Pantoprazole Side Effects

Pantoprazole is a medication used to treat esophageal damage from acid-related diseases such as acid reflux and Zollinger-Ellison syndrome (a condition of ulcers in the stomach and small intestine) 2. Pantoprazole is a proton pump inhibitor that reduces the amount of stomach acid produced 2. This medication is available as an enteric-coated tablet and through intravenous (through your vein) injection. Typically, you will receive 20 to 40 milligrams of pantoprazole daily 23.

Common Side Effects

Avoid chronic pantoprazole use 2. This medication may prevent your body from absorbing vitamin B12 from your consumed foods. Symptoms of vitamin B12 deficiency include:

  • weakness
  • paleness
  • fatigue
  • trouble breathing
  • tachycardia (fast heartbeat)
  • reports 1

Harmful Side Effects

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It can also cause an increased cough, a urinary tract infection and a rash. In the same study, these symptoms occurred in greater than 1 percent of the 836 patients studied. Call your doctor when these side effects appear.

Rare Side Effects

Pantoprazole can also cause irregular heart rhythms, low or high blood pressure, hemorrhage (bleeding), syncope (fainting) and a fast heart rate (tachycardia) 2. Pantoprazole can also irritate your digestive system and cause esophageal bleeding, gastrointestinal carcinoma (stomach or intestinal cancer), rectal hemorrhage and ulcerative colitis (a form of inflammatory bowel disease) 2.

Additional Concerns

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Pantoprazole can contaminate your breast milk and harm your child 2. Notify your doctor if you are breastfeeding, and she will find a better anti-acid medication to treat your symptoms.

Tell your doctor if you are taking ampicillin, warfarin, clopidogrel, iron or ketoconazole. Pantoprazole can combine with these medications and lead to the aforementioned side effects 2.

  • Pantoprazole can contaminate your breast milk and harm your child 2.