The pneumonia shot is a vaccination given to prevent illness caused by Streptococcus pneumoniae bacteria, also known as pneumococcus. Infection with this bacteria can cause serious problems, including pneumonia, blood infection or meningitis -- infection of the coverings surrounding the brain and spinal cord.
If you are experiencing serious medical symptoms, seek emergency treatment immediately.
Two forms of pneumococcal vaccines, PCV13 (Prevnar 13) and PPSV23 (Pneumovax 23), are available and used in specific circumstances. The Centers for Disease Control and Prevention (CDC) recommends pneumococcal vaccination for all children younger than 2 years of age, all adults 65 years and older and people between these ages who smoke or have certain medical conditions 56. Although generally very safe, pneumonia shots may produce side effects, which are usually mild and transient.
Injection Site Symptoms
At least half of all people who receive pneumonia shots will experience mild side effects in the area of injection, such as pain or redness. Less commonly, swelling or hardness may also occur in the area. These symptoms can limit movement of the arm or leg where the shot was given.
Injection site side effects may be more common when people receive repeat injections. These side effects should diminish within a couple days of receiving the shot. Acetaminophen (Tylenol) or a nonsteroidal anti-inflammatory drug (NSAID) like ibuprofen (Advil, Motrin) or naproxen (Aleve) may help relieve the pain or soreness. A cold compress may be effective in reducing injection site swelling.
- At least half of all people who receive pneumonia shots will experience mild side effects in the area of injection, such as pain or redness.
- These symptoms can limit movement of the arm or leg where the shot was given.
Generalized Side Effects
Flu-Like Symptoms After a Flu Shot
Fever, fatigue, sleepiness, fussiness, irritability, decreased appetite and nausea may occur after pneumococcal shots. These symptoms are generally mild. But about 1 in 20 children receiving PCV13 develop a fever over 102 degrees Fahrenheit, according to CDC.
Joint or muscle pain and headaches may also occur. Generalized effects may be more common in children than in adults.
When present, generalized effects occur within the first few days following vaccination. Acetaminophen or an NSAID may help relieve headaches, other pain or a fever. Massage or a warm bath or shower may help alleviate muscle pain.
- Fever, fatigue, sleepiness, fussiness, irritability, decreased appetite and nausea may occur after pneumococcal shots.
As with any vaccination, pneumonia shots may rarely cause a severe allergic reaction. Symptoms of these reactions typically include generalized hives, swelling, shortness of breath, wheezing, lightheadedness, dizziness or loss of consciousness. The symptoms occur in the first few minutes or hours after a pneumonia shot.
Fortunately, severe allergic reactions are very rare after any type of vaccination, including pneumonia shots. CDC estimates that they occur in about 1 out of every 1 million vaccinations.
- As with any vaccination, pneumonia shots may rarely cause a severe allergic reaction.
- Fortunately, severe allergic reactions are very rare after any type of vaccination, including pneumonia shots.
Warnings and Precautions
Side Effects of the Tetanus Shot
If you are allergic to a vaccine against diphtheria -- a bacteria that can cause severe throat infections -- you should not receive PCV13 4. This is because PCV13 contains a protein from the diphtheria bacteria, so you could be allergic to PCV13 as well 4. Diphtheria-containing vaccines include DTaP, DT, Td and Tdap 4. The safety of pneumonia shots during pregnancy has not been proven. If you are or think you may be pregnant, tell your healthcare provider before receiving a pneumococcal vaccination.
See your doctor if you develop a high fever after a pneumonia shot or if you have any generalized symptoms that persist more than a few days.
This may indicate that you actually have another illness unrelated to your recent vaccination. Seek immediate medical attention if you have any symptoms of a severe allergic reaction.
Reviewed and revised by: Mary D. Daley, M.D.
- If you are allergic to a vaccine against diphtheria -- a bacteria that can cause severe throat infections -- you should not receive PCV13 4.
- See your doctor if you develop a high fever after a pneumonia shot or if you have any generalized symptoms that persist more than a few days.
Flu-Like Symptoms After a Flu Shot
Side Effects of the Tetanus Shot
Pros and Cons About the HPV Vaccine
Flu Symptoms After a Tetanus Injection
Side Effects of a Meningitis Vaccine
Flu Shot Side Effects, Including Fatigue
Signs & Symptoms of Type A Influenza
What Happens If Varicella Vaccine Is Administered Intramuscularly?
Flu Shot Disadvantages
Symptoms & Effects of Malaria
- American Family Physician: Pneumococcal Conjugate Vaccine: What a Parent Needs to Know
- Daily Med: Pneumovax 23 -- Pneumococcal Vaccine Polyvalent Injection, Solution
- Daily Med: Prevnar 13 -- Pneumococcal 13-Valent Conjugate Vaccine Injection, Suspension
- Vaccines.gov: Diphtheria
- Centers for Disease Control and Prevention: Pneumococcal Vaccination: What Everyone Should Know
- Centers for Disease Control and Prevention: Possible Side-Effects From Vaccines
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- Von elten KA, Duran LL, Banks TA, Banks TA, Collins LC, Collins LC. Systemic inflammatory reaction after pneumococcal vaccine: a case series. Hum Vaccin Immunother. 2014;10(6):1767-70. doi:10.4161/hv.28559
- American Lung Association. "Trends in Pneumonia and Influenza: Morbidity and Mortality." Washington, D.C.; issued November 2015.
- Daniels, C.; Rodgers, P.; and Shelton, C. "A Review of Pneumococcal Vaccines: Current Polysaccharide Vaccine Recommendations and Future Protein Antigens." J Pediatr Pharmacol Ther. 2016; 21(1):27-35. doi:10.5863/1551-6776-21.1.27
- Tagaro, A.; Bote, E.; Sanchez, A. et al. "Complications of Pneumococcal Bacteremia After Thirteen-valent Conjugate Vaccine Withdrawal." Ped Infect Dis J. 2016: 35(12):1281-7. doi:10.1097/INF.0000000000001302
- CDC. "FastStats: Pneumonia." Updated January 20, 2017.
- Centers for Disease Control and Prevention (CDC). "Pneumococcal Vaccine Recommendations." Atlanta, Georgia; updated December 6, 2017.
Laura Candelaria is a family nurse practitioner and assistant professor of nursing and nutritional science. Her experience includes neonatal and pediatric intensive-care, women's oncology, gynecology, obstetrics, lactation, nutrition and infertility. She has been published in "Nursing Spectrum," "Newsday" and on various websites.