Antifungal Creams for the Groin

Fact Checked

iMan exercising in the gym image by Elzbieta Sekowska from

Both jock itch and yeast infections are caused by types of fungi. Jock itch affects the groin and thigh area in men when fungi overproduce in those areas. Yeast infections most often affect women in the vaginal area, but can also affect the male groin area. Treatment of these infections consists of one of various antifungal medications, including creams.


Nystatin antifungal cream is used to treat jock itch, athlete's foot and ringworm. explains that it works by weakening fungal cell membranes, which then makes the cell separate and die. In addition to applying the cream once per day for several days, the groin area must be cleansed thoroughly and kept dry.


Terbinafine is an antifungal cream that can be used to treat jock itch, athlete's foot and ringworm, but not vaginal yeast infections. This cream works just like Nystatin to destroy the cells of the fungi and cause them to die off. It should only be applied topically.

Vaginal Antifungals

Butoconazole, clotrimazole, miconazole and ticonazole are four over-the-counter creams that can be used to treat a vaginal yeast infection. These creams can weaken latex condoms, making them unreliable for pregnancy prevention. These creams also come in ointment and suppository form.


Clotrimazole is an antifungal medication that is sometimes paired with a steroid, betamethasone, to treat jock itch, according to The steroid helps treat the symptoms of jock itch--redness, swelling, itching and inflammation--while the antifungal kills the infection.

Tolnaftate Topical

Tolnaftate Topical is an antifungal medication that prevents fungus from growing on the skin, according to This is effective for the treatment of jock itch and several other fungal infections of the skin. In addition to being available as a cream, this drug can be found in powders, gels and sprays. It should only be used topically.