Cytokines & Diet
Inflammation is a silent contributor to some of the world's most common chronic diseases, including cancer, heart disease, diabetes and depression, according to a 2008 issue of "Scientific American." Cytokines -- the architects of your body's inflammation response -- are heavily influenced by the food in your diet. Consuming certain foods and avoiding others may help to control the activity of cytokines in your body.
Cytokines
In the Greek language, cytokines translates to "setting cells in motion." Cytokines are cells in your body that regulate immunity. They are especially important for regulating inflammation, a process that initially aids in healing after injury or infection. If inflammation becomes prolonged, however, it can result in tissue destruction and an increased risk of chronic disease, reports an article published in 2000 "News in Physiological Sciences." Certain foods in your diet largely dictate the activity and levels of pro-inflammatory and anti-inflammatory cytokines in your body.
Omega-3 Fats
Capillary Permeability and Inflammatory Response
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Omega-3 fatty acids are a healthy form of fat derived from marine life and certain plant foods, according to the University of Maryland Medical Center. Both omega-3 and omega-6 fats are precursors in the production of new cytokines. According to a 2008 article in "Lipids in Health and Disease," consuming inadequate omega-3 fats increases the production of cytokines from omega-6 fats, commonly found in vegetable oils. The cytokines derived from processes in your body that metabolize omega-6 fats are more likely to promote inflammation. Consume omega-3-rich fatty fish two times weekly, recommends the University of Maryland Medical Center.
Fruits and Vegetables
Fruits and vegetables are good sources of nutrients, including vitamin C, vitamin E and dietary fiber. A study published in the "American Journal of Clinical Nutrition" in 2005 discovered that consuming eight or more daily servings of colorful vegetables for four weeks reduced the concentration of cytokines significantly. The authors note that the vegetable's antioxidants may help to reduce cytokine activity.
Trans Fats
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Trans fat is a form of man-made fat found in hydrogenated oils and many baked goods. A research paper published in 2004 in the "American Journal of Clinical Nutrition," discovered that women who ate the most trans fat had the highest levels of pro-inflammatory cytokines in their blood when compared to women who avoided trans fat.
Related Articles
References
- "Scientific American"; Is Chronic Inflammation the Key to Unlocking the Mysteries of Cancer?; Gary Stix; November 2008
- "News in Physiological Sciences"; Inflammatory Cytokines in Nonpathological States; J Cannon; December 2000
- "Lipids in Health and Disease"; Modulation of Inflammatory Cytokines by Omega-3 Fatty Acids; J Kang et al.; May 2008
- University of Maryland Medical Center: Omega-3 Fatty Acids
- "American Journal of Clinical Nutrition"; A 4-wk intervention with high intake of carotenoid-rich vegetables and fruit reduces plasma C-reactive protein in healthy, nonsmoking men; B Waltz et al.; November 2005
- "American Journal of Clinical Nutrition"; Dietary intake of trans fatty acids and systemic inflammation in women; D Mozaffarian et al.; April 2004
Writer Bio
Ryan Devon is a registered dietitian with a Master of Science in nutrition and health promotion from Simmons College. He starting writing in 2010, specializing in weight management and eating-disorder science.