Side Effects of Black Walnut Wormwood Complex
Black walnut and wormwood complex is an herbal remedy used to ease gastrointestinal complaints and expel intestinal parasites. Like most herbal supplements, black walnut and wormwood complex has not been evaluated for human safety by the FDA. Preparations of these herbs can contain inconsistent amounts of the active ingredients, and other contaminants might be present. Contact a doctor if you suspect you are having an adverse reaction to this supplement.
Gastrointestinal Discomfort
The tannins in black walnut can cause nausea and upper abdominal pain, especially if you take it for a long time or you take doses larger than recommended on the product label. Wormwood might also cause nausea, vomiting or abdominal cramps if it is used for a long time. Neither of these herbs should be used by people with liver or kidney problems, or by people with stomach ulcers. Damage to the liver and kidneys is possible if you use them for more than a month, and they can aggravate existing stomach problems.
- The tannins in black walnut can cause nausea and upper abdominal pain, especially if you take it for a long time or you take doses larger than recommended on the product label.
Allergies
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Black walnut might cause allergic reactions in some people, particularly those allergic to other types of nuts. Allergic reactions to black walnut include difficulty breathing, chest pain and hives. Wormwood can cause similar allergic reactions in people who are sensitive to daisies and ragweed.
Pregnant and Lactating Women
If you are pregnant, may be pregnant or are trying to get pregnant, do not take black walnut and wormwood complex for any reason. The effects of these herbs on a developing fetus are not well-documented and could harm the baby. Avoid this complex if you are breastfeeding since it is not well-known if the herbal compound can pass to the baby through your breast milk. Black walnut and wormwood complex should never be given to children under 2 years of age.
- If you are pregnant, may be pregnant or are trying to get pregnant, do not take black walnut and wormwood complex for any reason.
- Avoid this complex if you are breastfeeding since it is not well-known if the herbal compound can pass to the baby through your breast milk.
Wormwood Side Effects
What are the Side Effects of the Wormwood Herb
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Wormwood contains thujone, a powerful convulsant when used in large amounts. Thujone is the ingredient in absinthe believed to have neurotoxic effects with long-term use, including addiction, seizures, hallucinations and possible death from renal or liver failure. People with seizure disorders in particular should avoid using any supplement that contains wormwood.
Interactions With Medications
Both black walnut and wormwood can interfere with other medications and prevent them from entering your bloodstream. Drugs that might become ineffective with this complex include acetaminophen, antacids and proton pump inhibitors. If you use phenobarbital to prevent seizures, wormwood can weaken the drug and make seizures more likely.
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References
- Drugs: Black Walnut
- Rx List: Black Walnut
- Holleran G, Scaldaferri F, Gasbarrini A, Currò D. Herbal medicinal products for inflammatory bowel disease: A focus on those assessed in double-blind randomised controlled trials. Phytother Res. 2020;34(1):77-93. doi:10.1002/ptr.6517
- Omer B, Krebs S, Omer LM, Noor TO. Immune modulation by wormwood (Artemisia absinthium) – results of a double blind, placebo controlled trial on Crohn's disease patients. Planta Med 2007;73-P_007. doi:10.1055/s-2007-986789
- Krebs S, Omer TN, Omer B. Wormwood (Artemisia absinthium) suppresses tumour necrosis factor alpha and accelerates healing in patients with Crohn's disease - A controlled clinical trial. Phytomedicine. 2010;17(5):305-9. doi:10.1016/j.phymed.2009.10.013
- Beshay EVN. Therapeutic efficacy of Artemisia absinthium against Hymenolepis nana: in vitro and in vivo studies in comparison with the anthelmintic praziquantel. J Helminthol. 2018;92(3):298-308. doi:10.1017/s0022149x17000529
- Elfawal MA, Towler MJ, Reich NG, Golenbock D, Weathers PJ, Rich SM. Dried whole plant Artemisia annua as an antimalarial therapy. PLoS One. 2012;7(12):e52746. doi:10.1371/journal.pone.0052746
- Weathers PJ, Towler M, Hassanali A, Lutgen P, Engeu PO. Dried-leaf Artemisia annua: A practical malaria therapeutic for developing countries? World J Pharmacol. 2014;3(4):39-55. doi:10.5497/wjp.v3.i4.39
- Almario CV, Ballal ML, Chey WD, Nordstrom C, Khanna D, Spiegel BMR. Burden of gastrointestinal symptoms in the United States: Results of a nationally representative survey of over 71,000 Americans. Am J Gastroenterol. 2018;113(11):1701-1710. doi:10.1038/s41395-018-0256-8
- Mcmullen MK, Whitehouse JM, Whitton PA, Towell A. Bitter tastants alter gastric-phase postprandial haemodynamics. J Ethnopharmacol. 2014;154(3):719-27. doi:10.1016/j.jep.2014.04.041
- Mcmullen MK, Whitehouse JM, Towell A. Bitters: Time for a New Paradigm. Evid Based Complement Alternat Med. 2015;2015:670504.
- Stebbings S, Beattie E, Mcnamara D, Hunt S. A pilot randomized, placebo-controlled clinical trial to investigate the efficacy and safety of an extract of Artemisia annua administered over 12 weeks, for managing pain, stiffness, and functional limitation associated with osteoarthritis of the hip and knee. Clin Rheumatol. 2016;35(7):1829-36. doi:10.1007/s10067-015-3110-z
- Forouzanfar F, Hosseinzadeh H. Medicinal herbs in the treatment of neuropathic pain: a review. Iran J Basic Med Sci. 2018;21(4):347-358. doi:10.22038%2FIJBMS.2018.24026.6021
- Yang M, Guo MY, Luo Y, et al. Effect of Artemisia annua extract on treating active rheumatoid arthritis: A randomized controlled trial. Chin J Integr Med. 2017;23(7):496-503. doi:10.1007/s11655-016-2650-7
- Basiri Z, Zeraati F, Esna-ashari F, et al. Topical Effects of Artemisia Absinthium Ointment and Liniment in Comparison with Piroxicam Gel in Patients with Knee Joint Osteoarthritis: A Randomized Double-Blind Controlled Trial. Iran J Med Sci. 2017;42(6):524-531.
- Hijazi AM, Salhab AS. Effects of Artemisia monosperma ethanolic leaves extract on implantation, mid-term abortion and parturition of pregnant rats. J Ethnopharmacol. 2010;128(2):446-51. doi:10.1016/j.jep.2010.01.030
- Lachenmeier DW. Wormwood (Artemisia absinthium L.)--a curious plant with both neurotoxic and neuroprotective properties?. J Ethnopharmacol. 2010;131(1):224-7. doi:10.1016/j.jep.2010.05.062
- Açıkgöz SK, Açıkgöz E. Gastrointestinal bleeding secondary to interaction of Artemisia absinthium with warfarin. Drug Metabol Drug Interact. 2013;28(3):187-9. doi:10.1515/dmdi-2013-0021
- Brown AC. Kidney toxicity related to herbs and dietary supplements: Online table of case reports. Part 3 of 5 series. Food Chem Toxicol. 2017;107(Pt A):502-519. doi:10.1016/j.fct.2016.07.024
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