/07315724.2015.1039866
- Schmid A, Walther B. Natural vitamin D content in animal products. Adv Nutr. 2013;4(4):453–462. Published 2013 Jul 1. doi:10.3945/an.113.003780
- Palacios C, Gonzalez L. Is vitamin D deficiency a major global public health problem?. J Steroid Biochem Mol Biol. 2014;144 Pt A:138–145. doi:10.1016/j.jsbmb.2013.11.003
- Stokes CS, Lammert F. Vitamin D supplementation: less controversy, more guidance needed. F1000Res. 2016;5:F1000 Faculty Rev-2017. Published 2016 Aug 17. doi:10.12688/f1000research.8863.1
- Ferraro PM, Taylor EN, Gambaro G, Curhan GC. Vitamin D Intake and the Risk of Incident Kidney Stones. J Urol. 2017;197(2):405–410. doi:10.1016/j.juro.2016.08.084
- Mead MN. Benefits of sunlight: a bright spot for human health [published correction appears in Environ Health Perspect. 2008 May;116(5):A197]. Environ Health Perspect. 2008;116(4):A160–A167. doi:10.1289/ehp.116-a160
- Institute of Medicine. (2010). Food and Nutrition Board. Dietary Reference Intakes for Calcium and Vitamin D. Washington, DC: National Academy Press.
- Litonjua AA, Weiss ST. Is Vitamin D Deficiency to Blame for the Asthma Epidemic? J Allergy Clin Immunol. 2007;120:1031-5.
- Mullins RJ, Camargo CA. Latitude, sunlight, vitamin D, and childhood food allergy/anaphylaxis. Curr Allergy Asthma Rep. 2012 Feb;12(1):64-71.
- National Institutes of Health. Vitamin D: Fact Sheet for Health Professionals.
- Taback SP, Simons FE. Anaphyalxis and Vitamin D: A role for the sunshine hormone? J Allergy Clin Immunol. 2007;120:128-130.
Diane Marks started her writing career in 2010 and has been in health care administration for more than 30 years. She holds a registered nurse license from Citizens General Hospital School of Nursing, a Bachelor of Arts in health care education from California University of Pennsylvania and a Master of Science in health administration from the University of Pittsburgh.