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At Healthfully, we strive to deliver objective content that is accurate and up-to-date. Our team periodically reviews articles in order to ensure content quality. The sources cited below consist of evidence from peer-reviewed journals, prominent medical organizations, academic associations, and government data.
- National Institutes of Health: Drug Info--Clobetasol Propionate
- Mayo Clinic: Lichen Sclerosus
- Mayo Clinic: Lichen Planus
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Clobetasol propionate is the generic name for Temovate, Clobex and Cormex cream 2. It is a corticosteroid used to treat a variety of skin conditions. Like other corticosteroids, clobetasol propionate is absorbed into the bloodstream with use and should be used only according to a physician's instructions. Clobetasol propionate is a prescription medication prescribed by many different types of doctors and specialists including gynecologists and dermatologists.
According to Mayo Clinic.com, lichen sclerosus is a rare, persistent skin condition that creates white, patchy and thin skin 34. It can appear anywhere on the body but most often occurs around the genital areas and is most common in post-menopausal women. Symptoms include:
- itching (sometimes severe)
- painful intercourse
- easy bruising or tearing of the skin
- wrinkled patches of skin
Although the causes of lichen sclerosus are not known, it is thought to be caused by a lack of sex hormones in the affected areas or an overactive immune system 3. Clobetasol propionate is used to treat lichen sclerosus and is often applied to areas of the skin several times a day for one or two weeks 3. Treatment with the cream can provide a more normal appearance of the skin and prevent further scarring.
Lichen Planus is an inflammatory skin condition that appears as pink or purple rows of itchy, flat bumps on the arms and legs 4. Lichen planus is an itchy rash that appears most often on the forearms, wrists and ankles 4. It can also appear on the back, on the scalp, under the nails and in the genital region. The cause of lichen planus is not known, although it appears to be triggered by hepatitis C or an allergic reaction to medication 4. Treatment for lichen planus varies according to the parts of the body affected 4. Clobetasol propionate is most often used to treat lichen planus found on the arms, legs and genital regions 4.
Eczema, or atopic dermatitis, is an itchy inflammation of the skin that is persistent and long-term. It is most often seen in children but can persist into adulthood. While eczema can affect many different areas of the body, it most often occurs at the elbows and behind the knees. The cause of eczema is not known, but it is most often attributed to a compromised or abnormal immune system. Symptoms include:
- raw skin
- bleeding skin
- red patches
- oozing or weeping patches of skin
- crusty areas of skin
Clobetasol propionate is often used periodically to reduce itching and scaling.
Psoriasis is a condition that affects the life cycle of skin cells. The condition causes cells to build up rapidly on the skin, causing itchy and dry red patches or thick, silvery scales. Psoriasis can cause pain in the joints, thickened nails and itching, burning or soreness. It is a persistent, long-term condition that comes in many types depending on where it is found in the body and which symptoms it causes. Psoriasis is related to T-cell immune responses that cause the body to attack healthy skin cells. Clobetasol propionate is used to treat mild to moderate psoriasis 1. It can help suppress the immune system, which gives the body time to heal. The cream is typically used on sensitive areas during outbreaks to help protect delicate areas of the body such as skin folds or the face.
Necrobiosis Lipoidica Diabeticorum
Necrobiosis lipoidica diabeticorum is a skin condition that occurs most often in women or diabetics. However, the cause of the condition is not known. Necrobiosis lipoidica diabeticorum causes large, red patches on the lower legs that can cause sores to develop and weep. Clobetasol propionate is sometimes used on the red patches in conjunction with coverings or airtight dressings.
Clobetasol propionate is used to treat lichen sclerosus and is often applied to areas of the skin several times a day for one or two weeks 3. Although the causes of lichen sclerosus are not known, it is thought to be caused by a lack of sex hormones in the affected areas or an overactive immune system 3. Necrobiosis lipoidica diabeticorum causes large, red patches on the lower legs that can cause sores to develop and weep.
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