In recent years, natural supplements have gained increasing attention for their reported benefits in improving mental and physical health. Chlorella, a single-celled algae, has been widely used throughout Asia and is often recommended by naturopathic doctors and other alternative health practitioners to treat a number of conditions. While some research suggests that chlorella may help to alleviate certain chronic fatigue conditions, other research indicates that chlorella may actually induce fatigue. Consult your doctor if you are thinking about taking a chlorella supplement.
If you are experiencing serious medical symptoms, seek emergency treatment immediately.
Chlorella is sold as a dietary supplement in powder, capsule, tablet and liquid form 1. The antioxidant benefits of chlorella have led proponents to claim it can help prevent cancer, enhance the immune system and fight infections 5. However, as of the date of publication, no scientific evidence supports these benefits. However, some research has shown that chlorella may help alleviate certain symptoms of chronic fatigue disorders like fibromyalgia. Interestingly, however, low doses of chlorella have also been reported to increase feelings of fatigue.
- Chlorella is sold as a dietary supplement in powder, capsule, tablet and liquid form 1.
- However, some research has shown that chlorella may help alleviate certain symptoms of chronic fatigue disorders like fibromyalgia.
Chlorella and Fatigue
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Studies on chlorella's benefits for reducing fatigue have been somewhat limited. Another study, published in 2006 in the "Annals of Nutrition and Metabolism," evaluated effects of a chlorella extract on laboratory mice exposed to a forced swim test and on fatigue-related parameters in their blood. The results found that the mice treated with chlorella had improved stamina, and that chlorella may also help to improve immune functioning. However, further studies are needed to fully determine the benefits of chlorella on fatigue in humans.
- Studies on chlorella's benefits for reducing fatigue have been somewhat limited.
- However, further studies are needed to fully determine the benefits of chlorella on fatigue in humans.
As of January 2014, only one study has shown fatigue as an adverse side effect of using chlorella supplementation. Study participants received a placebo, a 200 mg or a 400 milligram daily dose of chlorella for 28 days. Fatigue was reported more frequently as an adverse side effect by patients who received the 200 milligram dosage than by those who received either the placebo or the 400 milligram dosage.
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The American Cancer Society states that chlorella is reported to be safe in individuals who are not allergic; however, no studies have been conducted to determine the possibility of side effects or the potential effects of long-term use 5. As with any dietary supplement, inform your doctor if you plan to use chlorella. Never use dietary supplements as a replacement for conventional medical care.
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- "Healthy Healing: A Guide to Self-Healing for Everyone"; Linda Page; 2004
- Journal of Musculoskeletal Pain: Nutritional Supplementation with Chlorella pyrenoidosa for Fibromyalgia Syndrome: A Double-Blind, Placebo-Controlled, Crossover Study
- Annals of Nutrition and Metabolism: Oral Administration of Hot Water Extracts of Chlorella vulgaris Increases Physical Stamina in Mice
- Canadian Medical Association Journal: Safety and Immunoenhancing Effect of a Chlorella-Derived Dietary Supplement in Healthy Adults Undergoing Influenza Vaccination: Randomized, Double-Blind, Placebo-Controlled Trial
- American Cancer Society: Chlorella
- Kwak JH, Baek SH, Woo Y, et al. Beneficial immunostimulatory effect of short-term Chlorellasupplementation: enhancement of Natural Killer cell activity and early inflammatory response (Randomized, double-blinded, placebo-controlled trial). Nutr J. 2012;11:53. doi:10.1186/1475-2891-11-53.
- Azamai ESM, Sulaiman S, Habib SHM, et al. Chlorella vulgaris triggers apoptosis in hepatocarcinogenesis-induced rats. J Zhejiang Univ Sci B. 2009 Jan;10(1):14-21. doi:10.1631/jzus.B0820168.
- Azocar J, Diaz A. Efficacy and safety of Chlorella supplementation in adults with chronic hepatitis C virus infection. World J Gastroenterol. 2013 Feb 21;19(7):1085-90. doi:10.3748/wjg.v19.i7.1085.
- Nakano S, Takekoshi H, Nakano M. Chlorella pyrenoidosa supplementation reduces the risk of anemia, proteinuria and edema in pregnant women. Plant Foods Hum Nutr. 2010 Mar;65(1):25-30. doi:10.1007/s11130-009-0145-9.
- National Center for Complementary and Integrative Health. Traditional Chinese Medicine: What You Need To Know. Bethesda, Maryland; updated April 29, 2019.
- Ryu NH, Lim Y, Park JE, et al. Impact of daily Chlorella consumption on serum lipid and carotenoid profiles in mildly hypercholesterolemic adults: a double-blinded, randomized, placebo-controlled study. Nutr J. 2014 Jun 11;13:57. doi:10.1186/1475-2891-13-57.
Ashley Miller is a licensed social worker, psychotherapist, certified Reiki practitioner, yoga enthusiast and aromatherapist. She has also worked as an employee assistance program counselor and a substance-abuse professional. Miller holds a Master of Social Work and has extensive training in mental health diagnosis, as well as child and adolescent psychotherapy. She also has a bachelor's degree in music.