Prostate specific antigen or PSA is a specific antigen produced by the prostate. Levels of this antigen are measured to determine the presence of disease. PSA can determine the presence of prostate cancer, benign prostatic hypertrophy and prostatitis. PSA is measured in nanograms; normal levels of the antigen are 4 nanograms per milliliter and below. There are several medications and herbs that can affect PSA levels.
Certain herbs have been known to cause lower PSA levels in men. Saw palmetto is often used to treat the symptoms of BPH. In comparison to pharmaceutical treatments, saw palmetto is often less expensive and better tolerated. Another supplement that has been used for the treatment of prostate conditions is PC-SPES. This is a mixture of several Chinese herbs consisting of ganoderma, rabdosia, isatis, scutellaria, chrysanthemum, glycrrhiza, panax pseudoginseng and saw palmetto. While herbals treatments are sometimes used in individuals as part of a medical treatment plan, they can impair the ability to obtain accurate test results. Use of any herbal supplement should be discussed with a health care profession prior to beginning a regimen.
- Certain herbs have been known to cause lower PSA levels in men.
- Saw palmetto is often used to treat the symptoms of BPH.
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According to Renal and Urology News, common medications such as statins and NSAIDS, or non-steroidal anti inflammatory drugs, can produce lower PSA levels during testing 1. NSAIDs are commonly used for the treatment of mild to moderate pain, arthritis and headache. Aspirin is a widely consumed NSAID that is used to prevent stroke and heart attack. Other NSAIDs include ibuprofen, Celebrex, and toradol. Statins are drugs that are prescribed to lower elevated cholesterol levels. They work by reducing the amount of cholesterol production in the liver. Usage of these medications can make accurate detection of PSA levels in the body difficult because they can lower PSA levels. Physicians may not be about to correctly determine the amount of antigen that is being produced by the prostate, allowing for increased instance of misdiagnosis.
- According to Renal and Urology News, common medications such as statins and NSAIDS, or non-steroidal anti inflammatory drugs, can produce lower PSA levels during testing 1.
- Usage of these medications can make accurate detection of PSA levels in the body difficult because they can lower PSA levels.
According to studies conducted with the participation of the National Cancer Institute vitamin D has bee shown to reduce levels of PSA in men 2. The mechanism behind the success of vitamin D in the reduction of PSA levels in still not completely known and is currently being researched. Vitamin D can be obtained from natural sources such as fish, mushrooms, eggs and dairy products, or in dietary supplements. As with any new health course of therapy, it should be discussed with your health care provider.
- According to studies conducted with the participation of the National Cancer Institute vitamin D has bee shown to reduce levels of PSA in men 2.
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- Renal and Urology News
- National Cancer Institute
- Academy of American Family Physician
- Hamilton RJ, Goldberg KC, Platz EA, et al. The influence of statin medications on prostate-specific antigen levels. J Natl Cancer Inst 2008;100:1511-1518.
- Hamilton RJ, Platz EA, Goldberg KC, Freedland SJ. The association between cholesterol and PSA. J Urol 2008; 179: 721 abstract 2094.
- YuPeng L, YuXue Z, PengFei L, eta l. Cholesterol levels in blood and the risk of prostate cancer: a meta-analysis of 14 prospective studies. Cancer Epidemiol Biomarkers Prev 2015; 24: 1086-1093.
- Zapata D, Howard LE, Allott EH et al. Is PSA related to serum cholesterol and does the relationship differ between black and white men? Prostate 2015; 75: 1877-1885.
Nicole Stewart is a freelance writer and nurse. She has a diverse background in the fields of health care and business. Her health care experience includes pediatrics, geriatrics, and mental health. Her business experience includes extensive knowledge of the health insurance, marketing and public relations.