Can Taking Too Many Vitamins Cause Liver and Kidney Damage?
There is an optimal daily intake (ODI) for every vitamin and mineral. For each person, this will vary based on age, gender, chronic medical conditions and the ability to absorb nutrients. It is not likely you will get too many vitamins from food consumption alone, but it is possible to take in too many vitamins with supplementation. Certain vitamins are worse than others, causing more issues if taken in excess.
Liver and Kidneys
The kidneys are responsible for producing hormones and vitamins. The liver detoxifies the body and must extract the needed and unwanted substances in all fluids and foods. It produces bile and stores and assimilates fat-soluble vitamins.
Vitamin A
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Active vitamin A in any form is stored in the liver; so intakes beyond recommended dosages could be toxic. Since the liver is the place of storage, too much might overwhelm this organ, causing it to overwork. The Hepatitis Foundation International warns of excess vitamin A intake as toxic to the liver 1. Taking in over 100,000 international units of vitamin A every day continuously for months could lead to toxicity symptoms such as nausea or vertigo.
- Active vitamin A in any form is stored in the liver; so intakes beyond recommended dosages could be toxic.
- The Hepatitis Foundation International warns of excess vitamin A intake as toxic to the liver 1.
Vitamin D
There are two types of vitamin D; D-2 and D-3. Both become the form of D your body needs after the liver and kidneys process them. Too much vitamin D intake leads to an excess of calcium in the blood. If excess continues, calcium deposits could end up in the kidneys and other organs.
- There are two types of vitamin D; D-2 and D-3.
- If excess continues, calcium deposits could end up in the kidneys and other organs.
Vitamin B-3
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For individuals without liver issues, taking miacin, or B-3, is not an issue. But for those with liver problems or disease, too much B-3 can elevate tests of liver function. Have a physician monitor your vitamin doses to be safe.
Vitamin C
Also, vitamin B-12 can be depleted, causing other health concerns, such as anemia. Dr. Lieberman recommends between 500 mg to 5,000 mg of vitamin C daily.
Take Vitamins Correctly
According to Dr. Lieberman, popping a bunch of vitamins at once is not ideal. Supplements are best taken with meals in most cases, and should be spread throughout the day. If you are taking 2,000 mg of vitamin C daily, take 1,000 mg twice a day with food, for example. Taking supplements correctly will improve their absorption and tolerance.
- According to Dr. Lieberman, popping a bunch of vitamins at once is not ideal.
- Supplements are best taken with meals in most cases, and should be spread throughout the day.
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References
- Hepatitis Foundation International: Caring for Your Liver
- Lab Tests Online: Kidney and Urinary Tract Function, Disorders and Diseases
- Gummin DD, Mowry JB, Spyker DA, Brooks DE, Osterthaler MK. 2017 annual report of the American Association of Poison Control Centers’ National Poison Data System (NPDS): 35th annual report. Clinical Toxicology. 2018 Dec;56(12):1213-1415. doi:10.1080/15563650.2018.1533727
- Olson KR, Anderson IB, Benowitz NL et al. Poisoning and Drug Overdose, Seventh Edition. McGraw-Hill Education / Medical; 2017.
- National Institutes of Health Office of Dietary Supplements. Niacin fact sheeet for health professionals. Updated July 9, 2019.
- National Institutes of Health Office of Dietary Supplements. Vitamin B6 fact sheet for health professionals. Updated September 19, 2019.
- National Institutes of Health Office of Dietary Supplements. Vitamin C fact sheet for health professionals. Updated July 9, 2019.
- MedlinePlus. Hypervitaminosis D. Updated November 17, 2017.
- Klein EA, Thompson IM Jr, Tangen CM, et al. Vitamin E and the risk of prostate cancer: the Selenium and Vitamin E Cancer Prevention Trial (SELECT). JAMA. 2011;306(14):1549–1556. doi:10.1001/jama.2011.1437
- Harvard Health Publishing. Listing of vitamins. Updated November 14, 2018.
- National Institutes of Health Office of Dietary Supplements. Vitamin A fact sheet for health professionals. Updated October 11, 2019.
- Ross CA. Encyclopedia of Dietary Supplements. Informa Healthcare, 2nd edition, 2010.
Writer Bio
Based in Colorado Springs, Vanessa Newman writes for "Women's Edition" magazine and has been published in "Rocky Mountain Sports," "IDEA" magazine and "The Teaching Professor." She has been writing professionally for over 10 years and holds a master's degree in sports medicine. She has written online courses for companies such as Anheuser-Busch and Chevron, but prefers creative writing.