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- Cancer Research: Dietary Curcumin Inhibits Chemotherapy-induced Apoptosis in Models of Human Breast Cancer
- Cancer Research: Dietary Curcumin Inhibits Chemotherapy-induced Apoptosis in Models of Human Breast Cancer
- American Journal of Clinical Nutrition: Effect of Cinnamon and Turmeric on Urinary Oxalate Excretion
- American Journal of Clinical Nutrition: Effect of Cinnamon and Turmeric on Urinary Oxalate Excretion
- Pol Merkur Lekarski: Hidden Food Allergens
- Pol Merkur Lekarski: Hidden Food Allergens
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Many people flavor traditional and exotic meals like lentil soup and vegetable biryani with curry powder. The spice contains curcumin, the ingredient that gives turmeric its yellow color, which is an antioxidant and anti-inflammatory. However, some people should think twice before dousing dishes in curry powder or ingesting supplements. Increased amounts of the spice may bring harmful side effects for individuals troubled by various illnesses like breast cancer and heart disease.
If you are experiencing serious medical symptoms, seek emergency treatment immediately.
Increased Bleeding
Turmeric is a natural blood thinner and can increase bleeding if combined with certain medicines. It should not be used with anticoagulants (prevents blood clotting) or antiplatelet drugs like heparin, warfarin or clopidogrel. Check with a dietitian or nutritionist for tasty alternatives to curry if you are taking any of these types of medication.
May Suppress Chemo Medications
Side Effects of the Curcumin in Turmeric
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Chemotherapy patients should also be wary of indulging in too much curry. Curcumin might hinder cyclophosphamide, an immunosuppressive agent used in treating breast cancer survivors, according to a 2002 study conducted by researchers from The Lineberger Comprehensive Cancer Center of The University of North Carolina at Chapel Hill. Consult a doctor before eating turmeric and curry-laden dishes if you are undergoing treatment.
Kidney Stones
Additional doses of turmeric may result in renal problems for predisposed people. In a 2008 study done by University of Wyoming Department of Family and Consumer Sciences investigators found that turmeric increased urinary oxalate levels, which raised the risk of kidney stone formation in those prone to the condition.
The Piperine Factor
How to Use Turmeric to Reduce Inflammation and Pain
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Curcumin supplements may boost benefits for some people but carry a hidden danger for those suffering from seizures and heart diseases. In her book, "An Evidence-Based Approach to Dietary Phytochemicals," nutritionist Jane Higdon notes that some pills contain piperine, an additive that impedes the metabolism of curcumin 1. However, it can delay the elimination of drugs like phenytoin (Dilantin), propranolol (Inderal), and theophylline for prescribed patients.
Trouble for Celiacs
Some sauces and spice mixes, like curries, contain gluten, a protein in rye, wheat and barley that may prompt an allergic reaction like diarrhea or stomach cramping from those diagnosed with celiac disease. A 2004 study done by researchers from the Instytutu Matki i Dziecka of Klinika Pediatrii in Poland identified curry powder as one of many food products containing undisclosed gluten. Check product labels for ingredients, and shop for gluten-free alternatives to curry sauces and powder mixes.
May Aggravate Gastrointestinal Disorders
Though, research is inconclusive, some doctors are steering patients with abdominal issues away from turmeric supplements and urging caution with curry. In their 2003 book, “Herb-Drug Interactions in Oncology,” Barrie R. Cassileth and Charles D. Lucarelli warn those afflicted with gastrointestinal illnesses like stomach ulcers, bile duct obstruction and gallstones should not take the spice as a supplement 4. Consult a physician before consuming pills or products containing curry powder or turmeric if susceptible to these medical conditions.
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References
- "An Evidence-Based Approach to Dietary Phytochemicals"; Jane Higdon; 2007
- Cancer Research: Dietary Curcumin Inhibits Chemotherapy-induced Apoptosis in Models of Human Breast Cancer
- American Journal of Clinical Nutrition: Effect of Cinnamon and Turmeric on Urinary Oxalate Excretion
- "Herb-Drug Interactions in Oncology"; Barrie R. Cassileth, Charles D. Lucarelli; 2003
- Pol Merkur Lekarski: Hidden Food Allergens
- National Center for Complementary and Integrative Health (NCCIH). Turmeric. Updated November 27, 2018.
- Gupta SC, Patchva S, Aggarwal BB. Therapeutic roles of curcumin: lessons learned from clinical trials. AAPS J. 2013;15(1):195-218. doi:10.1208/s12248-012-9432-8
- Daily JW, Yang M, Park S. Efficacy of turmeric extracts and curcumin for alleviating the symptoms of joint arthritis: a systematic review and meta-analysis of randomized clinical trials. J Med Food. 2016;19(8):717-29. doi:10.1089/jmf.2016.3705
- Hewlings SJ, Kalman DS. Curcumin: A review of its effects on human health. Foods. 2017;6(10). doi:10.3390/foods6100092
- Cavaleri F. Presenting a new standard drug model for turmeric and its prized extract, curcumin. Int J Inflam. 2018;2018:5023429.
- Khayat S, Fanaei H, Kheirkhah M, Moghadam ZB, Kasaeian A, Javadimehr M. Curcumin attenuates severity of premenstrual syndrome symptoms: a randomized, double-blind, placebo-controlled trial. Complement Ther Med. 2015;23(3):318-24. doi:10.1016/j.ctim.2015.04.001
- Maulina T, Diana H, Cahyanto A, Amaliya A. The efficacy of curcumin in managing acute inflammation pain on the post-surgical removal of impacted third molars patients: a randomised controlled trial. J Oral Rehabil. 2018;45(9):677-683. doi:10.1111/joor.12679
- Buhrmann C, Mobasheri A, Busch F, et al. Curcumin modulates nuclear factor kappaB (NF-kappaB)-mediated inflammation in human tenocytes in vitro: role of the phosphatidylinositol 3-kinase/Akt pathway. J Biol Chem. 2011;286(32):28556-66. doi:10.1074/jbc.M111.256180
- Fusar-poli L, Vozza L, Gabbiadini A, et al. Curcumin for depression: a meta-analysis. Crit Rev Food Sci Nutr. 2019;1-11. doi:10.1080/10408398.2019.1653260
- Kunnumakkara AB, Bordoloi D, Padmavathi G, et al. Curcumin, the golden nutraceutical: multitargeting for multiple chronic diseases. Br J Pharmacol. 2017;174(11):1325-1348. doi:10.1111/bph.13621
- Burge K, Gunasekaran A, Eckert J, Chaaban H. Curcumin and intestinal inflammatory diseases: molecular mechanisms of protection. Int J Mol Sci. 2019;20(8). doi:10.3390/ijms20081912
- Bai X, Oberley-deegan RE, Bai A, et al. Curcumin enhances human macrophage control of Mycobacterium tuberculosis infection. Respirology. 2016;21(5):951-7. doi:10.1111/resp.12762
- Lee SW, Nah SS, Byon JS, et al. Transient complete atrioventricular block associated with curcumin intake. Int J Cardiol. 2011;150(2):e50-2. doi:10.1016/j.ijcard.2009.09.530
- Milton S. Hershey Medical Center. Possible interactions with: turmeric. Updated January 5, 2015.
- American Academy of Allergy, Asthma & Immunology. Can spices cause allergic reactions?
- Tayyem RF, Heath DD, Al-delaimy WK, Rock CL. Curcumin content of turmeric and curry powders. Nutr Cancer. 2006;55(2):126-31. doi:10.1207/s15327914nc5502_2
- Gupta SC, Kismali G, Aggarwal BB. Curcumin, a component of turmeric: from farm to pharmacy. Biofactors. 2013 Jan-Feb;39(1):2-13. DOI: 10.1002/biof.1079.
- Gupta SC, Patchva S, Koh W, Aggarwal BB. Discovery of curcumin, a component of golden spice, and its miraculous biological activities. Clin Exp Pharmacol Physiol. 2012 Mar;39(3):283-99. DOI: 10.1111/j.1440-1681.2011.05648.x.
- Patrick K, Stanbrook MB. Take turmeric with a grain of salt. CMAJ. 2018;190(43):E1270. doi:10.1503/cmaj.181358
Writer Bio
Natasha Allen is a New York-based freelance writer and publishing veteran with more than 10 years of experience. She has written and worked with media outlets like Womanrock.com, Global Black Woman, Essence Communications and Penguin Putnam Inc. Allen is a graduate of Columbia University Graduate School of Journalism.