Dehydration & Potassium Levels
Dehydration occurs when the body lacks enough water to continue its metabolic processes. Water is an essential compound for the body’s many biochemical reactions. It is used during energy production and excretion of toxic materials. When the body cannot keep up with its fluid needs, dehydration ensues. Dehydration can then affect many cellular processes in the body. One effect of dehydration is on the potassium level in the blood.
The Facts
Potassium is an important electrolyte in your body. Electrolytes are electrically charged molecules important for fluid balance and waste removal. Potassium is also important in maintaining a regular heart rhythm. Most potassium exists inside the body’s cells, so changes in the level of potassium in the blood stream can cause serious health effects.
- Potassium is an important electrolyte in your body.
Symptoms of Dehydration
What Is the Most Abundant Electrolyte Found in Blood Plasma?
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Initial symptoms of dehydration include dry lips and mouth, dry skin, increased heart rate and decreased urine output. If the dehydration worsens, the heart rate increases more and blood pressure can fall, resulting in light-headedness, dizziness and loss of consciousness. In severe dehydration, shock and brain, liver and kidney damage can result.
Considerations
There are many causes of dehydration, but essentially a person becomes dehydrated if they lose too much fluid or become unable to ingest enough water. The elderly can become dehydrated because they can’t recognize how much fluid they are losing, according to the Merck Manuals. Infants become dehydrated because the amount of fluid they lose represents a larger proportion of their bodily fluids when compared to that of older children and adult experiencing dehydration. In the most common form of dehydration, electrolytes such as potassium are lost, resulting in decreased levels in the blood stream.
- There are many causes of dehydration, but essentially a person becomes dehydrated if they lose too much fluid or become unable to ingest enough water.
Causes
Symptom of Confusion and Electrolyte Imbalance
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Common causes of dehydration include excessive sweating, vomiting and diarrhea. All these can result in hypokalemia, or low potassium levels. Diabetic ketoacidosis, in which a person with diabetes cannot use sugar as energy source and resorts to the use of fats to satisfy its energy requirements, can also result in low potassium levels, or can cause hyperkalemia, abnormally high level of potassium.
Effects
Hypokalemia can result in muscle weakness and cramps, and even paralysis. According to the Merck Manuals, since potassium is important for preserving a normal heart rhythm, hypokalemia and hyperkalemia can both cause abnormalities called arrhythmias. In particular, a high potassium level can result in a life-threatening arrhythmia called ventricular fibrillation, which impairs the heart’s ability to pump blood to the tissues.
Related Articles
References
- Lab Tests Online: Potassium
- Dylewski JF, Linas S. Variability of potassium blood testing: Imprecise nature of blood testing or normal physiologic changes? Mayo Clinic Proceedings. 2018. 93(5):551-554. doi:10.1016/j.mayocp.2018.03.019
- Friedman PA, Scott CG, Bailey K, et al. Errors of classification with potassium blood testing: The variability and repeatability of critical clinical tests. Mayo Clinic Proceedings. 2018;93(5):566-572. doi:10.1016/j.mayocp.2018.03.013
- Galloway CD, Valys AV, Shreibati JB, et al. Development and validation of a deep-learning model to screen for hyperkalemia from the electrocardiogram. JAMA Cardiology. 2019. 4(5):428-436. doi: 10.1001/jamacardio.2019.0640
- National Heart, Lung, and Blood Institute. Blood tests.
- Ialongo C, Bernardini S. Phlebotomy, a bridge between laboratory and patient. Biochem Med (Zagreb). 2016;26(1):17–33. doi:10.11613/BM.2016.002
- Schmidt ST, Ditting T, Deutsch B, et al. Circadian rhythm and day to day variability of serum potassium concentration: A pilot study. Journal of Nephrology. 2015. 28(2):165-72. doi:10.1007/s40620-014-0115-7
- Chatterjee R, Yeh HC, Shafi T, et al. Serum potassium and the racial disparity in diabetes risk: the Atherosclerosis Risk in Communities (ARIC) Study. American Journal of Clinical Nutrition. 2011. 93(5):1087-91. doi:10.3945/ajcn.110.007286
- Cleveland Clinic. Hyperkalemia (high blood potassium). Updated October 19, 2016.
- Cleveland Clinic. Low potassium levels in your blood (hypokalemia). Updated March 12, 2018.
- Kardalas E, Paschou SA, Anagostis P, et al. Hypokalemia: a clinical update. Endocrine Connections. 2018;7(4):R135-R146. doi:10.1530/EC-18-0109
- Cleveland Clinic. Low potassium levels in your blood (hypokalemia): Management and treatment. Updated March 12, 2018.
- Bnaya A, Ruchlemer R, Itzkowitz E, Gabbay E, Shavit L. Pseudohyperkalemia in chronic lymphocytic leukemia. American Journal of Medicine. 2020;133(2):e52-e53. doi:10.1016/j.amjmed.2019.07.037
- Ben Salem C, Badreddine A, Fathallah N, Slim R, Hmouda H. Drug-induced hyperkalemia. Drug Safety. 2014. 37(9):677-92. doi:10.1007/s40264-014-0196-1
- Cleveland Clinic. How can hyperkalemia (high blood potassium levels) be treated? Updated October 19, 2016.
- Miller KC. Plasma potassium concentration and content changes after banana ingestion in exercised men. J Athl Train. 2012;47(6):648–654. doi:10.4085/1062-6050-47.6.05
- American Association for Clinical Chemistry. Potassium. Updated 12/13/19.
- Jameson JL, et. al. Harrison's Principles of Internal Medicine, 20th Edition. McGraw Hill Education. 2018.
- Kovesdy CP, Appel LJ, Grams ME, et al. Potassium homeostasis in health and disease: A scientific workshop cosponsored by the National Kidney Foundation and the American Society of Hypertension. Journal of the American Society of Hypertension. 2017;11(12):783-800. doi:10.1016/j.jash.2017.09.011
- Nilsson E, Gasparini A, Arnlov J, et al. Incidence and determinants of hyperkalemia and hypokalemia in a large healthcare system. International Journal of Cardiology. 2017;15;245:277-284. doi:10.1016/j.ijcard.2017.07.035
- Pagana KD, Pagana TJ, Pagana TN. Mosby’s Diagnostic & Laboratory Test Reference. 14th ed. St. Louis, Mo: Elsevier; 2019.
- Schrier RW. Renal and Electrolyte Disorders, 8th Edition. LWW. 2017.
- Shrimanker I, Bhattarai S. Electrolytes. in: StatPearls. Updated January 20, 2020.
Writer Bio
Ruben J. Nazario has been a medical writer and editor since 2007. His work has appeared in national print and online publications. Nazario is a graduate of the University of Louisville School of Medicine, and is board-certified in pediatrics. He also has a Master of Arts in liberal studies from Skidmore College in Saratoga Springs, N.Y.