Is it OK to Take a B-Complex Vitamin Along With a Multivitamin Daily?
Taking daily vitamins is a healthy habit to form; however, taking more than you need could lead to trouble. If you take high doses of some B vitamins, you could face serious side effects, including increased risk of heart disease, stroke, stomach ulcers and liver damage. Ask your doctor if you need to take a multivitamin, a vitamin B complex supplement or both.
To find out if you can safely combine multivitamins and vitamin B complex supplements, add the totals of the doses of vitamin B in both supplements. Here are the recommended daily allowances, or RDA, for the B vitamins most commonly used in B complex formulas: vitamin B-1, 1.1 mg to 1.5 mg; vitamin B-2, 1.1 mg to 1.6 mg; vitamin B-3, 14 mg to 17 mg; vitamin B-5, 5 mg to 7 mg; vitamin B-6, 1.3 mg to 2.0 mg; vitamin B-12, 2.4 mg to 2.8 mg. In general, men need more vitamin B than women, but pregnant and breastfeeding women as well as older adults also might need higher amounts.
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Taking a multivitamin plus vitamin B complex that increases your intake of vitamin B beyond the RDA might prove prudent, but ask your doctor first. Reasons to take extra vitamin B-1 include thiamine deficiency, prevention of cataracts and to alleviate symptoms of alcohol withdrawal. Doctors might prescribe niacin, or vitamin B-3, in amounts up to 4 g a day to treat high cholesterol or prevent heart disease in people with high cholesterol. Other reasons to take niacin include slowing the progression of Alzheimer's disease and delaying the progression of Type 1 diabetes. You can take up to 10 mg of vitamin B-5 daily as a supplement. Vitamin B-6 in doses higher than the RDA can treat B-6 deficiency, premenstrual syndrome, kidney disease and prevent a vision problem called macular degeneration.
- Taking a multivitamin plus vitamin B complex that increases your intake of vitamin B beyond the RDA might prove prudent, but ask your doctor first.
- Doctors might prescribe niacin, or vitamin B-3, in amounts up to 4 g a day to treat high cholesterol or prevent heart disease in people with high cholesterol.
Popular reasons for taking vitamin B complex supplements with or without multivitamins include efforts to increase athletic performance, improve mood, pass drug screening tests and improve orgasm. The long list of other possible uses for vitamin B complex includes treating AIDS, attention-deficit hyperactivity disorder, alcoholism and acne. Evidence for such uses ranges from insufficient to nonexistent. Don’t take vitamin B based on anecdotes from friends or rumors on the Internet. Taking too much vitamin B can prove toxic.
- Popular reasons for taking vitamin B complex supplements with or without multivitamins include efforts to increase athletic performance, improve mood, pass drug screening tests and improve orgasm.
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Don’t take vitamin B complex supplements and multivitamins without consulting a medical professional and don’t exceed dose recommendations unless a doctor specifically recommends that you do so. Long-term use of some B vitamins can cause vision loss and nerve damage and worsen kidney and liver disease. Short-term use of some B vitamins in high doses also can put your health in jeopardy. In 2005, for instance, more than 3,000 people in the United States who took niacin in high doses contacted poison control centers with symptoms of serious overdose.
- Don’t take vitamin B complex supplements and multivitamins without consulting a medical professional and don’t exceed dose recommendations unless a doctor specifically recommends that you do so.
- Short-term use of some B vitamins in high doses also can put your health in jeopardy.
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- University of Maryland Medical Center: Vitamin B3 (Niacin)
- Medline Plus: Niacin and Niacinamide (Vitamin B3)
- Centers for Disease Control and Prevention: Use of Niacin in Attempts to Defeat Urine Drug Testing -- Five States, January to September 2006
- Medline Plus: Thiamine (Vitamin B1)
- Medline Plus: Riboflavin (Vitamin B2)
- Medline Plus: Pantothenic Acid (Vitamin B5)
- Holick MF, Gordon CM. Patient Guide to Vitamin D Deficiency. The Journal of Clinical Endocrinology & Metabolism. 2011;96(7):1-2. doi:10.1210/jcem.96.7.zeg33a
- Sunyecz JA. The use of calcium and vitamin D in the management of osteoporosis. Ther Clin Risk Manag. 2008;4(4):827-836. doi:10.2147/tcrm.s3552
- Giovannucci E, Liu Y, Hollis BW, Rimm EB. 25-hydroxyvitamin D and risk of myocardial infarction in men: a prospective study. Arch Intern Med. 2008;168(11):1174-1180. doi:10.1001/archinte.168.11.1174
- Gorham ED, Garland CF, Garland FC, et al. Optimal vitamin D status for colorectal cancer prevention: a quantitative meta analysis. Am J Prev Med. 2007;32(3):210-216. doi:10.1016/j.amepre.2006.11.004
- Lappe JM, Travers-Gustafson D, Davies KM, Recker RR, Heaney RP. Vitamin D and calcium supplementation reduces cancer risk: results of a randomized trial. The American Journal of Clinical Nutrition. 2007;85(6):1586-1591. doi:10.1093/ajcn/85.6.1586
- Prentice RL, Pettinger MB, Jackson RD, et al. Health risks and benefits from calcium and vitamin D supplementation: Women’s Health Initiative clinical trial and cohort study. Osteoporos Int. 2013;24(2):567-580. doi:10.1007/s00198-012-2224-2
- Urashima M, Segawa T, Okazaki M, Kurihara M, Wada Y, Ida H. Randomized trial of vitamin D supplementation to prevent seasonal influenza A in schoolchildren. Am J Clin Nutr. 2010;91(5):1255-1260. doi:10.3945/ajcn.2009.29094
- Salehpour A, Hosseinpanah F, Shidfar F, et al. A 12-week double-blind randomized clinical trial of vitamin D₃ supplementation on body fat mass in healthy overweight and obese women. Nutr J. 2012;11:78. doi:10.1186/1475-2891-11-78
- Carrillo AE, Flynn MG, Pinkston C, et al. Impact of vitamin D supplementation during a resistance training intervention on body composition, muscle function, and glucose tolerance in overweight and obese adults. Clin Nutr. 2013;32(3):375-381. doi:10.1016/j.clnu.2012.08.014
- Marcinowska-Suchowierska E, Kupisz-Urbańska M, Łukaszkiewicz J, Płudowski P, Jones G. Vitamin D Toxicity-A Clinical Perspective. Front Endocrinol. 2018;9:550. doi:10.3389/fendo.2018.00550
- Ross AC, Manson JE, Abrams SA, et al. The 2011 report on dietary reference intakes for calcium and vitamin D from the Institute of Medicine: what clinicians need to know. J Clin Endocrinol Metab. 2011;96(1):53-58. doi:10.1210/jc.2010-2704
- Bouillon R, Van Schoor NM, Gielen E, et al. Optimal vitamin D status: a critical analysis on the basis of evidence-based medicine. J Clin Endocrinol Metab. 2013;98(8):E1283-E1304. doi:10.1210/jc.2013-1195
- American Academy of Dermatology. Position Statement of Vitamin D. 2010.
- Taksler GB, Cutler DM, Giovannucci E, Keating NL. Vitamin D deficiency in minority populations. Public Health Nutr. 2015;18(3):379-391. doi:10.1017/S1368980014000457
- Holick MF, Binkley NC, Bischoff-Ferrari HA, et al. Evaluation, treatment, and prevention of vitamin D deficiency: an Endocrine Society clinical practice guideline. J Clin Endocrinol Metab. 2011;96(7):1911-1930. doi:10.1210/jc.2011-0385
- Cannell JJ, Vieth R, Umhau JC, et al. Epidemic Influenza and Vitamin D. Epidemiol Infect. 2006; 134:1129-40.
- Carrillo AE1, Flynn MG, Pinkston C, Markofski MM, Jiang Y, Donkin SS, Teegarden D. Impact of Vitamin D Supplementation During a Resistance Training Intervention on Body Composition, Muscle Function, and Glucose Tolerance in Overweight and Obese Adults. Clin Nutr. 2013 Jun;32(3):375-81. doi: 10.1016/j.clnu.2012.08.014. Epub 2012 Aug 31.
- Ginde AA, Mansbach JM, Camargo CA, Jr. Association Between Serum 25-Hydroxyvitamin D Level and Upper Respiratory Tract Infection in the Third National Health and Nutrition Examination Survey. Arch Intern Med. 2009; 169:384-90.
- Giovannucci E, Liu Y, Hollis BW, Rimm EB. 25-hydroxyvitamin D and Risk of Myocardial Infarction in Men: a Prospective Study. Arch Intern Med. 2008; 168:1174-80.
- Gorham ED, Garland CF, Garland FC, Grant WB, Mohr SB, Lipkin M, Newmark HL, Giovannucci E, Wei M, Holick MF. Optimal Vitamin D Status for Colorectal Cancer Prevention: a Quantitative Meta-analysis. Am J Prev Med. 2007 Mar;32(3):210-6.
- Heaney, Robert P. “The Vitamin D Requirement in Health and Disease.” The Journal of Steroid Biochemistry & Molecular Biology 97 (2005):13-9.
- Holick MF. Vitamin D. In: Shils M, Olson J, Shike M, Ross AC, ed. Modern Nutrition in Health and Disease, 9th ed. Baltimore: Williams and Wilkins, 1999.
- National Institutes of Health Office of Dietary Supplements. Vitamin D: Dietary Supplement Fact Sheet. University of Ottawa Evidence-based Practice Center. Effectiveness and Safety of Vitamin D in Relation to Bone Health. Agency for Healthcare Research and Quality. Aug 2007: 07-E013.
- Salehpour A1, Hosseinpanah F, Shidfar F, Vafa M, Razaghi M, Dehghani S, Hoshiarrad A, Gohari M. A 12-week Double-blind Randomized Clinical Trial of Vitamin D₃ Supplementation on Body Fat Mass in Healthy Overweight and Obese Women. Nutr J. 2012 Sep 22;11:78. doi: 10.1186/1475-2891-11-78.
- Urashima M, Segawa T, Okazaki M, Kurihara M, Wada Y, Ida H. Randomized Trial of Vitamin D Supplementation to Prevent Seasonal Influenza A in Schoolchildren. Am J Clin Nutr. 2010 91:1255-60. Epub 2010 Mar 10.
- Wilkins, Consuelo H. and Yvette I. Sheline, et al. “Vitamin D Deficiency Is Associated with Low Mood and Worse Cognitive Performance in Older Adults.” American Journal of Geriatric Psychiatry 14 (2006): 1032-40.
Kathryn Gilhuly is a wellness coach based in San Diego. She helps doctors, nurses and other professionals implement lifestyle changes that focus on a healthy diet and exercise. Gilhuly holds a Master of Science in health, nutrition and exercise from North Dakota State University.