What does fact checked mean?
At Healthfully, we strive to deliver objective content that is accurate and up-to-date. Our team periodically reviews articles in order to ensure content quality. The sources cited below consist of evidence from peer-reviewed journals, prominent medical organizations, academic associations, and government data.
The information contained on this site is for informational purposes only, and should not be used as a substitute for the advice of a professional health care provider. Please check with the appropriate physician regarding health questions and concerns. Although we strive to deliver accurate and up-to-date information, no guarantee to that effect is made.
The drug Accutane, or isotretinoin, treats severe cases of acne, especially cystic or nodular acne that create painful lesions on and under the skin 1. Other brands of isotretinoin are available by prescription such as Claravis, Amnesteem and Sotret. Despite the efficacy of the drug, many would rather suffer the acne than the serious side effects of Accutane such as birth defects and liver failure 1. Alternatives to Accutane are available provide substitutes to using this drug 1.
A substitute closer to the chemical construction of Accutane is the retinoic creams, or those containing a form of retinol A. Retinol A, a derivative of vitamin A, has the same active ingredient in Accutane 1.
Retin-A 0.025 Cream Used for Wrinkles
Some severe cases of acne cover more than the face; cystic acne can affect the chest, neck and back. In these instances, use of a cream or lotion may not be the more efficient alternative to Accutane 1. Dermatologists have used antibiotics, such as doxycycline or tetracycline, for years as a front-line severe acne treatment. The oral antibiotics fight acne by decreasing the bacteria count on the surface of the skin.
- Some severe cases of acne cover more than the face; cystic acne can affect the chest, neck and back.
- The oral antibiotics fight acne by decreasing the bacteria count on the surface of the skin.
If oral or topical preparations are not an attractive option, there are cosmetic procedures to treat acne. MedlinePlus recognizes photodynamic therapy as one severe acne treatment option 2. This procedure uses lasers or pulsed light to treat the skin on the surface, similar to the effects of a little sun exposure. Dermatologists can complete glycolic acid peels and dermabrasion in their office which decrease the effects of acne.
- If oral or topical preparations are not an attractive option, there are cosmetic procedures to treat acne.
- This procedure uses lasers or pulsed light to treat the skin on the surface, similar to the effects of a little sun exposure.
Retin-A 0.025 Cream Used for Wrinkles
Retinol & Acne Scars
How to Stop Acne Scarring
Acne & Freckles
How to Treat Acne With Hydrocortisone
How to Get Rid of Allergic Reactions on Your Face Such As Blemishes Or Pimples
What Are the Benefits of Retinol Cream?
Home Remedy for an Infected Pimple
How to Heal Acne Right Above the Eyebrows
Alternatives to Retin-A
- Drugs.com: Accutane
- MedlinePlus: Acne
- Accutane Patient Information. Roche.
- Alikhan A, Henderson GP, Becker L, Sciallis GF. "Acne treatment and inflammatory bowel disease: what is the evidence?." J Am Acad Dermatol 2011 Sep;65:650-654. Epub 2011 Jun 24.
- Bernstein CN, Nugent Z, Longobardi T, Blanchard JF. "Isotretinoin is not associated with inflammatory bowel disease: a population-based case-control study." Am J Gastroenterol Nov 2009;104:2774-2778. Epub 2009 Jul 21.
- Crockett SD, Gulati A, Sandler RS, Kappelman MD. "A Causal Association Between Isotretinoin and Inflammatory Bowel Disease Has Yet to Be Established." Am J Gastroenterol Oct 2009;104: 2387-2393.
- Crockett SD, Porter CQ, Martin CF, Sandler RS, Kappelman MD. "Isotretinoin Use and the Risk of Inflammatory Bowel Disease: A Case-Control Study." Am J Gastroenterol Online.
- Etminan M, Bird ST, Delaney JA, Bressler B, Brophy JM. "Isotretinoin and risk for inflammatory bowel disease: a nested case-control study and meta-analysis of published and unpublished data." JAMADermatology. 2013;149:216-220.
- Margolis DJ, Fanelli M, Hoffstad O, Lewis JD. "Potential Association Between the Oral Tetracycline Class of Antimicrobials Used to Treat Acne and Inflammatory Bowel Disease." 10 Aug 2010 doi:10.1038.
- Reddy D, Siegel CA, Sands BE, Kane S. "Possible Association Between Isotretinoin and Inflammatory Bowel Disease." Am J Gastroenterol 2006;101: 1569–1573.
- Thakrar BT, Robinson NJ. "Isotretinoin use and the risk of inflammatory bowel disease." Am J Gastroenterol 2011 May;106:1000-1002; author reply 1002-3.
As a bachelor's-prepared registered nurse with more than 15 years of diversified experience, Juliet Wilkinson innerves our health-conscious population through expert articles. She is a motivated professional who believes that preventive care is the first step towards health and well-being.