Can Birth Control Pills Create High Cholesterol?
Birth control pills come in multiple forms consisting of different mixtures of reproductive hormones 3. Although birth control pills are widely used and effective, like all medications there are risks and benefits associated with their use 23. Birth control pills can affect your risk of cardiovascular disease, and they can cause a slight change in your cholesterol levels 3.
Cholesterol and Cardiovascular Risk Factors
Cholesterol is a fatty substance produced by your liver that is used in making new cells and in the production of hormones and bile acids. HDL cholesterol helps protect your heart and blood vessels, while LDL cholesterol increases your risk of cardiovascular disease 1. Too much cholesterol in your diet can lead to increased blood levels of cholesterol and a higher risk of developing cardiovascular disease, heart attack and stroke 1. Other cardiac risk factors include:
- smoking
- high blood pressure
- obesity
- diabetes
- family history
- lack of regular exercise
Birth Control Pills and Cholesterol
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Different types of birth control pills contain varied doses and proportions of estrogen and progestin, depending on your individual needs and reasons for taking them 3. Progestins have the opposite effect, lowering HDL and raising LDL cholesterol levels. Any effect birth control pills have on your cholesterol levels will depend on the relative amounts and proportions of hormones present, as well as your own body’s response to these hormones 3. In most cases, any changes that do occur will be small enough that they won’t negatively affect your health.
Other Cardiovascular Risks
In addition to changes in your cholesterol levels, birth control pills can have other side effects that impact your risk for cardiovascular disease 3. According to the Lahey Clinic, if you are a woman over 35 who takes birth control pills and smokes heavily, you are at an increased risk of heart attack and stroke 3. This risk is even higher if you have other cardiovascular risk factors, such as high blood pressure. Birth control pills also increase your risk of developing high blood pressure, especially if you are overweight, have high blood pressure in your family or smoke tobacco 3. The combination of birth control pills and smoking also increases your risk of developing blood clots 3.
Benefits of Birth Control Pills
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Birth control pills are considered safe and effective for most women, and have additional benefits to their contraceptive effect, according to Planned Parenthood 23. Talk to your health care provider about whether birth control pills are right for you, how your medical and family history might affect your risks, and which combination of hormones might be best for your individual situation 3.
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References
- Women’s Heart Foundation: Fats and Cholesterol
- MayoClinic.com: Birth Control FAQ: Benefits, Risks and Choices
- Planned Parenthood: Birth Control Pills
- Westhoff CL, Heartwell S, Edwards S, Zieman M, Stuart G, Cwiak C, Davis A, Robilotto T, Cushman L, & Kalmuss D. "Oral Contraceptive Discontinuation: Do Side Effects Matter?" American Journal of Obstetrics and Gynecology. April 2007; 196(4):412.e1–412.e7.
- Office on Women's Health. Birth control methods. Updated April 24, 2017.
- The American College of Obstetricians and Gynecologists. ACOG Practice Bulletin No. 110: noncontraceptive uses of hormonal contraceptives. Obstet Gynecol. 2010;115(1):206-18. doi: 10.1097/AOG.0b013e3181cb50b5
- National Cancer Institute. Oral contraceptives and cancer risk. Updated February 22, 2018.
- Westhoff CL, Heartwell S, Edwards S, et al. Oral contraceptive discontinuation: do side effects matter?. Am J Obstet Gynecol. 2007;196(4):412.e1-6 doi:10.1016/j.ajog.2006.12.015
- Committee on Gynecolic Practice. ACOG Committee Opinion Number 540: Risk of venous thromboembolism among users of drospirenone-containing oral contraceptive pills. Obstet Gynecol. 2012;120(5):1239-42. doi:10.1097/aog.0b013e318277c93b
- Cherala G, Edelman A. How can we improve oral contraceptive success in obese women?. Expert Rev Clin Pharmacol. 2015;8(1):1–3. doi:10.1586/17512433.2015.974558
- Lee CR. Drug interactions and hormonal contraception. Trends in Urology, Gynaecology & Sexual Health. 2009;14(3):23-26. doi:10.1002/tre.107
- The American College of Obstetricians and Gynecologists. Practice bulletin No. 110: Noncontraceptive Uses of Hormonal Contraceptives."Obstetrics & Gynecology. Jan 2010; 115(1):206-218. .
- Westhoff CL, Heartwell S, Edwards S, Zieman M, Stuart G, Cwiak C, Davis A, Robilotto T, Cushman L, & Kalmuss D. "Oral Contraceptive Discontinuation: Do Side Effects Matter?" American Journal of Obstetrics and Gynecology. April 2007; 196(4):412.e1–412.e7.
Writer Bio
Fred Schubert is a retired physician with both writing and teaching experience during his professional career, reaching back to 1983. Since 2009 he has been writing periodic articles on general science for his local newspaper, "The Dalles Chronicle." Schubert holds a Bachelor of Arts degree in biology and a M.D. from the Oregon Health Sciences University.